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CATH Superfamily 2.40.50.140

Nucleic acid-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23: Polyribonucleotide nucleotidyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 30 P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI)
(20 more)
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
 20 P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(10 more)
Polyribonucleotide nucleotidyltransferase activity GO:0004654
Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
 20 P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(10 more)
Polyribonucleotide nucleotidyltransferase activity GO:0004654
Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
 20 Q3Z7V6 (/ISS) Q609C6 (/ISS) Q71ZZ1 (/ISS) Q71ZZ1 (/ISS) Q71ZZ1 (/ISS) Q71ZZ1 (/ISS) Q74CS9 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS)
(10 more)
Cyclic-di-GMP binding GO:0035438
Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate.
 20 P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(10 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 20 P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI) P05055 (/IPI)
(10 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
 6 Q3Z7V6 (/ISS) Q74CS9 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS) Q8EHL1 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
 20 P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP) P05055 (/IMP)
(10 more)
RNA catabolic process GO:0006401
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
 10 Q609C6 (/ISS) Q83D87 (/ISS) Q83D87 (/ISS) Q83D87 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS) Q9KU76 (/ISS)
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
 10 Q3Z7V6 (/ISS) Q71ZZ1 (/ISS) Q71ZZ1 (/ISS) Q71ZZ1 (/ISS) Q71ZZ1 (/ISS) Q74CS9 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS) Q81WM8 (/ISS) Q8EHL1 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 20 P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA)
(10 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 20 P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA) P05055 (/IDA)
(10 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 20 P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA) P05055 (/HDA)
(10 more)