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CATH Superfamily 2.40.50.100

RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: DNA-directed RNA polymerase subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 129 P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI) P0A8T7 (/IPI)
(119 more)
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
 7 Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
 7 Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS) Q9KV29 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 129 P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA)
(119 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 129 P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA) P0A8T7 (/IDA)
(119 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 129 P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA) P0A8T7 (/HDA)
(119 more)