The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: neuronal pentraxin receptor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
5 F8VQB8 (/IPI) H3BLN6 (/IPI) Q6TKP2 (/IPI) Q6TLW0 (/IPI) Q6TLW1 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 A2AVA0 (/IDA)
Pentraxin receptor activity GO:0008029
Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1 O35764 (/IDA)
Pentraxin receptor activity GO:0008029
Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1 Q99J85 (/ISO)
Pentraxin receptor activity GO:0008029
Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1 F1SNX9 (/ISS)
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
1 Q99J85 (/IPI)
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
1 F1SNX9 (/ISS)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 O35764 (/IDA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 Q99J85 (/ISO)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 F1SNX9 (/ISS)

There are 35 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of synaptic transmission, glutamatergic GO:0051966
Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
4 A0A2R9YJK1 (/IMP) A8E4K4 (/IMP) D2D0C1 (/IMP) Q6DG61 (/IMP)
Regulation of postsynaptic neurotransmitter receptor activity GO:0098962
Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
4 O95502 (/IMP) P47972 (/IMP) P47972 (/IMP) Q15818 (/IMP)
Regulation of postsynaptic neurotransmitter receptor activity GO:0098962
Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
4 O70340 (/ISO) Q62443 (/ISO) Q62443 (/ISO) Q99J85 (/ISO)
Neurotransmitter receptor localization to postsynaptic specialization membrane GO:0099645
A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
4 O70340 (/ISO) Q62443 (/ISO) Q62443 (/ISO) Q99J85 (/ISO)
Regulation of postsynaptic neurotransmitter receptor activity GO:0098962
Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
3 P47972 (/IDA) P47972 (/IDA) Q15818 (/IDA)
Neurotransmitter receptor localization to postsynaptic specialization membrane GO:0099645
A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
3 O35764 (/IDA) P47971 (/IDA) P97738 (/IDA)
Neurotransmitter receptor localization to postsynaptic specialization membrane GO:0099645
A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
3 O35764 (/IMP) P47971 (/IMP) P97738 (/IMP)
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
2 Q62443 (/ISO) Q62443 (/ISO)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 P47972 (/NAS) P47972 (/NAS)
Cellular response to potassium ion GO:0035865
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
2 Q62443 (/ISO) Q62443 (/ISO)
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
2 D2D0C0 (/IMP) F1Q689 (/IMP)
Mitochondrial fragmentation involved in apoptotic process GO:0043653
The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
2 Q62443 (/ISO) Q62443 (/ISO)
Regulation of neuronal synaptic plasticity GO:0048168
A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
2 D2D0C0 (/IMP) F1Q689 (/IMP)
Axonogenesis involved in innervation GO:0060385
The neurite development process that generates a long process of a neuron, as it invades a target tissue.
2 Q62443 (/IGI) Q62443 (/IGI)
Regulation of postsynaptic density assembly GO:0099151
Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
2 Q62443 (/ISO) Q62443 (/ISO)
Lymph vessel development GO:0001945
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
1 A0A1D5NSM8 (/IMP)
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
1 P47971 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 F1SNX9 (/ISS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q15818 (/TAS)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 Q15818 (/TAS)
Associative learning GO:0008306
Learning by associating a stimulus (the cause) with a particular outcome (the effect).
1 O70340 (/IMP)
Epidermal cell differentiation GO:0009913
The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.
1 A0A1D5NSM8 (/IMP)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q99J85 (/IMP)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 F1SNX9 (/ISS)
Cellular response to potassium ion GO:0035865
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
1 P47971 (/IDA)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 O35764 (/IEP)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 F1SNX9 (/ISS)
Mitochondrial fragmentation involved in apoptotic process GO:0043653
The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
1 P47971 (/IMP)
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 P47971 (/IEP)
Regulation of postsynaptic specialization assembly GO:0099150
Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.
1 Q99J85 (/IDA)
Regulation of postsynaptic specialization assembly GO:0099150
Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.
1 Q99J85 (/IMP)
Regulation of postsynaptic density assembly GO:0099151
Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
1 P47971 (/EXP)
Regulation of postsynaptic density assembly GO:0099151
Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
1 P47971 (/IDA)
Regulation of postsynaptic density assembly GO:0099151
Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
1 P47971 (/IMP)
Neurotransmitter receptor localization to postsynaptic specialization membrane GO:0099645
A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
1 P47971 (/EXP)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
7 O95502 (/IMP) P47971 (/IMP) P47972 (/IMP) P47972 (/IMP) P97738 (/IMP) Q15818 (/IMP) Q99J85 (/IMP)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 F8VQB8 (/IDA) H3BLN6 (/IDA) P47971 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
6 P47971 (/IDA) P47972 (/IDA) P47972 (/IDA) P97738 (/IDA) Q15818 (/IDA) Q99J85 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 F8VQB8 (/IDA) H3BLN6 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 F8VQB8 (/IDA) H3BLN6 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
5 F8VQB8 (/IDA) H3BLN6 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
5 F8VQB8 (/IDA) H3BLN6 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
5 F8VQB8 (/IDA) H3BLN6 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
5 F8VQB8 (/IDA) H3BLN6 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
5 F8VQB8 (/IDA) H3BLN6 (/IDA) Q6TKP2 (/IDA) Q6TLW0 (/IDA) Q6TLW1 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
4 O70340 (/ISO) Q62443 (/ISO) Q62443 (/ISO) Q99J85 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 O35764 (/IDA) P47971 (/IDA) Q99J85 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q62443 (/ISO) Q62443 (/ISO) Q99J85 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q62443 (/ISO) Q62443 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q62443 (/ISO) Q62443 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
2 Q62443 (/ISO) Q62443 (/ISO)
Synaptic cleft GO:0043083
The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.
2 Q62443 (/ISO) Q62443 (/ISO)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 A2AVA0 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 A2AVA0 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 O35764 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q99J85 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 F1SNX9 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P47971 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 F1SNX9 (/ISS)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 P47971 (/IDA)
Synaptic cleft GO:0043083
The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.
1 P47971 (/IDA)
Extrinsic component of postsynaptic specialization membrane GO:0098892
The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 P97738 (/IDA)
Extrinsic component of postsynaptic specialization membrane GO:0098892
The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 P97738 (/IMP)
Extrinsic component of postsynaptic specialization membrane GO:0098892
The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 O70340 (/ISO)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 P47971 (/EXP)
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