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CATH Superfamily 2.60.40.1170

Mu homology domain, subdomain B

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mu homology domain, subdomain B
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Mu homology domain, subdomain B

According to available literature the structural domains which comprise this superfamily share the structure of subdomain B of the mu homology domain which is found in endocytotic proteins involved in clathrin-mediated endocytosis (INTERPRO:IPR028565). The structure of this superfamilies' representative domain highlights the all beta-sheet structure of the mu homology domain with each subdomain, A and B respectively, showing a beta sandwich structure.

GO Diversity

Unique GO annotations
189 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
2458 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 56
Domain clusters (>95% seq id): 10
Domain clusters (>35% seq id): 8
Unique PDBs: 24
Alignments
Structural Clusters (5A): 3
Structural Clusters (9A): 2
FunFam Clusters: 108
Function
Unique EC:
Unique GO: 189
Taxonomy
Unique Species: 2458