The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Major urinary protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Insulin-activated receptor activity GO:0005009
Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Pheromone binding GO:0005550
Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
11 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(1 more)
Odorant binding GO:0005549
Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell.
3 P08937 (/IDA) Q78E14 (/IDA) Q9D3H2 (/IDA)
Pheromone binding GO:0005550
Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
3 P11588 (/IDA) P11588 (/IDA) Q5FW60 (/IDA)
Insulin-activated receptor activity GO:0005009
Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity.
2 P11588 (/IDA) P11588 (/IDA)
Pheromone activity GO:0005186
The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant.
2 P11588 (/IDA) P11588 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P11590 (/IPI) P11590 (/IPI)
Odorant binding GO:0005549
Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell.
2 A0A0D3M039 (/ISO) Q9D3N5 (/ISO)
Odorant binding GO:0005549
Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell.
2 F8WFF8 (/TAS) Q9JJH9 (/TAS)
Mating pheromone activity GO:0000772
The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted.
1 Q5FW60 (/IDA)
Endopeptidase inhibitor activity GO:0004866
Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
1 Q9JJI1 (/NAS)

There are 37 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Energy reserve metabolic process GO:0006112
The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Negative regulation of lipid storage GO:0010888
Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Positive regulation of glucose metabolic process GO:0010907
Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Heat generation GO:0031649
Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Positive regulation of lipid metabolic process GO:0045834
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Negative regulation of lipid biosynthetic process GO:0051055
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179
Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Cellular response to lipid GO:0071396
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Cellular response to testosterone stimulus GO:0071394
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
4 P04938 (/IEP) P04938 (/IEP) P11588 (/IEP) P11588 (/IEP)
Response to stilbenoid GO:0035634
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.
3 P04939 (/IEP) P11588 (/IEP) P11588 (/IEP)
Energy reserve metabolic process GO:0006112
The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.
2 P11588 (/IDA) P11588 (/IDA)
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
2 P11588 (/IDA) P11588 (/IDA)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
2 P11588 (/IEP) P11588 (/IEP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P11588 (/IDA) P11588 (/IDA)
Negative regulation of lipid storage GO:0010888
Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
2 P11588 (/IDA) P11588 (/IDA)
Positive regulation of glucose metabolic process GO:0010907
Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
2 P11588 (/IDA) P11588 (/IDA)
Heat generation GO:0031649
Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
2 P11588 (/IDA) P11588 (/IDA)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
2 P11588 (/IMP) P11588 (/IMP)
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
2 P11588 (/IDA) P11588 (/IDA)
Negative regulation of gluconeogenesis GO:0045721
Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
2 P11588 (/IDA) P11588 (/IDA)
Positive regulation of lipid metabolic process GO:0045834
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
2 P11588 (/IDA) P11588 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 P11588 (/IDA) P11588 (/IDA)
Negative regulation of lipid biosynthetic process GO:0051055
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
2 P11588 (/IDA) P11588 (/IDA)
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
2 P11588 (/IDA) P11588 (/IDA)
Negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179
Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
2 P11588 (/IDA) P11588 (/IDA)
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
2 P11588 (/IDA) P11588 (/IDA)
Cellular response to food GO:0071240
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
2 P11588 (/IEP) P11588 (/IEP)
Cellular response to lipid GO:0071396
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
2 P11588 (/IDA) P11588 (/IDA)
Olfactory learning GO:0008355
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
1 Q5FW60 (/IDA)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
13 F0UZ12 (/IDA) H2B3G5 (/IDA) P02761 (/IDA) P04939 (/IDA) P11588 (/IDA) P11588 (/IDA) P11589 (/IDA) P11590 (/IDA) P11590 (/IDA) Q99MG7 (/IDA)
(3 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 P02761 (/ISS) P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS)
(2 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
11 P02762 (/ISS) P02762 (/ISS) P04938 (/ISS) P04938 (/ISS) P04939 (/ISS) P11589 (/ISS) P11590 (/ISS) P11590 (/ISS) P11591 (/ISS) Q5FW60 (/ISS)
(1 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
4 O08976 (/IDA) O08976 (/IDA) O08976 (/IDA) Q5FW60 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 F8WFF8 (/TAS) Q9JJH9 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P11588 (/IDA) P11588 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P11588 (/IDA) P11588 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9QXU1 (/IDA)
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