CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 247: pleckstrin homology domain-containing family F mem...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q96S99 (/IPI) |
|
Phosphatidylinositol-5-phosphate binding GO:0010314
Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.
|
1 | Q96S99 (/IDA) |
|
Phosphatidylinositol-5-phosphate binding GO:0010314
Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.
|
1 | Q3TB82 (/ISO) |
|
Phosphatidylinositol-3-phosphate binding GO:0032266
Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.
|
1 | Q96S99 (/IDA) |
|
Phosphatidylinositol-3-phosphate binding GO:0032266
Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.
|
1 | Q3TB82 (/ISO) |
|
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
1 | Q96S99 (/IDA) |
|
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
1 | Q3TB82 (/ISO) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
|
1 | Q96S99 (/IMP) |
|
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
|
1 | Q3TB82 (/ISO) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q96S99 (/IDA) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q3TB82 (/ISO) |
|
Vesicle organization GO:0016050
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
|
1 | Q96S99 (/IMP) |
|
Vesicle organization GO:0016050
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
|
1 | Q3TB82 (/ISO) |
|
Regulation of mitochondrial membrane permeability GO:0046902
Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
|
1 | Q3TB82 (/ISO) |
|
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
1 | Q96S99 (/IMP) |
|
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
1 | Q3TB82 (/ISO) |
|
Positive regulation of intrinsic apoptotic signaling pathway GO:2001244
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
1 | Q3TB82 (/IDA) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
2 | Q3TB82 (/IDA) Q96S99 (/IDA) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
1 | Q3TB82 (/ISO) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q96S99 (/IC) |
|
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
1 | Q96S99 (/IC) |
