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CATH Superfamily 2.40.50.100

RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 50S ribosomal protein L27

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
 189 O67650 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA)
(179 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
 188 P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA)
(178 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 188 P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI) P0A7L8 (/IPI)
(178 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
 11 Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS)
(1 more)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal large subunit assembly GO:0000027
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
 189 O67650 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA)
(179 more)
Ribosomal large subunit assembly GO:0000027
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
 188 P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI)
(178 more)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
 188 P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI)
(178 more)
Mature ribosome assembly GO:0042256
The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
 188 P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP) P0A7L8 (/IMP)
(178 more)
Positive regulation of ribosome biogenesis GO:0090070
Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
 188 P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI)
(178 more)
Assembly of large subunit precursor of preribosome GO:1902626
The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.
 188 P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI) P0A7L8 (/IGI)
(178 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
 11 Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS)
(1 more)
Assembly of large subunit precursor of preribosome GO:1902626
The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.
 1 O67650 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
 189 O67650 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA) P0A7L8 (/IDA)
(179 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
 11 Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS) Q9KUS9 (/ISS)
(1 more)