The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Acetyl-CoA carboxylase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 31 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
8 H2L0M0 (/ISS) P32874 (/ISS) Q13085 (/ISS) Q28559 (/ISS) Q38970 (/ISS) Q7KQ29 (/ISS) Q9GZI3 (/ISS) Q9TTS3 (/ISS)
Biotin binding GO:0009374
Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
7 A0A0G2K1F2 (/IDA) A0A0G2K5L6 (/IDA) D3ZBE2 (/IDA) E9PSQ0 (/IDA) O70151 (/IDA) P11029 (/IDA) P11497 (/IDA)
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
6 E9Q4Z2 (/IDA) O00763 (/IDA) P11029 (/IDA) P11497 (/IDA) Q39478 (/IDA) Q5SWU9 (/IDA)
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
6 B7G7S4 (/IMP) E9Q4Z2 (/IMP) F4I1L3 (/IMP) Q00955 (/IMP) Q00955 (/IMP) Q5SWU9 (/IMP)
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
5 G5EAT9 (/ISA) G5EAT9 (/ISA) G5EAT9 (/ISA) Q4Q5W1 (/ISA) Q57YR7 (/ISA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 O00763 (/IPI) Q00955 (/IPI) Q00955 (/IPI) Q13085 (/IPI)
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
3 E9Q4Z2 (/ISO) P78820 (/ISO) Q5SWU9 (/ISO)
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
3 G5EAT9 (/RCA) G5EAT9 (/RCA) G5EAT9 (/RCA)
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
3 G5EAT9 (/RCA) G5EAT9 (/RCA) G5EAT9 (/RCA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 O00763 (/IPI) Q13085 (/IPI) Q5SWU9 (/IPI)
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
2 P11029 (/TAS) Q13085 (/TAS)
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
2 Q00955 (/IMP) Q00955 (/IMP)
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
2 Q4Q5W1 (/ISM) Q57YR7 (/ISM)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 P11029 (/IDA) Q57YR7 (/IDA)
Biotin binding GO:0009374
Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
2 E9Q4Z2 (/ISO) Q5SWU9 (/ISO)
Carboxyl- or carbamoyltransferase activity GO:0016743
Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).
2 Q00955 (/IMP) Q00955 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 E9Q4Z2 (/ISO) Q5SWU9 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q00955 (/IMP) Q00955 (/IMP)
Acetyl-CoA binding GO:1905502
Interacting selectively and non-covalently with acetyl-CoA.
2 Q00955 (/IMP) Q00955 (/IMP)
Acetyl-CoA carboxylase activity GO:0003989
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
1 P32874 (/IGI)
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
1 P11029 (/IDA)
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
1 P78820 (/ISO)
Biotin carboxylase activity GO:0004075
Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
1 Q54J08 (/ISS)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 P11029 (/TAS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q4Q5W1 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 P78820 (/ISS)
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
1 Q54J08 (/HDA)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
1 Q5SWU9 (/ISO)
Sterol response element binding GO:0032810
Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.
1 P11029 (/TAS)
Thyroid hormone receptor binding GO:0046966
Interacting selectively and non-covalently with a thyroid hormone receptor.
1 P11029 (/TAS)
DBD domain binding GO:0050692
Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
1 P11029 (/IDA)

There are 73 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
6 A0A0G2K1F2 (/IMP) A0A0G2K5L6 (/IMP) D3ZBE2 (/IMP) E9PSQ0 (/IMP) O70151 (/IMP) P11497 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
6 A0A0G2K1F2 (/IEP) A0A0G2K5L6 (/IEP) D3ZBE2 (/IEP) E9PSQ0 (/IEP) O70151 (/IEP) P11497 (/IEP)
Response to (R)-carnitine GO:0061959
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.
5 A0A2R8QJA0 (/IEP) A0A2R8QPK9 (/IEP) A0A2R8RIG4 (/IEP) F1QH12 (/IEP) F6P055 (/IEP)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
4 E9Q4Z2 (/IMP) H2L0M0 (/IMP) Q7KQ29 (/IMP) Q9GZI3 (/IMP)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
4 Q13085 (/ISS) Q28559 (/ISS) Q54J08 (/ISS) Q9TTS3 (/ISS)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
4 P11497 (/ISS) Q13085 (/ISS) Q28559 (/ISS) Q9TTS3 (/ISS)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
3 A1Z784 (/IMP) A8DY67 (/IMP) Q7JV23 (/IMP)
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
3 H2L0M0 (/IMP) Q7KQ29 (/IMP) Q9GZI3 (/IMP)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
3 A1Z784 (/IMP) A8DY67 (/IMP) Q7JV23 (/IMP)
Acetyl-CoA metabolic process GO:0006084
The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
3 Q13085 (/ISS) Q28559 (/ISS) Q9TTS3 (/ISS)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
3 P11029 (/IDA) P11497 (/IDA) Q5SWU9 (/IDA)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
3 G5EAT9 (/ISA) G5EAT9 (/ISA) G5EAT9 (/ISA)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
3 G5EAT9 (/RCA) G5EAT9 (/RCA) G5EAT9 (/RCA)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
3 A1Z784 (/IMP) A8DY67 (/IMP) Q7JV23 (/IMP)
Polarity specification of anterior/posterior axis GO:0009949
Any process resulting in the establishment of polarity along the anterior/posterior axis.
3 H2L0M0 (/IMP) Q7KQ29 (/IMP) Q9GZI3 (/IMP)
Triglyceride biosynthetic process GO:0019432
The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.
3 A1Z784 (/IMP) A8DY67 (/IMP) Q7JV23 (/IMP)
Water homeostasis GO:0030104
Any process involved in the maintenance of an internal steady state of water within an organism or cell.
3 H2L0M0 (/IMP) Q7KQ29 (/IMP) Q9GZI3 (/IMP)
Cellular response to sucrose stimulus GO:0071329
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
3 A1Z784 (/IDA) A8DY67 (/IDA) Q7JV23 (/IDA)
Acetyl-CoA metabolic process GO:0006084
The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
2 O00763 (/IDA) Q5SWU9 (/IDA)
Acetyl-CoA biosynthetic process GO:0006085
The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
2 Q00955 (/IMP) Q00955 (/IMP)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
2 Q00955 (/IMP) Q00955 (/IMP)
Carnitine shuttle GO:0006853
The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine.
2 O00763 (/TAS) Q13085 (/TAS)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 E9Q4Z2 (/ISO) Q5SWU9 (/ISO)
Positive regulation of cellular metabolic process GO:0031325
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
2 O00763 (/TAS) Q13085 (/TAS)
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
2 Q00955 (/IMP) Q00955 (/IMP)
Regulation of cholesterol biosynthetic process GO:0045540
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
2 O00763 (/TAS) Q13085 (/TAS)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
2 O00763 (/IDA) Q5SWU9 (/IDA)
Tissue homeostasis GO:0001894
A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.
1 Q5SWU9 (/IMP)
Acetyl-CoA metabolic process GO:0006084
The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
1 E9Q4Z2 (/ISO)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
1 Q54J08 (/ISS)
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
1 Q5SWU9 (/IMP)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 Q57YR7 (/ISM)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 Q5SWU9 (/ISO)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1 P11029 (/TAS)
Transport GO:0006810
The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
1 P11029 (/TAS)
Quorum sensing GO:0009372
The process in which single-celled organisms monitor their population density by detecting the concentration of small, diffusible signal molecules produced by the cells themselves.
1 Q57YR7 (/IDA)
Quorum sensing GO:0009372
The process in which single-celled organisms monitor their population density by detecting the concentration of small, diffusible signal molecules produced by the cells themselves.
1 Q4Q5W1 (/ISO)
Response to cytokinin GO:0009735
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
1 Q38970 (/IMP)
Response to carbohydrate GO:0009743
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
1 P11029 (/IDA)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
1 Q38970 (/IMP)
Meristem structural organization GO:0009933
Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.
1 Q38970 (/IMP)
Primary shoot apical meristem specification GO:0010072
The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.
1 Q38970 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 P11029 (/IDA)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 E9Q4Z2 (/IMP)
Positive regulation of lipid storage GO:0010884
Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
1 E9Q4Z2 (/IMP)
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
1 E9Q4Z2 (/IMP)
Protein metabolic process GO:0019538
The chemical reactions and pathways involving a protein. Includes protein modification.
1 Q5SWU9 (/IMP)
Fatty acid elongation GO:0030497
The elongation of a fatty acid chain by the sequential addition of two-carbon units.
1 Q57YR7 (/IDA)
Fatty acid elongation GO:0030497
The elongation of a fatty acid chain by the sequential addition of two-carbon units.
1 Q38970 (/IMP)
Fatty acid elongation GO:0030497
The elongation of a fatty acid chain by the sequential addition of two-carbon units.
1 Q4Q5W1 (/ISO)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
1 E9Q4Z2 (/IMP)
Negative regulation of fatty acid beta-oxidation GO:0031999
Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.
1 E9Q4Z2 (/IMP)
Regulation of gene expression, epigenetic GO:0040029
Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
1 P11029 (/IDA)
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
1 P32874 (/IGI)
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
1 E9Q4Z2 (/IDA)
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
1 Q9GZI3 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P11029 (/IMP)
Negative regulation of fatty acid oxidation GO:0046322
Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.
1 E9Q4Z2 (/IMP)
Fatty-acyl-CoA biosynthetic process GO:0046949
The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
1 Q13085 (/TAS)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
1 Q38970 (/IMP)
Shoot system development GO:0048367
The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.
1 Q38970 (/IMP)
Negative regulation of lipid catabolic process GO:0050995
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
1 E9Q4Z2 (/IMP)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 E9Q4Z2 (/ISO)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
1 Q5SWU9 (/IMP)
Positive regulation of heart growth GO:0060421
Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
1 E9Q4Z2 (/IMP)
Regulation of biological quality GO:0065008
Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
1 P11029 (/IDA)
Response to fatty acid GO:0070542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
1 P11029 (/TAS)
Cellular response to prostaglandin E stimulus GO:0071380
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
1 Q5SWU9 (/IDA)
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
1 E9Q4Z2 (/IMP)
Response to thyroid hormone GO:0097066
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
1 P11029 (/IDA)
Malonyl-CoA biosynthetic process GO:2001295
The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.
1 P11029 (/IDA)
Malonyl-CoA biosynthetic process GO:2001295
The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.
1 E9Q4Z2 (/IMP)
Malonyl-CoA biosynthetic process GO:2001295
The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.
1 P11029 (/TAS)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 A0A0G2K1F2 (/IDA) A0A0G2K5L6 (/IDA) D3ZBE2 (/IDA) E9PSQ0 (/IDA) E9Q4Z2 (/IDA) O00763 (/IDA) O70151 (/IDA) P32874 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 E9Q4Z2 (/HDA) P32874 (/HDA) Q00955 (/HDA) Q00955 (/HDA) Q5SWU9 (/HDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
4 G1N7J4 (/ISS) G3US43 (/ISS) H0ZD19 (/ISS) U3IH42 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 A1Z784 (/IDA) A8DY67 (/IDA) Q57YR7 (/IDA) Q7JV23 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
4 H2L0M0 (/ISS) Q54J08 (/ISS) Q7KQ29 (/ISS) Q9GZI3 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P11497 (/ISS) Q13085 (/ISS) Q28559 (/ISS) Q9TTS3 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P78820 (/HDA) Q00955 (/HDA) Q00955 (/HDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 F1NWT0 (/IDA) P11029 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P32874 (/HDA) P78820 (/HDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 Q00955 (/IDA) Q00955 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q13085 (/IDA) Q5SWU9 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O00763 (/TAS) Q13085 (/TAS)
Acetyl-CoA carboxylase complex GO:0009317
A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.
2 Q00955 (/IMP) Q00955 (/IMP)
Biotin carboxylase complex GO:0009343
An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2).
2 Q4Q5W1 (/ISM) Q57YR7 (/ISM)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
1 P78820 (/HDA)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
1 Q13085 (/IDA)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
1 Q5SWU9 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O00763 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 E9Q4Z2 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4Q5W1 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P11029 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q57YR7 (/ISM)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 E9Q4Z2 (/ISO)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
1 O00763 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q5SWU9 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q38970 (/IDA)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
1 Q13085 (/IDA)
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
1 Q5SWU9 (/ISO)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 Q57YR7 (/IDA)
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
1 Q4Q5W1 (/ISO)