The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 462: Interleukin 1 receptor accessory protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Interleukin-33 receptor activity GO:0002114
Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q61730 (/IMP) |
|
Interleukin-1 receptor activity GO:0004908
Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.
|
1 | Q61730 (/IDA) |
|
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
|
1 | Q63621 (/IPI) |
|
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
|
1 | Q61730 (/ISO) |
|
Interleukin-1 receptor binding GO:0005149
Interacting selectively and non-covalently with the interleukin-1 receptor.
|
1 | Q63621 (/TAS) |
|
Interleukin-1, type I receptor binding GO:0005150
Interacting selectively and non-covalently with a Type I interleukin-1 receptor.
|
1 | Q70YG5 (/IPI) |
|
Interleukin-1, type I receptor binding GO:0005150
Interacting selectively and non-covalently with a Type I interleukin-1 receptor.
|
1 | A0A060WD93 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q61730 (/IPI) |
|
Interleukin-1 binding GO:0019966
Interacting selectively and non-covalently with interleukin-1.
|
1 | Q63621 (/TAS) |
|
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | Q63621 (/TAS) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
10 | P59822 (/ISS) P59822 (/ISS) P59822 (/ISS) P59822 (/ISS) P59822 (/ISS) Q63621 (/ISS) Q9NPH3 (/ISS) Q9NPH3 (/ISS) Q9NPH3 (/ISS) Q9NPH3 (/ISS) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Interleukin-33-mediated signaling pathway GO:0038172
A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Interleukin-1-mediated signaling pathway GO:0070498
A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q61730 (/IDA) |
|
Positive regulation of interleukin-13 production GO:0032736
Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.
|
1 | Q61730 (/IMP) |
|
Positive regulation of interleukin-5 production GO:0032754
Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.
|
1 | Q61730 (/IMP) |
|
Interleukin-33-mediated signaling pathway GO:0038172
A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q61730 (/IMP) |
|
Interleukin-2 biosynthetic process GO:0042094
The chemical reactions and pathways resulting in the formation of interleukin-2.
|
1 | Q61730 (/IDA) |
|
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
1 | Q61730 (/IMP) |
|
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
|
1 | Q61730 (/IDA) |
|
Interleukin-4 secretion GO:0072602
The regulated release of interleukin-4 from a cell.
|
1 | Q61730 (/IMP) |
|
Regulation of postsynaptic density assembly GO:0099151
Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
|
1 | Q61730 (/IDA) |
|
Regulation of postsynaptic density assembly GO:0099151
Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
|
1 | Q61730 (/IMP) |
|
Trans-synaptic signaling by trans-synaptic complex GO:0099545
Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.
|
1 | Q61730 (/IDA) |
|
Trans-synaptic signaling by trans-synaptic complex GO:0099545
Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.
|
1 | Q61730 (/IMP) |
|
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q61730 (/IDA) |
|
Synaptic membrane adhesion GO:0099560
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
|
1 | Q61730 (/IMP) |
|
Regulation of presynapse assembly GO:1905606
Any process that modulates the frequency, rate or extent of presynapse assembly.
|
1 | Q61730 (/IDA) |
|
Regulation of presynapse assembly GO:1905606
Any process that modulates the frequency, rate or extent of presynapse assembly.
|
1 | Q61730 (/IMP) |
|
Positive regulation of interleukin-6 secretion GO:2000778
Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
|
1 | Q61730 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) Q9NPH3 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
4 | Q9NPH3 (/HDA) Q9NPH3 (/HDA) Q9NPH3 (/HDA) Q9NPH3 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q61730 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q63621 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q61730 (/ISO) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q63621 (/IDA) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q61730 (/ISO) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | Q61730 (/IDA) |
|
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
|
1 | Q61730 (/IMP) |