The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Translation factors
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
3327
3D
4r71C04 - 89.5
2
3197
3D
4r71C05 - 83.1
3
2709
3D
5o8wA02 - 91.5
4
2218 - - 97.5
5
1856
3D
5o8wA03 - 87.3
6
1650
3D
2efgA02 - 96.0
7
1410 - - 96.9
8
1335
3D
1d1nA00 - 94.3
9
1119
3D
3j81k02 - 99.4
10
988
3D
3b8hE03 - 89.0
11
927
3D
4zgqB00 - 93.0
12
900
3D
5an9A02 - 90.5
13
856
3D
4ncfB02 - 94.3
14
818 - - 93.3
15
779
3D
3cb4F02 - 96.7
16
756
3D
4zcmB02 - 92.9
17
735
3D
3e20J02 - 94.6
18
+
624
3D
1a8pA01 - 75.7
19
562 - - 92.2
20
555
3D
3mcaA01 - 86.9
21
540
3D
1umkA01 - 92.0
22
519 - - 94.0
23
505
3D
2deuB03 - 96.2
24
493
3D
5hxbX01 - 88.1
25
457
3D
1tllB03 - 92.4
26
449
3D
3wbkB04 - 97.5
27
417
3D
1zunB02 - 89.3
28
353 - - 73.7
29
348 - - 98.3
30
296 - - 86.7
36
293
3D
3fjoA03 - 82.2
31
293
3D
1zunB03 - 90.9
34
280
3D
1gvhA02 - 97.0
32
279
3D
2eixB01 - 93.1
33
265 - - 62.6
35
241 - - 94.9
37
234 - - 84.0
38
232
3D
1ddiA01 - 93.0
39
228 - - 71.5
40
228 - - 86.8
41
203
3D
5gxuB01 - 71.8
42
NAD
P
196
3D
1qfjD01 - 16.7
43
181 - - 70.4
48
177
3D
3lvbA01 - 79.0
44
+
177
3D
2xnjB01 - 57.1
45
NAD(+
144 - - 53.9
46
140 - - 76.4
47
137 - - 82.2
49
128 - - 84.8
50
127 - - 32.3
51
125 - - 91.9
75
123
3D
6i5mA03 - 97.5
54
123
3D
4kjzD03 - 99.3
52
120 - - 89.8
53
119 - - 75.4
55
111 - - 73.2
56
103 - - 88.1
57
101 - - 73.3
58
100 - - 32.6
59
96 - - 91.7
60
94 - - 85.7
62
92
3D
2qtzA02 - 61.8
61
92 - - 85.0
63
89 - - 91.8
64
Na
+
89
3D
4u9uB01 - 54.7
65
85 - - 80.7
68
82
3D
1xb2A02 - 68.2
70
80
3D
3p27B03 - 99.8
71
79
3D
1xb2A03 - 72.7
66
78 - - 86.9
67
78 - - 87.9
69
77 - - 98.0
73
76
3D
2bpoB03 - 68.2
72
73
3D
2crvA01 - 83.9
74
64 - - 0.0
76
63 - - 78.1
77
60 - - 73.6
79
58 - - 83.9
78
58 - - 44.8
80
57 - - 67.2
81
P
55 - - 25.0
82
55 - - 90.1
83
53 - - 74.4
85
50 - - 91.6
84
50 - - 85.7
86
49 - - 77.0
87
P
47 - - 19.5
90
43 - - 88.9
89
43 - - 19.7
88
43 - - 20.0
91
NoxA
40 - - 87.0
92
39 - - 82.0
93
37 - - 79.3
199
36
3D
4bprA01 - 22.8
94
33 - - 24.0
95
33 - - 72.1
96
32 - - 61.1
97
31 - - 55.0
98
30 - - 79.4
99
30 - - 89.7
100
29 - - 85.7
101
28 - - 20.5
102
27 - - 94.4
104
24 - - 5.3
103
24 - - 64.6
105
24 - - 67.1
107
23 - - 83.1
106
23 - - 81.2
108
23 - - 81.2
110
22 - - 72.4
109
22 - - 70.4
111
21 - - 79.8
113
21 - - 93.6
114
21 - - 96.4
112
21 - - 13.2
130
21
3D
4dqlB01 - 69.8
115
20 - - 87.8
118
19 - - 5.3
119
19 - - 67.4
117
19 - - 3.2
116
19 - - 12.6
121
19 - - 82.2
120
19 - - 76.2
126
18 - - 87.4
127
18 - - 95.6
122
18 - - 69.6
124
18 - - 33.1
123
18 - - 24.5
125
18 - - 80.8
134
17 - - 74.1
132
17 - - 3.7
129
17 - - 0.9
128
17 - - 11.1
135
17 - - 0.0
131
17 - - 57.9
133
17 - - 44.5
139
16 - - 9.0
136
16 - - 0.0
144
16 - - 67.3
142
16 - - 5.8
137
16 - - 1.6
143
16 - - 7.6
165
16
3D
3p27B02 - 46.5
138
16 - - 17.6
141
16 - - 4.5
140
16 - - 6.4
146
15 - - 24.7
150
15 - - 11.6
147
15 - - 9.1
151
15 - - 84.0
153
15 - - 0.0
149
15 - - 8.0
148
15 - - 18.0
152
15 - - 74.3
145
15 - - 66.2
155
14 - - 46.4
158
14 - - 91.2
159
14 - - 88.6
154
14 - - 81.0
168
14
3D
4c0sB02 - 71.8
156
14 - - 46.5
157
14 - - 4.4
162
13 - - 22.5
164
13 - - 0.0
160
13 - - 2.6
161
13 - - 28.5
163
13 - - 12.1
169
12 - - 62.9
166
12 - - 42.7
167
12 - - 43.5
175
11 - - 27.8
170
11 - - 39.6
171
11 - - 10.4
173
11 - - 11.3
172
11 - - 10.6
174
11 - - 0.0
176
11 - - 20.9
184
10 - - 4.8
182
10 - - 43.5
351
10 - - 53.5
187
10 - - 49.5
178
10 - - 29.2
186
10 - - 0.0
180
10 - - 85.8
181
10 - - 14.5
185
P
10 - - 17.7
179
10 - - 16.4
188
10 - - 59.1
183
10 - - 60.6
177
10 - - 39.9
189
9 - - 0.0
194
9 - - 1.5
192
9 - - 0.0
190
9 - - 33.3
191
9 - - 0.0
195
9 - - 55.2
193
9 - - 7.7
202
8 - - 2.8
204
8 - - 0.0
196
8 - - 43.2
197
8 - - 24.5
200
8 - - 13.5
201
8 - - 2.6
205
8 - - 12.2
198
8 - - 87.9
203
8 - - 39.6
209
7 - - 37.0
218
NAD
P
7 - - 0.0
213
7 - - 4.2
224
7 - - 67.0
222
7 - - 48.3
211
7 - - 8.3
207
7 - - 11.2
210
7 - - 1.1
226
7 - - 65.5
215
7 - - 15.6
206
7 - - 41.3
227
7 - - 48.7
217
7 - - 36.9
225
7 - - 77.1
216
7 - - 9.0
220
7 - - 4.9
221
7 - - 39.2
223
7 - - 52.2
212
7 - - 4.7
214
7 - - 41.2
219
7 - - 20.3
208
7 - - 38.1
236
6 - - 5.5
229
6 - - 10.1
237
6 - - 1.4
242
6 - - 88.5
239
TuF-2
6 - - 50.4
232
6 - - 79.4
234
6 - - 0.9
233
6 - - 34.3
238
6 - - 35.9
240
6 - - 36.9
241
6 - - 79.9
243
6 - - 20.8
228
6 - - 4.9
235
6 - - 14.6
230
6 - - 5.7
231
methionine synthase
6 - - 76.1
253
5 - - 0.0
258
5 - - 57.9
249
5 - - 47.7
244
5 - - 0.0
246
5 - - 13.0
255
5 - - 9.6
264
5 - - 85.7
251
5 - - 12.3
262
5 - - 13.3
247
5 - - 74.6
250
5 - - 9.5
263
5 - - 55.8
256
5 - - 0.0
245
5 - - 2.5
257
5 - - 0.0
248
5 - - 9.8
259
IF-2
5 - - 10.5
265
5 - - 18.5
252
5 - - 4.9
254
5 - - 78.8
261
5 - - 1.5
260
5 - - 0.0
287
4 - - 31.7
273
4 - - 8.6
278
4 - - 1.7
266
4 - - 3.4
286
4 - - 60.7
267
4 - - 3.1
282
4 - - 10.3
284
4 - - 6.0
289
4 - - 17.8
292
4 - - 37.8
269
4 - - 59.8
275
4 - - 1.2
271
4 - - 5.4
270
4 - - 17.3
268
4 - - 31.6
276
4 - - 3.4
288
4 - - 45.7
277
4 - - 1.1
283
4 - - 11.6
281
4 - - 75.7
280
4 - - 37.7
285
4 - - 15.4
291
4 - - 82.2
290
4 - - 52.6
279
4 - - 32.0
274
4 - - 4.7
272
4 - - 9.8
306
3 - - 15.4
296
3 - - 10.4
311
3 - - 8.8
297
3 - - 7.4
307
3 - - 14.3
310
3 - - 10.1
315
3 - - 31.3
318
3 - - 31.9
313
3 - - 11.4
294
3 - - 14.5
302
3 - - 6.0
304
3 - - 10.0
309
3 - - 6.7
299
3 - - 0.0
308
3 - - 85.1
298
3 - - 10.2
303
3 - - 0.0
293
4,6
3 - - 0.0
312
3 - - 0.0
314
3 - - 31.7
319
3 - - 1.4
316
3 - - 0.0
320
3 - - 1.3
321
3 - - 13.5
317
3 - - 12.1
300
3 - - 9.4
301
3 - - 0.0
305
3 - - 2.0
295
3 - - 0.0
392
2 - - 0.0
339
2 - - 0.0
394
2 - - 0.0
355
2 - - 8.5
375
2 - - 0.0
369
2 - - 18.2
364
2 - - 1.8
362
2 - - 0.0
371
2 - - 9.9
332
2 - - 8.1
347
2 - - 0.0
350
2 - - 36.3
399
+
2 - - 45.2
334
2 - - 0.0
370
2 - - 0.0
327
2 - - 0.0
382
2 - - 9.7
384
2 - - 0.0
346
2 - - 2.5
326
2 - - 8.1
389
2 - - 4.7
329
2 - - 9.0
349
2 - - 21.4
397
P
2 - - 43.0
386
2 - - 0.0
367
2 - - 2.7
342
2 - - 0.0
337
2 - - 0.0
344
2 - - 9.5
324
2 - - 0.0
322
2 - - 2.6
387
2 - - 2.0
353
2 - - 50.2
396
2 - - 39.7
373
2 - - 7.3
336
2 - - 0.0
400
2 - - 46.9
378
2 - - 6.6
358
2 - - 1.2
366
2 - - 0.0
401
2 - - 45.8
335
2 - - 6.2
391
2 - - 0.0
390
2 - - 1.0
359
2 - - 0.0
379
2 - - 7.5
365
2 - - 0.0
352
2 - - 42.0
374
2 - - 0.0
330
2 - - 0.0
354
2 - - 48.1
372
2 - - 10.9
361
2 - - 6.3
395
2 - - 31.2
331
2 - - 5.5
360
2 - - 8.6
381
2 - - 0.0
323
2 - - 10.3
343
2 - - 10.8
380
2 - - 0.0
348
2 - - 26.0
328
NAD(+
2 - - 0.0
385
2 - - 0.0
325
2 - - 18.4
345
2 - - 5.5
388
2 - - 2.8
340
2 - - 0.0
357
2 - - 3.4
377
2 - - 27.2
341
2 - - 0.0
383
2 - - 5.1
333
2 - - 0.0
398
2 - - 45.8
363
2 - - 0.0
338
2 - - 0.0
393
2 - - 2.1
368
2 - - 0.0
356
2 - - 1.1
376
2 - - 2.3
461
1 - - 0.0
472
1 - - 0.0
454
1 - - 0.0
403
1 - - 0.0
474
1 - - 0.0
430
1 - - 0.0
452
1 - - 0.0
501
1 - - 0.0
460
1 - - 0.0
495
1 - - 0.0
431
1 - - 0.0
500
1 - - 0.0
517
1 - - 0.0
533
5-methylaminomethyl-2-thiouridylate
1 - - 0.0
408
1 - - 0.0
435
1 - - 0.0
491
1 - - 0.0
505
1 - - 0.0
465
1 - - 0.0
479
1 - - 0.0
459
1 - - 0.0
490
1 - - 0.0
448
1 - - 0.0
516
1 - - 0.0
428
1 - - 0.0
525
1 - - 0.0
419
1 - - 0.0
485
1 - - 0.0
423
1 - - 0.0
481
1 - - 0.0
414
1 - - 0.0
443
1 - - 0.0
412
1 - - 0.0
521
1 - - 0.0
480
1 - - 0.0
520
1 - - 0.0
477
1 - - 0.0
457
1 - - 0.0
440
1 - - 0.0
420
1 - - 0.0
441
1 - - 0.0
523
1 - - 0.0
421
1 - - 0.0
512
1 - - 0.0
514
1 - - 0.0
483
1 - - 0.0
425
1 - - 0.0
519
1 - - 0.0
445
1 - - 0.0
488
1 - - 0.0
528
1 - - 0.0
416
1 - - 0.0
438
1 - - 0.0
405
1 - - 0.0
476
1 - - 0.0
456
1 - - 0.0
468
1 - - 0.0
493
1 - - 0.0
508
1 - - 0.0
531
1 - - 0.0
417
1 - - 0.0
433
1 - - 0.0
503
1 - - 0.0
530
1 - - 0.0
463
1 - - 0.0
498
1 - - 0.0
471
1 - - 0.0
462
1 - - 0.0
451
1 - - 0.0
464
1 - - 0.0
502
1 - - 0.0
504
1 - - 0.0
434
1 - - 0.0
470
1 - - 0.0
499
1 - - 0.0
450
1 - - 0.0
432
1 - - 0.0
447
1 - - 0.0
427
1 - - 0.0
494
1 - - 0.0
439
1 - - 0.0
492
1 - - 0.0
406
1 - - 0.0
509
1 - - 0.0
469
1 - - 0.0
475
1 - - 0.0
455
1 - - 0.0
446
1 - - 0.0
426
1 - - 0.0
518
1 - - 0.0
529
1 - - 0.0
415
1 - - 0.0
489
1 - - 0.0
513
1 - - 0.0
484
1 - - 0.0
482
1 - - 0.0
524
1 - - 0.0
522
1 - - 0.0
411
1 - - 0.0
410
1 - - 0.0
407
1 - - 0.0
467
1 - - 0.0
510
1 - - 0.0
507
1 - - 0.0
444
1 - - 0.0
442
1 - - 0.0
437
1 - - 0.0
413
1 - - 0.0
422
1 - - 0.0
511
1 - - 0.0
424
Fragment
1 - - 0.0
429
1 - - 0.0
515
1 - - 0.0
497
1 - - 0.0
449
1 - - 0.0
486
1 - - 0.0
418
1 - - 0.0
526
1 - - 0.0
436
1 - - 0.0
409
1 - - 0.0
466
1 - - 0.0
458
1 - - 0.0
478
1 - - 0.0
506
1 - - 0.0
532
1 - - 0.0
487
1 - - 0.0
534
1 - - 0.0
527
1 - - 0.0
404
1 - - 0.0
473
1 - - 0.0
402
1 - - 0.0
496
1 - - 0.0
453
1 - - 0.0
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