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CATH Superfamily 2.40.100.10

Cyclophilin-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cyclophilin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42: Multifunctional urea amidolyase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Allophanate hydrolase activity GO:0004039
Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+).
 4 A0A1D8PDC6 (/IMP) A0A1D8PDC6 (/IMP) P32528 (/IMP) P32528 (/IMP)
Urea carboxylase activity GO:0004847
Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate.
 4 A0A1D8PDC6 (/IMP) A0A1D8PDC6 (/IMP) P32528 (/IMP) P32528 (/IMP)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Urea catabolic process GO:0043419
The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
 4 A0A1D8PDC6 (/IMP) A0A1D8PDC6 (/IMP) P32528 (/IMP) P32528 (/IMP)
Allantoin catabolic process GO:0000256
The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
 2 P32528 (/TAS) P32528 (/TAS)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
 2 A0A1D8PDC6 (/IMP) A0A1D8PDC6 (/IMP)
Nitrogen utilization GO:0019740
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.
 2 A0A1D8PDC6 (/IMP) A0A1D8PDC6 (/IMP)
Cellular response to alkaline pH GO:0071469
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
 2 A0A1D8PDC6 (/IMP) A0A1D8PDC6 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 2 P32528 (/HDA) P32528 (/HDA)