The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 437: Focal adhesion kinase, isoform F

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoskeletal anchoring at plasma membrane GO:0007016
A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.
7 B7YZL9 (/ISS) E1JGM8 (/ISS) Q0E917 (/ISS) Q5BIG9 (/ISS) Q9U472 (/ISS) Q9U531 (/ISS) Q9U5Y2 (/ISS)
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
7 B7YZL9 (/IMP) E1JGM8 (/IMP) Q0E917 (/IMP) Q5BIG9 (/IMP) Q9U472 (/IMP) Q9U531 (/IMP) Q9U5Y2 (/IMP)
Negative regulation of receptor recycling GO:0001920
Any process that stops, prevents, or reduces the rate of receptor recycling.
1 B7YZL9 (/IGI)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
7 B7YZL9 (/IDA) E1JGM8 (/IDA) Q0E917 (/IDA) Q5BIG9 (/IDA) Q9U472 (/IDA) Q9U531 (/IDA) Q9U5Y2 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
7 B7YZL9 (/ISS) E1JGM8 (/ISS) Q0E917 (/ISS) Q5BIG9 (/ISS) Q9U472 (/ISS) Q9U531 (/ISS) Q9U5Y2 (/ISS)
Type Ib terminal bouton GO:0061176
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.
7 B7YZL9 (/IDA) E1JGM8 (/IDA) Q0E917 (/IDA) Q5BIG9 (/IDA) Q9U472 (/IDA) Q9U531 (/IDA) Q9U5Y2 (/IDA)
Type Is terminal bouton GO:0061177
Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.
7 B7YZL9 (/IDA) E1JGM8 (/IDA) Q0E917 (/IDA) Q5BIG9 (/IDA) Q9U472 (/IDA) Q9U531 (/IDA) Q9U5Y2 (/IDA)