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CATH Superfamily 2.60.200.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Nuclear inhibitor of protein phosphatase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 34 B1WC70 (/IPI) Q12972 (/IPI) Q12972 (/IPI) Q12972 (/IPI) Q12972 (/IPI) Q12972 (/IPI) Q12972 (/IPI) Q12972 (/IPI) Q12972 (/IPI) Q12972 (/IPI)
(24 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
 32 Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS)
(22 more)
Protein serine/threonine phosphatase inhibitor activity GO:0004865
Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
 32 Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS)
(22 more)
Ribonuclease E activity GO:0008995
Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
 32 Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS)
(22 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
 1 Q9V7W9 (/IDA)
Protein phosphatase inhibitor activity GO:0004864
Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
 1 Q9V7W9 (/IMP)
Protein serine/threonine phosphatase inhibitor activity GO:0004865
Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
 1 Q9V7W9 (/IDA)
Protein phosphatase 1 binding GO:0008157
Interacting selectively and non-covalently with the enzyme protein phosphatase 1.
 1 Q9V7W9 (/IPI)
Protein phosphatase regulator activity GO:0019888
Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
 1 Q8R3G1 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA catabolic process GO:0006401
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
 32 Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS)
(22 more)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
 1 Q9V7W9 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
 1 Q8R3G1 (/IMP)
Negative regulation of protein dephosphorylation GO:0035308
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.
 1 Q9V7W9 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
 33 Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA)
(23 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
 32 Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS) Q12972 (/TAS)
(22 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
 32 Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA) Q12972 (/IDA)
(22 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
 1 Q8R3G1 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
 1 Q8R3G1 (/ISO)