The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: Ceramide kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ceramide kinase activity GO:0001729
Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.
5 C0LT23 (/IDA) Q6USK2 (/IDA) Q8K4Q7 (/IDA) Q8TCT0 (/IDA) Q8TCT0 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 Q8TCT0 (/IDA) Q8TCT0 (/IDA)
Ceramide kinase activity GO:0001729
Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.
2 Q8TCT0 (/TAS) Q8TCT0 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q8TCT0 (/IPI) Q8TCT0 (/IPI)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q8K4Q7 (/ISO)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q8K4Q7 (/ISS)
Ceramide kinase activity GO:0001729
Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.
1 Q8K4Q7 (/IMP)
Ceramide kinase activity GO:0001729
Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.
1 Q8K4Q7 (/ISO)
Ceramide kinase activity GO:0001729
Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.
1 Q8K4Q7 (/ISS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q6USK2 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ceramide metabolic process GO:0006672
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
4 C0LT23 (/IDA) Q6USK2 (/IDA) Q8TCT0 (/IDA) Q8TCT0 (/IDA)
Ceramide metabolic process GO:0006672
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
2 Q8TCT0 (/TAS) Q8TCT0 (/TAS)
Glycosphingolipid metabolic process GO:0006687
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
2 Q8TCT0 (/TAS) Q8TCT0 (/TAS)
Ceramide metabolic process GO:0006672
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
1 Q8K4Q7 (/ISO)
Ceramide metabolic process GO:0006672
The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
1 Q8K4Q7 (/ISS)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
1 Q6USK2 (/IMP)
Regulation of programmed cell death GO:0043067
Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
1 Q6USK2 (/IMP)
Negative regulation of programmed cell death GO:0043069
Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
1 C0LT23 (/IDA)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8TCT0 (/IDA) Q8TCT0 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8TCT0 (/TAS) Q8TCT0 (/TAS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8TCT0 (/IDA) Q8TCT0 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8K4Q7 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8K4Q7 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8K4Q7 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8K4Q7 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8K4Q7 (/ISS)