The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 67: Putative DCC-interacting protein 13-beta isoform 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 20 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 A0A2R8QM99 (/IPI) B2XCL9 (/IPI) B2XCM0 (/IPI) D3ZWA8 (/IPI) F1QA18 (/IPI) F1RB27 (/IPI) Q8K3G9 (/IPI) Q8K3G9 (/IPI) Q8K3H0 (/IPI) Q8NEU8 (/IPI)
(2 more)
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
3 Q8NEU8 (/IPI) Q9UKG1 (/IPI) Q9UKG1 (/IPI)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
2 Q8K3G9 (/ISO) Q8K3G9 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q9UKG1 (/IPI) Q9UKG1 (/IPI)
Protein kinase B binding GO:0043422
Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.
2 Q9UKG1 (/IPI) Q9UKG1 (/IPI)
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
2 Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8K3H0 (/ISO)
Protein kinase B binding GO:0043422
Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.
1 Q8K3H0 (/ISO)
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
1 Q8K3H0 (/ISO)
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
1 Q8K3H0 (/ISS)

There are 72 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adiponectin-activated signaling pathway GO:0033211
A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
4 Q8K3G9 (/IMP) Q8K3G9 (/IMP) Q9UKG1 (/IMP) Q9UKG1 (/IMP)
Negative regulation of glucose import GO:0046325
Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
4 B4F779 (/ISS) Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8NEU8 (/ISS)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
3 Q8NEU8 (/TAS) Q9UKG1 (/TAS) Q9UKG1 (/TAS)
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 Q8NEU8 (/IMP) Q9UKG1 (/IMP) Q9UKG1 (/IMP)
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Regulation of fibroblast migration GO:0010762
Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
3 Q8K3G9 (/IMP) Q8K3G9 (/IMP) Q8K3H0 (/IMP)
Regulation of fibroblast migration GO:0010762
Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Regulation of toll-like receptor 4 signaling pathway GO:0034143
Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
3 Q8K3G9 (/IMP) Q8K3G9 (/IMP) Q8K3H0 (/IMP)
Regulation of toll-like receptor 4 signaling pathway GO:0034143
Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Cellular response to hepatocyte growth factor stimulus GO:0035729
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
3 Q8K3G9 (/IMP) Q8K3G9 (/IMP) Q8K3H0 (/IMP)
Cellular response to hepatocyte growth factor stimulus GO:0035729
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
3 B4F779 (/ISS) Q8K3G9 (/ISS) Q8K3G9 (/ISS)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
3 Q8K3G9 (/IMP) Q8K3G9 (/IMP) Q8K3H0 (/IMP)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Negative regulation of glucose import GO:0046325
Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
3 Q8K3G9 (/IMP) Q8K3G9 (/IMP) Q8NEU8 (/IMP)
Positive regulation of macropinocytosis GO:1905303
Any process that activates or increases the frequency, rate or extent of macropinocytosis.
3 Q8K3G9 (/IMP) Q8K3G9 (/IMP) Q8K3H0 (/IMP)
Positive regulation of macropinocytosis GO:1905303
Any process that activates or increases the frequency, rate or extent of macropinocytosis.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Diet induced thermogenesis GO:0002024
The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
2 Q9UKG1 (/IMP) Q9UKG1 (/IMP)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
2 Q9UKG1 (/TAS) Q9UKG1 (/TAS)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Forebrain development GO:0030900
The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
2 A0A2R8QM99 (/IGI) F1QA18 (/IGI)
Adiponectin-activated signaling pathway GO:0033211
A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 Q8K3H0 (/ISS) Q8NEU8 (/ISS)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
2 Q8K3G9 (/ISO) Q8K3G9 (/ISO)
Negative regulation of fatty acid oxidation GO:0046322
Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Regulation of glucose import GO:0046324
Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
2 Q9UKG1 (/IMP) Q9UKG1 (/IMP)
Negative regulation of glucose import GO:0046325
Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
2 Q8K3G9 (/ISO) Q8K3G9 (/ISO)
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
2 Q9UKG1 (/IMP) Q9UKG1 (/IMP)
Positive regulation of melanin biosynthetic process GO:0048023
Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
2 Q9UKG1 (/IMP) Q9UKG1 (/IMP)
Negative regulation of neurogenesis GO:0050768
Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
2 Q8K3G9 (/ISO) Q8K3G9 (/ISO)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
2 Q8K3G9 (/ISS) Q8K3G9 (/ISS)
Positive regulation of phagocytosis, engulfment GO:0060100
Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Extrinsic apoptotic signaling pathway in absence of ligand GO:0097192
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
2 Q9UKG1 (/TAS) Q9UKG1 (/TAS)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Negative regulation of cytokine production involved in inflammatory response GO:1900016
Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Positive regulation of cytokine production involved in inflammatory response GO:1900017
Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
2 Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Negative regulation of cellular response to insulin stimulus GO:1900077
Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Regulation of protein localization to plasma membrane GO:1903076
Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.
2 Q9UKG1 (/IMP) Q9UKG1 (/IMP)
Negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis GO:1905450
Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
2 Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis GO:1905451
Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Negative regulation of neural precursor cell proliferation GO:2000178
Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.
2 Q8K3G9 (/IMP) Q8K3G9 (/IMP)
Diet induced thermogenesis GO:0002024
The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system.
1 Q8NEU8 (/ISS)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
1 Q8K3H0 (/ISO)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
1 Q8K3H0 (/ISS)
Cold acclimation GO:0009631
Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
1 Q8NEU8 (/ISS)
Adiponectin-activated signaling pathway GO:0033211
A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q8K3H0 (/ISO)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 Q8NEU8 (/IMP)
Negative regulation of fatty acid oxidation GO:0046322
Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.
1 Q8NEU8 (/ISS)
Regulation of glucose import GO:0046324
Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
1 Q8K3H0 (/ISO)
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
1 Q8K3H0 (/ISO)
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
1 Q8K3H0 (/ISS)
Positive regulation of melanin biosynthetic process GO:0048023
Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
1 Q8K3H0 (/ISO)
Positive regulation of melanin biosynthetic process GO:0048023
Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
1 Q8K3H0 (/ISS)
Negative regulation of neurogenesis GO:0050768
Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
1 Q8NEU8 (/ISS)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 Q8NEU8 (/IDA)
Positive regulation of phagocytosis, engulfment GO:0060100
Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
1 Q8NEU8 (/ISS)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
1 Q8NEU8 (/ISS)
Negative regulation of cytokine production involved in inflammatory response GO:1900016
Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
1 Q8NEU8 (/ISS)
Positive regulation of cytokine production involved in inflammatory response GO:1900017
Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
1 Q8K3H0 (/IMP)
Negative regulation of cellular response to insulin stimulus GO:1900077
Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.
1 Q8NEU8 (/ISS)
Regulation of protein localization to plasma membrane GO:1903076
Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.
1 Q8K3H0 (/ISO)
Negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis GO:1905450
Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
1 Q8K3H0 (/IMP)
Positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis GO:1905451
Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
1 Q8NEU8 (/ISS)
Negative regulation of neural precursor cell proliferation GO:2000178
Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.
1 Q8NEU8 (/ISS)

There are 44 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
6 A0A2R8QM99 (/IDA) B2XCL9 (/IDA) F1QA18 (/IDA) Q8K3H0 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
5 A0A2R8QM99 (/IGI) B2XCL9 (/IGI) B2XCM0 (/IGI) F1QA18 (/IGI) F1RB27 (/IGI)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 Q8K3G9 (/IDA) Q8K3G9 (/IDA) Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q8K3G9 (/IDA) Q8K3G9 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
4 Q8K3H0 (/IDA) Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
3 Q8K3G9 (/IDA) Q8K3G9 (/IDA) Q8K3H0 (/IDA)
Ruffle GO:0001726
Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 Q8K3G9 (/ISS) Q8K3G9 (/ISS) Q8K3H0 (/ISS)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
3 Q8NEU8 (/IDA) Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
3 Q8K3G9 (/ISO) Q8K3G9 (/ISO) Q8K3H0 (/ISO)
Early phagosome GO:0032009
A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.
3 Q8K3G9 (/IDA) Q8K3G9 (/IDA) Q8K3H0 (/IDA)
Early phagosome GO:0032009
A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Macropinosome GO:0044354
A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.
3 Q8K3G9 (/IDA) Q8K3G9 (/IDA) Q8K3H0 (/IDA)
Macropinosome GO:0044354
A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.
3 Q8NEU8 (/ISS) Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
3 Q8NEU8 (/HDA) Q9UKG1 (/HDA) Q9UKG1 (/HDA)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
2 Q9UKG1 (/ISS) Q9UKG1 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
2 Q9UKG1 (/TAS) Q9UKG1 (/TAS)
Vesicle membrane GO:0012506
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
2 Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
2 Q8K3G9 (/ISS) Q8K3G9 (/ISS)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
2 Q8K3G9 (/ISO) Q8K3G9 (/ISO)
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
2 Q8K3G9 (/IDA) Q8K3G9 (/IDA)
Early phagosome membrane GO:0036186
The lipid bilayer surrounding an early phagosome.
2 Q8K3G9 (/IDA) Q8K3G9 (/IDA)
Intracellular vesicle GO:0097708
Any vesicle that is part of the intracellular region.
2 Q9UKG1 (/IDA) Q9UKG1 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 A5PKI0 (/IDA)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 Q8K3H0 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8K3H0 (/ISO)
Vesicle membrane GO:0012506
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
1 Q8K3H0 (/ISO)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
1 Q8NEU8 (/IDA)
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
1 Q8NEU8 (/ISS)
Early phagosome membrane GO:0036186
The lipid bilayer surrounding an early phagosome.
1 Q8NEU8 (/ISS)
Intracellular vesicle GO:0097708
Any vesicle that is part of the intracellular region.
1 Q8K3H0 (/ISO)
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