CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 394: Uncharacterized protein, isoform B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
6 | A0A0B4KG76 (/ISS) A0A0B4KGK7 (/ISS) E1JJ52 (/ISS) Q8IPP5 (/ISS) Q9TY11 (/ISS) Q9VNG9 (/ISS) |
Integrin binding GO:0005178
Interacting selectively and non-covalently with an integrin.
|
6 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
6 | A0A0B4KG76 (/IPI) A0A0B4KGK7 (/IPI) E1JJ52 (/IPI) Q8IPP5 (/IPI) Q9TY11 (/IPI) Q9VNG9 (/IPI) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cell adhesion mediated by integrin GO:0033627
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
|
6 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
|
6 | A0A0B4KG76 (/ISS) A0A0B4KGK7 (/ISS) E1JJ52 (/ISS) Q8IPP5 (/ISS) Q9TY11 (/ISS) Q9VNG9 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
6 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
6 | A0A0B4KG76 (/IDA) A0A0B4KGK7 (/IDA) E1JJ52 (/IDA) Q8IPP5 (/IDA) Q9TY11 (/IDA) Q9VNG9 (/IDA) |