The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 376: Exocyst complex component 8

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Meiotic spindle organization GO:0000212
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Actomyosin contractile ring contraction GO:0000916
The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Meiosis I cytokinesis GO:0007110
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Meiosis II cytokinesis GO:0007111
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
3 Q7KRZ3 (/NAS) Q8SWU0 (/NAS) Q9VBI4 (/NAS)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Synaptic vesicle targeting GO:0016080
The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
3 Q7KRZ3 (/NAS) Q8SWU0 (/NAS) Q9VBI4 (/NAS)
Synaptic vesicle docking GO:0016081
The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
3 Q7KRZ3 (/NAS) Q8SWU0 (/NAS) Q9VBI4 (/NAS)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
3 Q7KRZ3 (/ISS) Q8SWU0 (/ISS) Q9VBI4 (/ISS)
Endocytic recycling GO:0032456
The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Maintenance of epithelial cell apical/basal polarity GO:0045199
The maintenance of the apicobasal polarity of an epithelial cell.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
3 Q7KRZ3 (/IMP) Q8SWU0 (/IMP) Q9VBI4 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Exocyst GO:0000145
A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.
3 Q7KRZ3 (/IDA) Q8SWU0 (/IDA) Q9VBI4 (/IDA)
Exocyst GO:0000145
A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.
3 Q7KRZ3 (/ISS) Q8SWU0 (/ISS) Q9VBI4 (/ISS)
Exocyst GO:0000145
A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.
3 Q7KRZ3 (/NAS) Q8SWU0 (/NAS) Q9VBI4 (/NAS)