CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 43: FERM domain-containing protein 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
4 | Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q7Z6J6 (/IPI) Q7Z6J6 (/IPI) Q7Z6J6 (/IPI) Q7Z6J6 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
4 | Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) |
|
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
1 | Q6P5H6 (/ISO) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q6P5H6 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
4 | Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) |
|
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
|
4 | Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) |
|
Negative regulation of cell motility GO:2000146
Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
|
4 | Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) Q7Z6J6 (/IMP) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
1 | Q6P5H6 (/ISO) |
|
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
|
1 | Q6P5H6 (/ISO) |
|
Negative regulation of cell motility GO:2000146
Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
|
1 | Q6P5H6 (/ISO) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
|
4 | Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) Q7Z6J6 (/IDA) |
|
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
|
1 | Q6P5H6 (/ISO) |