The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 50: Periplasmic serine endoprotease DegP-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
194 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(184 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
194 P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI)
(184 more)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
194 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(184 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
194 P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI) P0C0V0 (/IPI)
(184 more)
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
158 O85291 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(148 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
156 P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(146 more)
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
92 P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP)
(82 more)
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
92 P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP)
(82 more)
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
92 P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM) P0C0V0 (/ISM)
(82 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
92 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(82 more)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
6 Q9KUF5 (/ISS) Q9KUF5 (/ISS) Q9KUF5 (/ISS) Q9KUF5 (/ISS) Q9KUF5 (/ISS) Q9KUF5 (/ISS)
Serine-type peptidase activity GO:0008236
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
1 Q8EAG0 (/ISS)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
163 P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(153 more)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
156 P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(146 more)
Protein quality control for misfolded or incompletely synthesized proteins GO:0006515
The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
156 P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(146 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
156 P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(146 more)
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
156 P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(146 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
102 P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA)
(92 more)
Proteolysis involved in cellular protein catabolic process GO:0051603
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
102 P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA)
(92 more)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
92 P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP)
(82 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
92 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(82 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
92 P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP)
(82 more)
Protein quality control for misfolded or incompletely synthesized proteins GO:0006515
The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
92 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(82 more)
Protein quality control for misfolded or incompletely synthesized proteins GO:0006515
The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
92 P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP)
(82 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
92 P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP)
(82 more)
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
92 P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP) P0C0V0 (/IEP)
(82 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
92 P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP) P0C0V0 (/IMP)
(82 more)
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
92 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(82 more)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
158 O85291 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS) P0C0V1 (/ISS)
(148 more)
Periplasmic space GO:0042597
The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
102 P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA) P39099 (/IDA)
(92 more)
Integral component of external side of plasma membrane GO:0071575
The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane.
102 P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA) P39099 (/ISA)
(92 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
92 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(82 more)
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
92 P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA) P0C0V0 (/IDA)
(82 more)