The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36: Sphingosine kinase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sphinganine kinase activity GO:0008481
Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate.
3 F2Y4A3 (/IDA) Q8L7L1 (/IDA) Q8L7L1 (/IDA)
D-erythro-sphingosine kinase activity GO:0017050
Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP.
3 F2Y4A3 (/IDA) Q8L7L1 (/IDA) Q8L7L1 (/IDA)
D-erythro-sphingosine kinase activity GO:0017050
Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP.
2 Q8L7L1 (/TAS) Q8L7L1 (/TAS)
Phosphatidic acid binding GO:0070300
Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
1 F2Y4A3 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sphingolipid metabolic process GO:0006665
The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
3 F2Y4A3 (/IDA) Q8L7L1 (/IDA) Q8L7L1 (/IDA)
Sphingolipid metabolic process GO:0006665
The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
3 F2Y4A3 (/IMP) Q8L7L1 (/IMP) Q8L7L1 (/IMP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
3 F2Y4A3 (/IMP) Q8L7L1 (/IMP) Q8L7L1 (/IMP)
Cellular response to abscisic acid stimulus GO:0071215
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
3 F2Y4A3 (/IMP) Q8L7L1 (/IMP) Q8L7L1 (/IMP)
Seed germination GO:0009845
The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.
2 Q8L7L1 (/IMP) Q8L7L1 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plant-type vacuole membrane GO:0009705
The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
3 F2Y4A3 (/IDA) Q8L7L1 (/IDA) Q8L7L1 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
2 Q8L7L1 (/IDA) Q8L7L1 (/IDA)