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Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Jelly Rolls
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1193
3D
4r8hB01 - 79.5
3
985
3D
3mzhB01 - 97.9
2
968 - - 91.7
4
869
3D
5e44A01 - 92.6
6
649
3D
5kjzA00 - 91.9
5
648
3D
2eteB00 - 96.0
7
638
3D
3u0zB02 - 72.7
9
574
3D
4lloG00 - 74.0
8
GEF
569 - - 25.6
10
565 - - 92.5
11
526 - - 80.6
12
506 - - 96.1
13
465
3D
4dinB01 - 76.6
14
Eag-related
418
3D
3ukvC02 - 76.0
15
401
3D
4mh0E02 - 49.0
16
380
3D
2oyzA00 - 91.0
17
370
3D
4x6qB01 - 87.3
18
353
3D
1xruB02 - 80.6
19
321
3D
2d93A00 - 44.7
20
304 - - 89.4
21
297
3D
1tq5A02 - 57.6
22
293 - - 84.2
23
287
3D
5nw7A02 - 85.6
24
262
3D
1wgpA01 - 79.8
25
254 - - 97.3
26
244 - - 65.1
27
236
3D
4jvaA02 - 73.2
28
221 - - 24.6
30
215
3D
5zvxA02 - 96.8
29
214 - - 20.1
31
191
3D
4qgnA00 - 83.9
35
184
3D
4z07E00 - 81.5
45
181
3D
2q4sA00 - 82.5
37
179
3D
5jd7A00 - 68.1
32
178 - - 93.3
33
176
3D
2vpvB00 - 98.9
34
171 - - 90.9
36
167 - - 59.3
42
157
3D
5opcA01 - 90.1
38
141
3D
6bq8A00 - 88.3
39
127
3D
3of1A01 - 94.0
43
124
3D
5c8wF00 - 81.5
40
121 - - 63.9
73
121
3D
1ud1C02 - 97.3
41
120 - - 9.9
44
116 - - 95.9
51
112
3D
1dztB00 - 73.3
46
112 - - 73.0
47
108 - - 94.0
48
106 - - 72.7
49
104 - - 14.7
50
103 - - 3.4
54
100
3D
3la7B01 - 47.2
52
99
3D
4f7zA01 - 31.3
53
96 - - 68.7
56
93
3D
4qgmA00 - 83.2
57
92
3D
4d7tB02 - 98.2
55
92 - - 83.2
58
86 - - 28.1
59
85 - - 87.3
61
84 - - 64.5
60
84 - - 72.2
62
84 - - 83.6
63
80 - - 61.8
64
77 - - 88.4
65
71 - - 11.4
68
69
3D
5e16A00 - 95.6
66
69 - - 9.7
67
68 - - 93.4
69
67 - - 47.6
70
66 - - 74.7
71
65 - - 6.4
72
65 - - 84.7
81
63
3D
6h1iA01 - 72.2
77
61
3D
5tkqA00 - 90.4
80
60
3D
1lrhD00 - 74.3
74
60 - - 99.0
75
59 - - 31.3
76
58 - - 25.9
78
54 - - 78.8
79
53 - - 83.0
137
S
52
3D
4e2sP00 - 41.5
82
50 - - 12.1
83
49 - - 95.3
84
S
49
3D
1rc6B00 - 8.8
124
48
3D
1ud1C01 - 92.0
162
47
3D
1caxF00 - 80.1
86
47 - - 84.7
85
47 - - 11.5
88
46 - - 53.1
87
46 - - 0.0
89
45 - - 95.2
91
45
3D
4ofgA00 - 24.4
90
44 - - 73.1
93
44
3D
1zvfB01 - 80.3
92
43 - - 24.2
94
42 - - 17.9
95
41 - - 2.6
96
40 - - 38.8
100
40
3D
3iwzD01 - 7.9
181
39
3D
1uikC01 - 73.9
212
38
3D
5x6eN01 - 0.0
97
38 - - 46.7
98
38 - - 86.7
99
37 - - 92.8
382
S
36
3D
4j1xC02 - 48.8
101
36 - - 7.3
105
32 - - 50.7
104
32 - - 77.5
103
32 - - 6.7
102
32 - - 70.3
106
30 - - 15.1
107
27 - - 88.5
113
27
3D
2qvsB02 - 39.4
108
27 - - 80.3
111
26 - - 88.7
118
26
3D
3of1A02 - 88.1
110
26 - - 9.7
112
26 - - 18.0
109
26 - - 85.3
117
25 - - 45.6
116
25 - - 9.5
129
25
3D
4i2oB01 - 76.1
115
25 - - 13.7
114
25 - - 12.4
119
24 - - 22.5
123
24 - - 97.3
122
24 - - 90.6
121
24 - - 2.6
120
24 - - 82.3
139
24
3D
3h7yB02 - 9.3
126
23 - - 3.6
125
23 - - 23.9
127
23 - - 25.5
130
23 - - 80.0
128
23 - - 3.5
165
22
3D
2ixcD00 - 56.4
133
22 - - 41.0
132
22 - - 9.0
131
22 - - 75.0
135
21 - - 71.8
134
21 - - 5.3
136
20 - - 63.2
141
20 - - 86.2
140
20 - - 8.4
142
putative
20 - - 79.7
138
20 - - 16.0
143
19 - - 2.0
156
19
3D
5kbfB01 - 2.8
146
19 - - 73.7
145
19 - - 73.4
144
19 - - 45.3
157
19
3D
2zcwA01 - 77.8
148
18 - - 85.7
147
2OG II
18 - - 65.6
154
17 - - 81.4
155
17 - - 7.2
153
Crp/Fnr family
17 - - 14.2
149
17 - - 72.1
152
17 - - 17.2
151
17 - - 15.5
158
17 - - 5.6
150
17 - - 88.8
164
16 - - 23.5
163
16 - - 9.4
159
16 - - 34.1
160
16 - - 0.0
161
16 - - 0.0
166
15 - - 60.4
170
15 - - 19.8
171
15 - - 17.4
172
15 - - 36.0
173
15 - - 71.7
274
15
3D
3bu7B00 - 90.5
228
15
3D
4avcB01 - 34.9
167
15 - - 3.9
168
15 - - 27.7
169
Catabolite gene activator
15 - - 16.0
178
14 - - 12.5
177
14 - - 11.8
175
14 - - 19.4
174
14 - - 63.8
176
14 - - 11.9
180
13 - - 9.6
179
13 - - 2.3
182
13 - - 1.4
183
13 - - 10.6
186
13 - - 27.9
184
13 - - 36.0
185
13 - - 10.3
192
12 - - 88.1
188
12 - - 44.2
197
12 - - 71.5
189
12 - - 71.1
187
12 - - 56.8
190
12 - - 0.0
191
12 - - 14.5
196
12 - - 10.1
516
12
3D
4tlfD02 - 0.8
195
12 - - 0.0
194
12 - - 16.6
193
12 - - 54.6
203
11 - - 9.8
198
11 - - 42.7
204
11 - - 0.0
199
11 - - 11.8
201
11 - - 0.0
200
11 - - 11.0
202
11 - - 6.3
217
10 - - 0.0
211
10 - - 32.1
210
10 - - 17.5
205
10 - - 76.8
218
10 - - 2.8
219
10 - - 0.0
206
10 - - 65.4
209
10 - - 0.0
268
10
3D
2z69C00 - 4.2
220
10 - - 92.4
216
10 - - 79.8
215
10 - - 47.3
214
10 - - 39.1
208
10 - - 13.2
284
10
3D
1vp6C00 - 21.7
304
10
3D
2xlgA00 - 39.8
207
10 - - 83.6
213
MCD
10 - - 14.8
233
9 - - 0.0
223
9 - - 7.7
226
9 - - 10.6
235
9 - - 18.2
234
9 - - 0.0
224
9 - - 46.4
225
9 - - 77.1
221
9 - - 8.6
231
9 - - 12.4
230
9 - - 41.8
391
9
3D
1j3rB00 - 8.3
229
9 - - 7.6
227
9 - - 2.2
222
9 - - 81.5
232
9 - - 1.6
246
8 - - 88.8
253
8 - - 90.2
263
8
3D
1zybA01 - 10.2
245
8 - - 38.9
244
8 - - 72.4
236
8 - - 17.5
243
8 - - 51.4
242
8 - - 35.4
247
8 - - 17.9
238
8 - - 15.6
239
8 - - 9.2
251
8 - - 66.1
250
8 - - 25.6
237
8 - - 67.3
241
8 - - 9.7
240
8 - - 5.5
248
8 - - 3.4
252
8 - - 67.5
249
8 - - 93.8
272
7 - - 0.0
266
7 - - 0.0
409
7
3D
4yarA03 - 12.1
254
7 - - 8.4
255
7 - - 27.1
264
7 - - 0.0
265
7 - - 0.0
270
7 - - 0.0
256
7 - - 5.5
271
7 - - 1.3
260
7 - - 0.0
259
7 - - 15.7
261
7 - - 22.5
269
7 - - 2.0
258
7 - - 10.6
273
7 - - 79.7
262
7 - - 12.2
267
7 - - 71.0
257
7 - - 0.9
282
6 - - 0.0
298
6 - - 21.7
290
6 - - 43.0
287
6 - - 7.0
291
6 - - 5.8
301
6 - - 37.3
299
6 - - 77.6
300
6 - - 40.9
277
6 - - 10.1
281
6 - - 0.9
297
6 - - 0.0
288
6 - - 12.7
292
6 - - 22.1
279
6 - - 12.2
280
6 - - 5.7
289
6 - - 84.0
278
6 - - 7.6
275
6 - - 18.4
286
6 - - 18.4
276
6 - - 21.7
293
6 - - 0.9
285
6 - - 8.6
296
6 - - 0.0
295
6 - - 0.0
294
6 - - 0.0
283
6 - - 86.7
309
5 - - 0.0
321
5 - - 67.6
331
5 - - 0.0
330
5 - - 6.6
328
5 - - 0.0
320
5 - - 42.9
316
5 - - 0.0
329
5 - - 1.3
308
5 - - 0.0
314
5 - - 14.7
315
5 - - 12.5
327
5 - - 1.9
337
5 - - 53.8
322
5 - - 14.3
332
5 - - 61.8
307
5 - - 14.7
302
5 - - 70.7
313
5 - - 22.2
317
5 - - 9.4
312
5 - - 70.1
303
5 - - 14.6
333
5 - - 77.6
323
5 - - 8.2
311
5 - - 47.3
310
5 - - 0.0
397
5
3D
1o4tB00 - 0.0
318
5 - - 35.9
305
5 - - 62.3
336
5 - - 18.4
326
5 - - 11.2
319
5 - - 46.1
334
5 - - 50.5
335
5 - - 73.8
325
5 - - 3.9
324
5 - - 0.0
306
5 - - 45.5
342
4 - - 34.3
587
4
3D
3b02A01 - 1.1
360
4 - - 72.4
374
4 - - 0.0
347
4 - - 12.5
359
4 - - 60.0
368
4 - - 5.5
375
4 - - 35.1
338
4 - - 47.4
361
4 - - 6.7
339
4 - - 6.3
376
4 - - 64.3
351
4 - - 9.3
350
4 - - 12.2
358
4 - - 16.9
369
4 - - 11.8
373
4 - - 6.8
341
4 - - 16.8
362
4 - - 0.8
340
4 - - 0.0
348
4 - - 0.0
367
4 - - 11.6
352
4 - - 3.0
357
4 - - 10.2
349
4 - - 14.4
346
4 - - 2.4
353
4 - - 7.0
363
4 - - 7.0
372
4 - - 1.9
344
4 - - 48.8
377
4 - - 72.4
345
4 - - 66.0
585
4
3D
1ft9B01 - 0.0
366
4 - - 0.0
381
4 - - 75.0
379
4 - - 78.5
355
4 - - 30.6
354
4 - - 49.5
380
4 - - 85.9
378
4 - - 80.6
365
4 - - 2.9
364
4 - - 8.1
370
4 - - 8.3
356
4 - - 8.4
343
4 - - 36.3
371
4 - - 9.4
427
3 - - 13.8
437
3 - - 60.0
422
3 - - 0.0
441
3 - - 45.4
432
3 - - 4.7
386
3 - - 5.4
440
3 - - 71.1
407
3 - - 15.8
393
3 - - 0.0
402
3 - - 0.0
413
3 - - 40.6
385
3 - - 12.1
384
3 - - 10.8
421
3S
3 - - 13.4
431
3 - - 14.0
442
3 - - 60.4
396
3 - - 7.6
428
3 - - 8.4
430
3 - - 1.8
420
3 - - 2.5
438
3 - - 20.7
416
3 - - 72.7
429
3 - - 7.1
401
3 - - 0.0
394
3 - - 0.0
395
3 - - 0.0
439
3 - - 41.1
415
3 - - 71.5
414
3 - - 38.8
408
3 - - 4.5
400
3 - - 2.9
383
3 - - 43.0
398
3 - - 0.0
411
3 - - 0.0
390
3 - - 7.3
387
3 - - 24.1
410
3 - - 3.9
405
3 - - 8.9
404
3 - - 21.0
418
3 - - 0.8
436
3 - - 0.0
426
3 - - 11.9
419
3 - - 5.6
435
3 - - 0.0
399
3 - - 0.0
434
3 - - 0.0
424
3 - - 11.1
425
3 - - 8.3
443
3 - - 69.3
406
3 - - 6.0
417
3S
3 - - 9.0
412
3 - - 64.1
403
3 - - 32.4
392
3 - - 4.4
388
3 - - 48.2
389
3 - - 78.5
433
3 - - 6.8
423
3 - - 0.6
444
3 - - 16.3
582
2 - - 0.0
598
2 - - 42.3
517
2 - - 10.3
590
2 - - 36.1
496
2 - - 8.6
473
2 - - 26.1
512
2 - - 6.0
546
2 - - 40.2
591
2 - - 39.6
503
2 - - 23.3
462
2 - - 20.2
553
2 - - 25.6
467
2 - - 16.8
448
2 - - 0.0
495
2 - - 4.1
494
2 - - 6.6
452
2 - - 0.0
563
2 - - 7.2
449
2 - - 0.0
457
2 - - 0.0
599
2 - - 42.9
533
2 - - 2.0
572
2 - - 0.0
523
2 - - 0.9
544
2 - - 26.9
545
2 - - 31.9
577
2 - - 0.0
483
2 - - 5.1
566
2 - - 1.1
511
2 - - 12.7
581
2 - - 0.0
460
2 - - 43.2
475
2 - - 0.0
459
2 - - 22.6
468
2 - - 34.6
447
2 - - 0.0
474
2 - - 0.0
603
2 - - 43.4
510
2 - - 41.2
597
2 - - 41.4
518
2 - - 0.0
504
2 - - 20.0
505
2 - - 22.8
486
2 - - 1.1
555
2 - - 23.7
579
2 - - 0.0
536
2 - - 8.7
588
2 - - 0.0
592
2 - - 39.6
554
2 - - 22.1
580
2 - - 0.0
526
2 - - 0.0
461
2 - - 20.9
476
2 - - 7.0
493
2 - - 7.9
519
2 - - 0.0
565
2 - - 7.9
578
2 - - 0.0
589
2 - - 0.0
564
2 - - 7.9
570
2 - - 5.9
451
2 - - 0.0
556
2 - - 4.4
534
2 - - 0.0
535
2 - - 0.0
525
2 - - 9.4
524
2 - - 9.3
543
2 - - 29.5
450
2 - - 8.0
571
2 - - 0.0
484
2 - - 0.0
458
2 - - 9.5
469
2 - - 37.4
506
2 - - 14.1
485
2 - - 0.0
521
2 - - 10.0
509
2 - - 43.1
466
2 - - 29.0
542
2 - - 30.0
531
2 - - 0.0
560
2 - - 4.4
481
2 - - 0.0
574
2 - - 0.0
575
2 - - 0.0
547
2 - - 39.8
559
2 - - 0.0
568
2 - - 0.0
497
2 - - 0.0
528
2 - - 6.6
530
2 - - 2.0
520
2 - - 4.4
586
2 - - 9.8
538
2 - - 0.0
488
2 - - 0.0
454
2 - - 3.0
492
2 - - 0.0
455
2 - - 0.7
479
2 - - 9.6
561
2 - - 0.8
480
2 - - 10.2
529
2 - - 0.0
501
2 - - 45.2
539
2 - - 0.0
576
2 - - 0.0
593
2 - - 40.7
489
2 - - 4.3
464
2 - - 2.1
465
2 - - 30.4
478
2 - - 0.0
470
2 - - 38.4
551
2 - - 20.7
602
2 - - 45.2
508
2 - - 43.8
514
2 - - 0.0
456
2 - - 12.2
515
2 - - 0.0
500
2 - - 0.0
471
2 - - 39.8
550
2 - - 14.5
584
2 - - 0.0
558
2 - - 0.0
569
2 - - 0.0
527
2 - - 0.0
482
2 - - 0.0
498
2 - - 0.8
490
2 - - 0.0
537
2 - - 11.3
522
2 - - 0.0
487
2 - - 0.0
596
2 - - 41.8
532
2 - - 1.8
573
2 - - 39.2
541
2 - - 0.0
446
2 - - 36.0
491
2 - - 0.0
562
2 - - 6.3
540
2 - - 11.4
453
2 - - 1.2
548
2 - - 43.0
567
2 - - 5.0
507
2 - - 29.6
552
2 - - 23.1
594
2 - - 37.8
601
2 - - 47.0
595
2 - - 36.1
502
2 - - 18.1
463
2 - - 8.6
557
2 - - 3.1
549
2 - - 43.1
472
2 - - 40.4
600
2 - - 41.9
513
2 - - 7.4
499
2 - - 43.7
445
2 - - 20.2
477
2 - - 0.0
583
2 - - 2.2
611
1 - - 0.0
746
1 - - 0.0
791
1 - - 0.0
666
1 - - 0.0
703
1 - - 0.0
753
1 - - 0.0
681
1 - - 0.0
604
1 - - 0.0
782
1 - - 0.0
833
1 - - 0.0
618
1 - - 0.0
798
1 - - 0.0
605
1 - - 0.0
697
1 - - 0.0
610
1 - - 0.0
717
1 - - 0.0
823
1 - - 0.0
790
1 - - 0.0
626
1 - - 0.0
787
1 - - 0.0
680
1 - - 0.0
679
1 - - 0.0
655
1 - - 0.0
654
1 - - 0.0
692
1 - - 0.0
712
1 - - 0.0
636
1 - - 0.0
688
1 - - 0.0
619
1 - - 0.0
799
1 - - 0.0
733
1 - - 0.0
772
1 - - 0.0
723
1 - - 0.0
817
1 - - 0.0
744
1 - - 0.0
670
1 - - 0.0
745
1 - - 0.0
777
1 - - 0.0
678
1 - - 0.0
812
1 - - 0.0
665
1 - - 0.0
664
1 - - 0.0
689
1 - - 0.0
625
1 - - 0.0
624
1 - - 0.0
634
1 - - 0.0
803
1 - - 0.0
656
1 - - 0.0
635
1 - - 0.0
763
1 - - 0.0
606
1 - - 0.0
671
1 - - 0.0
643
1 - - 0.0
690
1 - - 0.0
617
1 - - 0.0
710
1 - - 0.0
797
1 - - 0.0
698
1 - - 0.0
682
1 - - 0.0
718
1 - - 0.0
704
1 - - 0.0
819
1 - - 0.0
705
1 - - 0.0
755
1 - - 0.0
779
1 - - 0.0
612
1 - - 0.0
788
1 - - 0.0
736
1 - - 0.0
754
1 - - 0.0
792
1 - - 0.0
780
1 - - 0.0
687
1 - - 0.0
726
1 - - 0.0
766
1 - - 0.0
835
1 - - 0.0
834
1 - - 0.0
824
1 - - 0.0
691
1 - - 0.0
825
1 - - 0.0
646
1 - - 0.0
711
1 - - 0.0
781
1 - - 0.0
653
1 - - 0.0
806
1 - - 0.0
756
1 - - 0.0
734
1 - - 0.0
735
1 - - 0.0
811
1 - - 0.0
725
1 - - 0.0
724
1 - - 0.0
743
1 - - 0.0
771
1 - - 0.0
663
1 - - 0.0
706
1 - - 0.0
810
1 - - 0.0
623
1 - - 0.0
699
1 - - 0.0
805
1 - - 0.0
719
1 - - 0.0
804
1 - - 0.0
818
1 - - 0.0
672
1 - - 0.0
633
1 - - 0.0
765
1 - - 0.0
778
1 - - 0.0
836
1 - - 0.0
789
1 - - 0.0
764
1 - - 0.0
644
1 - - 0.0
677
1 - - 0.0
826
1 - - 0.0
770
1 - - 0.0
645
1 - - 0.0
801
1 - - 0.0
829
1 - - 0.0
637
1 - - 0.0
728
1 - - 0.0
730
1 - - 0.0
720
1 - - 0.0
627
1 - - 0.0
786
1 - - 0.0
738
1 - - 0.0
641
1 - - 0.0
673
1 - - 0.0
632
1 - - 0.0
716
1 - - 0.0
696
1 - - 0.0
622
1 - - 0.0
761
1 - - 0.0
662
1 - - 0.0
721
1 - - 0.0
815
1 - - 0.0
709
1 - - 0.0
814
1 - - 0.0
808
1 - - 0.0
800
1 - - 0.0
742
1 - - 0.0
731
1 - - 0.0
667
1 - - 0.0
648
1 - - 0.0
760
1 - - 0.0
774
1 - - 0.0
775
1 - - 0.0
640
1 - - 0.0
747
1 - - 0.0
759
1 - - 0.0
768
1 - - 0.0
694
1 - - 0.0
652
1 - - 0.0
708
1 - - 0.0
714
1 - - 0.0
809
1 - - 0.0
715
1 - - 0.0
695
1 - - 0.0
821
1 - - 0.0
831
1 - - 0.0
607
1 - - 0.0
700
1 - - 0.0
649
1 - - 0.0
657
1 - - 0.0
750
1 - - 0.0
785
1 - - 0.0
784
1 - - 0.0
758
1 - - 0.0
769
1 - - 0.0
830
1 - - 0.0
828
1 - - 0.0
729
1 - - 0.0
701
1 - - 0.0
739
1 - - 0.0
776
1 - - 0.0
613
1 - - 0.0
820
1 - - 0.0
793
1 - - 0.0
816
1 - - 0.0
683
1 - - 0.0
751
1 - - 0.0
807
1 - - 0.0
631
1 - - 0.0
642
1 - - 0.0
609
1 - - 0.0
762
1 - - 0.0
621
1 - - 0.0
674
1 - - 0.0
802
1 - - 0.0
659
1 - - 0.0
668
1 - - 0.0
647
1 - - 0.0
675
1 - - 0.0
740
1 - - 0.0
660
1 - - 0.0
748
1 - - 0.0
767
1 - - 0.0
813
1 - - 0.0
638
1 - - 0.0
727
1 - - 0.0
686
1 - - 0.0
620
1 - - 0.0
630
1 - - 0.0
628
1 - - 0.0
737
1 - - 0.0
722
1 - - 0.0
661
1 - - 0.0
796
1 - - 0.0
732
1 - - 0.0
773
1 - - 0.0
616
1 - - 0.0
741
1 - - 0.0
639
1 - - 0.0
693
1 - - 0.0
827
1 - - 0.0
676
1 - - 0.0
713
1 - - 0.0
837
1 - - 0.0
629
1 - - 0.0
651
1 - - 0.0
822
1 - - 0.0
783
1 - - 0.0
832
Crp/Fnr family
1 - - 0.0
707
1 - - 0.0
614
1 - - 0.0
608
1 - - 0.0
752
1 - - 0.0
794
1 - - 0.0
795
1 - - 0.0
615
1 - - 0.0
685
1 - - 0.0
658
1 - - 0.0
669
1 - - 0.0
702
1 - - 0.0
684
1 - - 0.0
650
1 - - 0.0
757
1 - - 0.0
749
1 - - 0.0
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