The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Trypsin-like serine proteases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 475: Azurocidin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microglial cell activation GO:0001774
The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1 Q86SR2 (/ISS)
Glial cell migration GO:0008347
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
1 Q86SR2 (/ISS)
Antibacterial humoral response GO:0019731
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
1 Q86SR2 (/IDA)
Positive regulation of tumor necrosis factor biosynthetic process GO:0042535
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
1 Q86SR2 (/ISS)
Positive regulation of MHC class II biosynthetic process GO:0045348
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
1 Q86SR2 (/ISS)
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
1 Q86SR2 (/ISS)
Positive regulation of interleukin-1 beta biosynthetic process GO:0050725
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.
1 Q86SR2 (/ISS)
Positive regulation of fractalkine biosynthetic process GO:0050754
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.
1 Q86SR2 (/ISS)
Positive regulation of phagocytosis GO:0050766
Any process that activates or increases the frequency, rate or extent of phagocytosis.
1 Q86SR2 (/ISS)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 Q86SR2 (/IDA)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q86SR2 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 Q86SR2 (/IDA)
Azurophil granule GO:0042582
Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
1 Q86SR2 (/ISS)
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