CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 281: Actin associated protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | O36027 (/IPI) Q12446 (/IPI) Q12446 (/IPI) |
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
2 | Q12446 (/IDA) Q12446 (/IDA) |
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
2 | Q12446 (/IPI) Q12446 (/IPI) |
|
Arp2/3 complex binding GO:0071933
Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).
|
1 | O36027 (/IDA) |
Showing 1 to 4 of 4 entries
There are 26 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of Arp2/3 complex-mediated actin nucleation GO:2000601
Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.
|
3 | O36027 (/IDA) Q12446 (/IDA) Q12446 (/IDA) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
2 | A0A1D8PU03 (/IMP) O36027 (/IMP) |
|
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
|
2 | Q12446 (/IDA) Q12446 (/IDA) |
|
Positive regulation of actin filament bundle assembly GO:0032233
Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.
|
2 | Q12446 (/IDA) Q12446 (/IDA) |
|
Actin nucleation GO:0045010
The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
|
2 | Q12446 (/IDA) Q12446 (/IDA) |
|
Actin cortical patch localization GO:0051666
Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
|
2 | Q12446 (/IGI) Q12446 (/IGI) |
|
Actin cortical patch localization GO:0051666
Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
|
2 | Q12446 (/IMP) Q12446 (/IMP) |
|
Ribosomal small subunit assembly GO:0000028
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
|
1 | A0A1D8PU03 (/IMP) |
|
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
|
1 | O36027 (/IGI) |
|
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
|
1 | O36027 (/IMP) |
Showing 1 to 10 of 26 entries
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
|
4 | A0A1D8PU03 (/IDA) O36027 (/IDA) Q12446 (/IDA) Q12446 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q12446 (/HDA) Q12446 (/HDA) |
|
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
|
2 | Q12446 (/HDA) Q12446 (/HDA) |
|
Hyphal tip GO:0001411
The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
|
1 | A0A1D8PU03 (/IDA) |
|
Cellular bud GO:0005933
A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.
|
1 | A0A1D8PU03 (/IDA) |
|
Medial cortex GO:0031097
A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
|
1 | O36027 (/IDA) |
|
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
|
1 | O36027 (/IDA) |
Showing 1 to 7 of 7 entries
