The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 348: Interleukin 20 receptor subunit alpha
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q13651 (/IPI) Q80XF5 (/IPI) Q8N6P7 (/IPI) Q9UHF4 (/IPI) |
|
Interleukin-10 receptor activity GO:0004920
Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
2 | Q61727 (/ISO) Q61727 (/ISO) |
|
Interleukin-10 binding GO:0019969
Interacting selectively and non-covalently with interleukin-10.
|
2 | Q61727 (/ISO) Q61727 (/ISO) |
|
Interleukin-20 binding GO:0042015
Interacting selectively and non-covalently with interleukin-20.
|
2 | Q6PHB0 (/IPI) Q80XZ4 (/IPI) |
|
Interferon receptor activity GO:0004904
Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q8N6P7 (/TAS) |
|
Interleukin-10 receptor activity GO:0004920
Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | G3V830 (/IMP) |
|
Interleukin-10 receptor activity GO:0004920
Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q13651 (/TAS) |
|
Interleukin-10 binding GO:0019969
Interacting selectively and non-covalently with interleukin-10.
|
1 | G3V830 (/IMP) |
|
Interleukin-10 binding GO:0019969
Interacting selectively and non-covalently with interleukin-10.
|
1 | G3V830 (/IPI) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
1 | Q13651 (/TAS) |
|
Interleukin-22 binding GO:0042017
Interacting selectively and non-covalently with interleukin-22.
|
1 | Q969J5 (/IDA) |
|
Interleukin-22 binding GO:0042017
Interacting selectively and non-covalently with interleukin-22.
|
1 | Q80XF5 (/ISO) |
|
Interleukin-22 receptor activity GO:0042018
Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q969J5 (/IDA) |
|
Interleukin-22 receptor activity GO:0042018
Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q80XF5 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
4 | Q13651 (/TAS) Q8N6P7 (/TAS) Q969J5 (/TAS) Q9UHF4 (/TAS) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
2 | Q61727 (/ISO) Q61727 (/ISO) |
|
Positive regulation of receptor signaling pathway via JAK-STAT GO:0046427
Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
|
2 | Q61727 (/ISO) Q61727 (/ISO) |
|
Regulation of synapse organization GO:0050807
Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
2 | Q61727 (/ISO) Q61727 (/ISO) |
|
Ubiquitin-dependent endocytosis GO:0070086
Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
|
2 | Q61727 (/ISO) Q61727 (/ISO) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q13651 (/IDA) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q6PHB0 (/IMP) |
|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | G3V830 (/IEP) |
|
Regulation of tyrosine phosphorylation of STAT protein GO:0042509
Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
|
1 | Q80XF5 (/IDA) |
|
Regulation of tyrosine phosphorylation of STAT protein GO:0042509
Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
|
1 | Q969J5 (/ISS) |
|
Regulation of bone resorption GO:0045124
Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).
|
1 | Q6PHB0 (/IMP) |
|
Positive regulation of receptor signaling pathway via JAK-STAT GO:0046427
Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
|
1 | Q13651 (/IDA) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
1 | Q80XF5 (/IMP) |
|
Regulation of synapse organization GO:0050807
Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
1 | G3V830 (/IMP) |
|
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | Q80XZ4 (/IMP) |
|
Ubiquitin-dependent endocytosis GO:0070086
Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
|
1 | Q13651 (/IDA) |
|
Positive regulation of intrinsic apoptotic signaling pathway GO:2001244
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
1 | Q6PHB0 (/IGI) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q13651 (/TAS) Q8N6P7 (/TAS) Q9UHF4 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q61727 (/ISO) Q61727 (/ISO) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q969J5 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q969J5 (/NAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q80XF5 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q13651 (/IDA) |
