CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 240: Myotubularin-related protein 9
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q96QG7 (/IPI) Q96QG7 (/IPI) Q96QG7 (/IPI) Q9Z2D0 (/IPI) |
|
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
|
3 | Q96QG7 (/IPI) Q96QG7 (/IPI) Q96QG7 (/IPI) |
|
Phosphatidylinositol-3-phosphatase activity GO:0004438
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.
|
1 | Q8SZY7 (/ISS) |
|
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
|
1 | Q9Z2D0 (/ISO) |
|
Enzyme regulator activity GO:0030234
Binds to and modulates the activity of an enzyme.
|
1 | Q9Z2D0 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphatidylinositol biosynthetic process GO:0006661
The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
|
3 | Q96QG7 (/TAS) Q96QG7 (/TAS) Q96QG7 (/TAS) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
3 | Q96QG7 (/IPI) Q96QG7 (/IPI) Q96QG7 (/IPI) |
|
Positive regulation of phosphatase activity GO:0010922
Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
3 | Q96QG7 (/IDA) Q96QG7 (/IDA) Q96QG7 (/IDA) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
3 | Q96QG7 (/IDA) Q96QG7 (/IDA) Q96QG7 (/IDA) |
|
Regulation of phosphatidylinositol dephosphorylation GO:0060304
Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.
|
3 | Q96QG7 (/IDA) Q96QG7 (/IDA) Q96QG7 (/IDA) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q9Z2D0 (/ISO) |
|
Positive regulation of phosphatase activity GO:0010922
Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
1 | Q9Z2D0 (/ISO) |
|
Phosphatidylinositol dephosphorylation GO:0046856
The process of removing one or more phosphate groups from a phosphatidylinositol.
|
1 | Q8SZY7 (/ISS) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
1 | Q9Z2D0 (/ISO) |
|
Regulation of phosphatidylinositol dephosphorylation GO:0060304
Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.
|
1 | Q9Z2D0 (/ISO) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | Q96QG7 (/TAS) Q96QG7 (/TAS) Q96QG7 (/TAS) Q9Z2D0 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q96QG7 (/IDA) Q96QG7 (/IDA) Q96QG7 (/IDA) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
3 | Q96QG7 (/IDA) Q96QG7 (/IDA) Q96QG7 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9Z2D0 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8SZY7 (/ISS) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q9Z2D0 (/ISO) |
