The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 944: Phospholipase D B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phospholipase D activity GO:0004630
Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.
1 Q54WR4 (/IMP)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phospholipid metabolic process GO:0006644
The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
1 Q54WR4 (/ISS)
Regulation of G protein-coupled receptor signaling pathway GO:0008277
Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.
1 Q54WR4 (/IMP)
Quorum sensing GO:0009372
The process in which single-celled organisms monitor their population density by detecting the concentration of small, diffusible signal molecules produced by the cells themselves.
1 Q54WR4 (/IMP)
Gene expression GO:0010467
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q54WR4 (/IDA)
Chemotaxis to cAMP GO:0043327
The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
1 Q54WR4 (/IMP)
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
1 Q54WR4 (/IMP)
Sorocarp sorus development GO:0048837
The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp.
1 Q54WR4 (/IMP)
Cell motility GO:0048870
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
1 Q54WR4 (/IGI)
Cell motility GO:0048870
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
1 Q54WR4 (/IMP)
Regulation of aggregation involved in sorocarp development GO:0060176
Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
1 Q54WR4 (/IMP)
Positive regulation of sorocarp spore cell differentiation GO:1901263
Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.
1 Q54WR4 (/IMP)
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
1 Q54WR4 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 Q54WR4 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 Q54WR4 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q54WR4 (/ISS)
Pseudopodium GO:0031143
A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.
1 Q54WR4 (/IDA)
Filamentous actin GO:0031941
A two-stranded helical polymer of the protein actin.
1 Q54WR4 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
1 Q54WR4 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q54WR4 (/IDA)