The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 39: Lin-7 homolog B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
78 Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI) Q9HAP6 (/IPI)
(68 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
68 O88951 (/IPI) O88951 (/IPI) O88952 (/IPI) O88952 (/IPI) O88952 (/IPI) O88952 (/IPI) O88952 (/IPI) O88952 (/IPI) O88952 (/IPI) O88952 (/IPI)
(58 more)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
57 O88951 (/ISO) O88951 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(47 more)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
57 O88951 (/ISO) O88951 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(47 more)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
56 Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI) Q792I0 (/IPI)
(46 more)
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
55 Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI) Q9NUP9 (/IPI)
(45 more)
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
55 O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(45 more)
L27 domain binding GO:0097016
Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.
55 Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA)
(45 more)
L27 domain binding GO:0097016
Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.
55 O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(45 more)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2 A5PEX5 (/IDA) Q9U245 (/IDA)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
2 A5PEX5 (/IPI) Q9U245 (/IPI)
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
2 A5PEX5 (/IPI) Q9U245 (/IPI)
L27 domain binding GO:0097016
Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.
2 A0A2R8QIA2 (/IPI) Q66IB0 (/IPI)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 Q9Z252 (/IDA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
78 Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS)
(68 more)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
57 O88951 (/IGI) O88951 (/IGI) O88952 (/IGI) O88952 (/IGI) O88952 (/IGI) O88952 (/IGI) O88952 (/IGI) O88952 (/IGI) O88952 (/IGI) O88952 (/IGI)
(47 more)
Morphogenesis of an epithelial sheet GO:0002011
The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.
55 Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP) Q9NUP9 (/IMP)
(45 more)
Morphogenesis of an epithelial sheet GO:0002011
The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.
55 O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(45 more)
Epidermal growth factor receptor signaling pathway GO:0007173
A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
2 A5PEX5 (/IMP) Q9U245 (/IMP)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
2 A5PEX5 (/IMP) Q9U245 (/IMP)
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
2 A5PEX5 (/IMP) Q9U245 (/IMP)
Positive regulation of vulval development GO:0040026
Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
2 A5PEX5 (/IMP) Q9U245 (/IMP)
Maintenance of epithelial cell apical/basal polarity GO:0045199
The maintenance of the apicobasal polarity of an epithelial cell.
2 A0A2R8QIA2 (/IMP) Q66IB0 (/IMP)
Protein localization to basolateral plasma membrane GO:1903361
Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane.
2 A5PEX5 (/IMP) Q9U245 (/IMP)
Cell-cell junction assembly GO:0007043
The aggregation, arrangement and bonding together of a set of components to form a junction between cells.
1 Q9Z252 (/NAS)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
1 Q8IMT8 (/NAS)
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
1 Q8IMT8 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
1 Q8IMT8 (/IMP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
113 A5PEX5 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA)
(103 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
111 O88952 (/IDA) O88952 (/IDA) O88952 (/IDA) O88952 (/IDA) O88952 (/IDA) O88952 (/IDA) O88952 (/IDA) O88952 (/IDA) O88952 (/IDA) O88952 (/IDA)
(101 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
79 Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS) Q9HAP6 (/TAS)
(69 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
57 O88951 (/IDA) O88951 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA)
(47 more)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
57 O88951 (/ISO) O88951 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(47 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
57 O88951 (/ISO) O88951 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(47 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
55 Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA)
(45 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
55 O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(45 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
55 O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(45 more)
MPP7-DLG1-LIN7 complex GO:0097025
A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.
55 Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA) Q9NUP9 (/IDA)
(45 more)
MPP7-DLG1-LIN7 complex GO:0097025
A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.
55 O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(45 more)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
55 Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA) Q792I0 (/IDA)
(45 more)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
55 O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO) O88952 (/ISO)
(45 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8IMT8 (/HDA)
Subapical complex GO:0035003
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
1 Q8IMT8 (/IDA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
1 Q8IMT8 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...