The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 29: tight junction protein ZO-1 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | A0A0G2K2P5 (/IPI) A0A2L2BH75 (/IPI) A0A2R8Q396 (/IPI) A0A2R8QMK9 (/IPI) E7F2W2 (/IPI) E9QET4 (/IPI) F1M4A0 (/IPI) O97758 (/IPI) P39447 (/IPI) Q07157 (/IPI) |
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
|
2 | A0A0B4K6Y7 (/IPI) Q9VHK3 (/IPI) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | A0A0G2K2P5 (/IPI) |
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | P39447 (/ISO) |
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | P39447 (/IPI) |
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
1 | Q07157 (/HDA) |
Connexin binding GO:0071253
Interacting selectively and non-covalently with a connexin, any of a group of related proteins that assemble to form gap junctions.
|
1 | P39447 (/IPI) |
Showing 1 to 7 of 7 entries
There are 41 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Pigmentation GO:0043473
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
|
5 | A0A2L2BH75 (/IGI) A0A2R8Q396 (/IGI) A0A2R8QMK9 (/IGI) E7F2W2 (/IGI) E9QET4 (/IGI) |
Pigmentation GO:0043473
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
|
5 | A0A2L2BH75 (/IMP) A0A2R8Q396 (/IMP) A0A2R8QMK9 (/IMP) E7F2W2 (/IMP) E9QET4 (/IMP) |
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
4 | H1UBK8 (/IMP) H1UBK9 (/IMP) Q56VX4 (/IMP) Q8I103 (/IMP) |
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
4 | H1UBK8 (/IGI) H1UBK9 (/IGI) Q56VX4 (/IGI) Q8I103 (/IGI) |
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
|
4 | H1UBK8 (/IMP) H1UBK9 (/IMP) Q56VX4 (/IMP) Q8I103 (/IMP) |
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
2 | A0A0B4K6Y7 (/IMP) Q9VHK3 (/IMP) |
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
|
2 | A0A0B4K6Y7 (/IMP) Q9VHK3 (/IMP) |
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
|
2 | E7FE08 (/IMP) X1WHN9 (/IMP) |
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
|
2 | A0A0B4K6Y7 (/IMP) Q9VHK3 (/IMP) |
Head involution GO:0008258
Movement of the anterior ectoderm to the interior of the embryo.
|
2 | A0A0B4K6Y7 (/IMP) Q9VHK3 (/IMP) |
Showing 1 to 10 of 41 entries
There are 40 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Bicellular tight junction GO:0005923
An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
|
13 |
A0A0G2K2P5 (/IDA)
A0A2L2BH75 (/IDA)
A0A2R8Q396 (/IDA)
A0A2R8QMK9 (/IDA)
E7F2W2 (/IDA)
E9QET4 (/IDA)
H1UBK8 (/IDA)
H1UBK9 (/IDA)
O97758 (/IDA)
P39447 (/IDA)
(3 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | A0A087X0K9 (/IDA) A0A0B4K6Y7 (/IDA) G3V1L9 (/IDA) G5E9E7 (/IDA) P39447 (/IDA) Q07157 (/IDA) Q9VHK3 (/IDA) |
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
|
7 | A0A0B4K6Y7 (/IDA) H1UBK8 (/IDA) H1UBK9 (/IDA) P39447 (/IDA) Q56VX4 (/IDA) Q8I103 (/IDA) Q9VHK3 (/IDA) |
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
|
5 | A0A087X0K9 (/IDA) G3V1L9 (/IDA) G5E9E7 (/IDA) P39447 (/IDA) Q07157 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | A0A087X0K9 (/IDA) G3V1L9 (/IDA) G5E9E7 (/IDA) Q07157 (/IDA) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
4 | A0A0B4K6Y7 (/IDA) P39447 (/IDA) Q07157 (/IDA) Q9VHK3 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | A0A0G2K2P5 (/IDA) P39447 (/IDA) Q07157 (/IDA) |
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
|
3 | A0A0B4K6Y7 (/IDA) P39447 (/IDA) Q9VHK3 (/IDA) |
Gap junction GO:0005921
A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.
|
3 | O97758 (/ISS) P39447 (/ISS) Q07157 (/ISS) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
3 | A0A0B4K6Y7 (/IDA) Q07157 (/IDA) Q9VHK3 (/IDA) |
Showing 1 to 10 of 40 entries