The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 288: Leucine-rich repeat, isoform C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
4 A0A0B4KEE7 (/IEP) A1Z734 (/IEP) E1JGZ7 (/IEP) E1JGZ8 (/IEP)
Response to insecticide GO:0017085
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
4 A0A0B4KEE7 (/IEP) A1Z734 (/IEP) E1JGZ7 (/IEP) E1JGZ8 (/IEP)
Negative regulation of immune response GO:0050777
Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
4 A0A0B4KEE7 (/IMP) A1Z734 (/IMP) E1JGZ7 (/IMP) E1JGZ8 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
4 A0A0B4KEE7 (/ISM) A1Z734 (/ISM) E1JGZ7 (/ISM) E1JGZ8 (/ISM)
Negative regulation of NIK/NF-kappaB signaling GO:1901223
Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
4 A0A0B4KEE7 (/IMP) A1Z734 (/IMP) E1JGZ7 (/IMP) E1JGZ8 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Muscle tendon junction GO:0005927
A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.
4 A0A0B4KEE7 (/IDA) A1Z734 (/IDA) E1JGZ7 (/IDA) E1JGZ8 (/IDA)