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CATH Superfamily 2.30.29.30

Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1IQ motif and SEC7 domain-containing protein 1Kalirin RhoGEF kinase bpleckstrin homology domain-containing family A member 1 isoform X1Intersectin 1Rho guanine nucleotide exchange factor 1Guanine nucleotide exchange factor DBSG protein-coupled receptor kinaseRho guanine nucleotide exchange factor 7Insulin receptor substrate 1pleckstrin homology domain-containing family M member 2Rho guanine nucleotide exchange factor (GEF) 25Pleckstrin 2SC:10Homer homolog 1 (Drosophila)Rho guanine nucleotide exchange factor 9E3 SUMO-protein ligase RanBP2T cell lymphoma invasion and metastasis 1Enah/Vasp-like, isoform CRA_aRan-specific GTPase-activating protein 1Ran-specific GTPase-activating proteinSC:11Calcium-dependent secretion activator 2 isoform BArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2Engulfment and cell motility protein 1Phosphoinositide phospholipase CDocking protein 3FACT complex subunit POB3protein Dok-7 isoform X2dynamin-3 isoform X1FACT complex subunit POB3dynamin-1-like isoform X1target of rapamycin complex 2 subunit MAPKAP1 isoform X3SC:12Disabled homolog 2 isoform 1SHC-transforming protein 1 isoform 3Low density lipoprotein receptor adapter protein 1amyloid beta A4 precursor protein-binding family B member 3 isoform X1DCC-interacting protein 13-alpha isoform X2SC:13Tyrosine-protein kinaseSC:14Adaptin ear-binding coat-associated protein 1Signal transducing adaptor family member 1SC:2Rho GTPase activating protein 21Pleckstrin homology domain-containing family A member 4General transcription factor IIH subunit 1ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X1unconventional myosin-XRho GTPase activating protein 9Putative src kinase-associated phosphoprotein 2PleckstrinTranscription initiation factor TFIIH subunitSC:3amyloid beta A4 precursor protein-binding family B member 2Ankyrin repeat and sterile alpha motif domain-containing protein 1Banillin isoform X1cerebral cavernous malformations 2 protein-likeSH2B adapter protein 2Epidermal growth factor receptor kinase substrate 8-like protein 1Integrin beta-1-binding protein 1SC:4Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)Non-specific serine/threonine protein kinaseTensin 1rho GTPase-activating protein 22 isoform X13-phosphoinositide dependent protein kinase 1protein-tyrosine kinase 2-beta isoform X1methylosome subunit pICln isoform X1Vacuolar protein sorting 36 homologSC:5Serine/threonine-protein phosphatase 4 regulatory subunit 3BPleckstrin homology domain-containing family A member 8Putative mRNA-decapping enzyme 1AFYVE, RhoGEF and PH domain containing 6Coactivator-associated arginine methyltransferase 1mRNA-decapping enzyme 1BmRNA-decapping enzyme subunit 1SC:6Ras association (RalGDS/AF-6) and pleckstrin homology domains 1growth factor receptor-bound protein 10 isoform X1Growth factor receptor-bound protein 14SC:7Actin filament-associated protein 1-like 2 isoform 1Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2Oxysterol-binding proteinRho-associated protein kinase 2FERM, RhoGEF and pleckstrin domain-containing protein 1Sprouty-related, EVH1 domain containing 2Putative DCC-interacting protein 13-beta isoform 2SET binding factor 2collagen type IV alpha-3-binding protein-like isoform X2Oxysterol-binding proteinswitch-associated protein 70 isoform X2Nuclear pore complex protein Nup50Rho GTPase activating protein 27FYVE, RhoGEF and PH domain-containing protein 6PleckstrinDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositideUnconventional myosin-XTBC1 domain family member 2A isoform X1src kinase-associated phosphoprotein 1Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1Oxysterol-binding family proteinSC:8Insulin receptor substrate 1Neurofibromin 1unconventional myosin-VIIaarf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2Myotubularin related protein 6Sorting nexin-17 isoform1Rho guanine nucleotide exchange factor 3Exocyst complex component 8unconventional myosin-Xkrev interaction trapped protein 1 isoform X1Docking protein 1Docking protein 7sharpin isoform X1FYVE, RhoGEF and PH domain containing 3Target of rapamycin complex 2 subunit AVO1Ran-specific GTPase-activating protein 2Muscle M-line assembly protein unc-89SC:9FERM, RhoGEF and pleckstrin domain-containing protein 1T cell lymphoma invasion and metastasis 1Erythrocyte membrane protein band 4.1Band 4.1-like protein 5 isoform 1Radixin isoform 1Amyloid beta (A4) protein bPleckstrin homology like domain family B member 1GRAM domain containing 1BCytohesin 1dynamin-1 isoform X2Oxysterol-binding proteinPutative TBC1 domain family member 8Bdedicator of cytokinesis protein 9 isoform X1FACT complex subunit SPT16Rho guanine nucleotide exchange factor 2Putative FERM domain-containing protein 4AKinesin family member 1BSpectrin beta chainPhosphoinositide phospholipase CTalin 2protein numb isoform X1Non-specific serine/threonine protein kinaseFermitin family homolog 2Myotubularin 1, isoform CRA_aTBC1 domain family member 9 isoform X1pleckstrin homology domain-containing family A member 1 isoform X2FERM domain-containing protein 5amyloid beta A4 precursor protein-binding family A member 1vasodilator-stimulated phosphoprotein isoform X2Vav guanine nucleotide exchange factor 2PH and SEC7 domain-containing protein 3Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein-likeSerine/threonine-protein kinaseFermitin family homolog 2 (Drosophila)focal adhesion kinase 1 isoform X1neurobeachin isoform X1Diacylglycerol kinaseOxysterol binding protein 1Phosphoinositide phospholipase CFERM and PDZ domain-containing protein 4Son of sevenless homolog 1 (Drosophila)Pleckstrin homology domain-containing family B member 2Oxysterol-binding proteinTBC1 domain family member 4 isoform X1Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1unconventional myosin-VIIaArf-GAP with dual PH domain-containing protein 1Citron rho-interacting serine/threonine kinaseDocking protein 5Pleckstrin homology domain-containing family A member 5GRAM domain-containing protein 2B isoform 2Oxysterol-binding proteinRAS p21 protein activator 1kalirin isoform X1Connector enhancer of kinase suppressor of Ras 2WD repeat and FYVE domain containing 3IQ motif and SEC7 domain-containing protein 3Fact complex subunit ssrp1Arf-GAP with dual PH domain-containing protein 1Rho GTPase activating protein 12FYVE, RhoGEF and PH domain-containing protein 4Target of rapamycin complex 2 subunit MAPKAP1ran-binding protein 3 isoform X2Tyrosine-protein phosphatase non-receptor type 13C-Jun-amino-terminal kinase-interacting protein 1 isoform X2Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Docking protein 4active breakpoint cluster region-related protein isoform X2FYVE, RhoGEF and PH domain-containing protein 4PhospholipaseRho GTPase activating protein 26ras-specific guanine nucleotide-releasing factor 1 isoform X2GULP PTB domain containing engulfment adaptor 1FACT complex subunit SSRP1Actin filament associated protein 1carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-likePutative rab gtpase-activating protein 1Neuronal guanine nucleotide exchange factorneural Wiskott-Aldrich syndrome proteinKinesin-like calmodulin-binding protein (ZWICHEL)pleckstrin homology domain-containing family G member 2myosin phosphatase Rho-interacting protein isoform X1Putative FERM domain-containing protein 6Ran-specific GTPase-activating protein-likeVentricular zone-expressed PH domain-containing protein-like 1ADP-ribosylation factor GTPase-activating protein AGD3CDC42 binding protein kinase betaPleckstrin homology domain-containing family G member 5amyloid beta A4 precursor protein-binding family B member 3 isoform X2Ras GTPase-activating protein 2 isoform 3FACT complex subunit POB3SH3 domain-binding protein 2 isoform X2Tyrosine-protein phosphatase non-receptor typeAdaptin ear-binding coat-associated protein1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gammaPTB-containing, cubilin and LRP1-interacting proteinPutative rho GTPase-activating protein 10mRNA-decapping enzyme-like proteinDCC-interacting protein 13-beta isoform X2Rho GTPase activating protein 42protein ECT2 isoform X2Putative E3 ubiquitin-protein ligase MYLIPTBC1 domain family member 1 isoform X1GRB2-associated-binding protein 1 isoform X1Pleckstrin homology domain-containing family F member 21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gammaFibroblast growth factor receptor substrate 2Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1Actin filament-associated protein 1-like 2 isoform 1differentially expressed in FDCP 6 homologArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1epidermal growth factor receptor kinase substrate 8ras-specific guanine nucleotide-releasing factor 1 isoform X2Tyrosine-protein kinaseArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1Oligophrenin 1TBC1 domain family member 8BArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1Myotubularin related protein 12Actin filament associated protein 1-like 1myosin phosphatase Rho-interacting protein isoform X2Tyrosine-protein kinaseSH2B adapter protein 1 isoform X1arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3Unconventional myosin-Xobscurin isoform X5Myotubularin related protein 10Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3Rho guanine nucleotide exchange factor (GEF) 10-like aarf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3rab GTPase-activating protein 1-like isoform X1PH domain-containing proteinkinesin-like protein unc-104 isoform X6Rho guanine nucleotide exchange factor (GEF) 19Protein CBR-LIN-10, isoform aArf-GAP with GTPase, ANK repeat and PH domain-containing protein 2Dynamin-2AFACT complex subunit SSRP1Oxysterol-binding protein-related protein 1CFERM domain-containing protein 8Rho GTPase activating protein 20Epidermal growth factor receptor kinase substrate 8-like 2Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3Lysosomal trafficking regulatoramyloid beta A4 precursor protein-binding family A member 3arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2GRAM domain containing 4ran-binding protein 3-like isoform X2Polarized growth protein (Boi2)Oxysterol-binding proteinBardet-Biedl syndrome 5 isoform 1rhotekin isoform X3Pleckstrin homology (PH) domain-containing proteinpleckstrin homology domain-containing family O member 1Tyrosine-protein kinasearf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X2Myotubularin-related protein 9serine/threonine-protein kinase MRCK gamma isoform X1Pleckstrin 2Tyrosine-protein kinaseRan-binding protein 1 bpleckstrin homology domain-containing family F member 1Capping protein regulator and myosin 1 linker 2Sesquipedalian-1 isoform ASyntrophin beta 2ARF GTPase activator (Csx2)F-actin-uncapping protein LRRC16A isoform X1Ran-specific GTPase-activating protein 1niban-like protein 1 isoform X1Oxysterol-binding proteinPleckstrin homology domain-containing family M member 3SET binding factor 2TBC1 domain family member 8Rho GTPase activating protein 15Disabled, isoform FStress activated MAP kinase interacting proteinPotential exocyst complex component Exo84BAG-associated GRAM protein 1 isoform X2Capping protein, Arp2/3 and myosin-I linker protein 3PH and SEC7 domain-containing protein 4Rho guanine nucleotide exchange factor 17Synaptosomal-associated protein 47Pleckstrin homology-like domain family A member 3pleckstrin homology domain-containing family M member 3Rho guanine nucleotide exchange factor 15alsin isoform X3Rhotekin 2pleckstrin homology domain-containing family H member 3Oxysterol-binding proteinFYVE, RhoGEF and PH domain-containing protein 1Uncharacterized protein, isoform BActin associated proteinConnector enhancer of kinase suppressor of Ras 1 variantRas GTPase-activating protein 4 isoform 1pleckstrin homology domain-containing family H member 3 isoform X2regulator of G-protein signaling 3 isoform X1PH-protein kinase domain containing proteinTBC1 domain family member 4 isoform X1Leucine-rich repeat, isoform CEpidermal growth factor receptor kinase substrate 8SH2 domain-containing protein 5insulin receptor substrate 2sesquipedalian-2 isoform X2EPS8 like 3WAS/WASL-interacting protein family member 1pleckstrin homology domain-containing family H member 2 isoform X1Regulator of G protein signaling 12Sorting nexin 31FACT complex subunit SSRP1SH2B adapter protein 3 isoform X2pleckstrin homology domain-containing family J member 1Neurobeachin-like protein 2Rho GTPase-activating protein 7Sterol 3-beta-glucosyltransferaseBeta-1-syntrophin isoform 13-phosphoinositide-dependent protein kinase 1Uncharacterized protein, isoform ABeta-1-syntrophin isoform 1Rho-associated protein kinase 1Uncharacterized protein, isoform BGTP binding protein (Bud4)Ran binding protein 1Diacylglycerol kinaseBeta-1-syntrophin isoform 1pleckstrin homology domain-containing family M member 1 isoform X1Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2Amyloid beta A4 protein-binding family B memberinsulin receptor substrate 4Dynamin 1Diacylglycerol kinaseOxysterol-binding protein-related protein 1CUncharacterized protein, isoform BUncharacterized protein, isoform CPhosphoinositide-dependent kinase 1, isoform FPleckstrin homology domain-containing family N member 1TBC1 domain family member 2BRho guanyl nucleotide exchange factoralpha-1-syntrophinTBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X2Uncharacterized protein, isoform CUncharacterized protein, isoform CPleckstrin homology domain-containing family H member 2Protein still life, isoform SIF typeUncharacterized protein, isoform DRho guanine nucleotide exchange factor 39Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2beta-1-syntrophin isoform X1Calcium-dependent secretion activatorUncharacterized protein, isoform Cunconventional myosin-XV isoform X1Pleckstrin homology domain-containing family H member 2Docking protein 3Non-specific serine/threonine protein kinaseTranscription factor SipA3AGC family protein kinasePhospholipaseFACT complex subunit SSRP1Nuclear pore complex protein NUP50ALnk, isoform Dprotein SPIRRIG isoform X1Non-specific serine/threonine protein kinaseKinesin family proteinInner membrane complex sub-compartment protein 1 (ISP1)Protein ENHANCED DISEASE RESISTANCE 2-likeAlpha-1-syntrophinTBC1 domain family member 1 isoform BUncharacterized protein, isoform BPutative E3 ubiquitin-protein ligase HERC1Rho guanyl nucleotide exchange factorRelated to CDC24-GTP/GDP exchange factor for Cdc42pUncharacterized protein, isoform BNeutral sphingomyelinase activation associated factorUncharacterized protein, isoform BOxysterol binding proteinDynamin, putativePebble, isoform BUncharacterized protein, isoform BProtein still life, isoform SIF typeinsulin receptor substrate 1-likeRelated to Neural Wiskott-Aldrich syndrome proteinExocyst complex component 8Shc transforming proteinUncharacterized protein, isoform Adynamin-1 isoform X6Interferon-induced guanylate-binding protein 1-likeFERM domain-containing proteinUncharacterized protein, isoform AUncharacterized protein, isoform BUncharacterized protein, isoform Ainsulin receptor substrate 1-likeOxysterol-binding proteinSerine/threonine-protein kinase D2von Willebrand RING finger domain-containing proteinAGC/PDK1 protein kinase, variant 1Sterol 3-beta-glucosyltransferasecentaurin-gamma-1A isoform X2Uncharacterized protein, isoform BNon-specific serine/threonine protein kinasePhosphoinositide phospholipase CUncharacterized protein, isoform AUncharacterized protein, isoform Cdocking protein 1 isoform X1FYVE, RhoGEF and PH domain-containing protein 3Uncharacterized protein, isoform BUnplaced genomic scaffold supercont1.125, whole genome shotgun sequenceNon-specific serine/threonine protein kinaseRHO1 GDP-GTP exchange protein 2Putative RNA polymerase II transcription factor related proteinC2 domain-containing protein-likePleckstrin (PH) domain containing family proteinInsulin receptor substrate 2-BA-kinase anchor protein 13Blast:Rho GTPase-activating protein 26Phosphoinositide phospholipase Cvacuolar protein-sorting-associated protein 36 isoform X2Uncharacterized protein, isoform DCell 12A endoglucanaseCell 12A endoglucanaseTrio, isoform BPH domain proteinmRNA-decapping enzyme subunit 1CLNS1A isoform 4Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform BPhosphoinositide phospholipase CPhosphatidylinositol kinase (PIK-H1)Phospholipase DDHD1Ysp1pAdaptin ear-binding coat-associated protein 1GEM-like protein 5CLNS1A isoform 7Uncharacterized protein, isoform CUnplaced genomic scaffold supercont1.6, whole genome shotgun sequenceCalcium-dependent protein kinase 7Non-specific serine/threonine protein kinaseRho guanine nucleotide exchange factor 17Si:ch211-193c2.2CLNS1A isoform 4Focal adhesion kinase, isoform Funcharacterized protein LOC108093793 isoform X2Protein kinase CUncharacterized proteinInsulin receptor substrate 1Sprouty related EVH1 domain containing 3Decapping enzyme Dcp1, putativeephexin-1 isoform X2Protein kinase, putativeRanBP-type and C3HC4-type zinc finger-containing protein 1Syntrophin gamma 1Histone-arginine methyltransferase CARMEROxysterol-binding proteinPez, isoform ARho GTPase activator (Bem3)Uncharacterized protein, isoform DPsy2pType II inositol-3,4-bisphosphate 4-phosphataseInsulin receptor substrate 1Uncharacterized protein, isoform BArf-GAP with GTPase, ANK repeat and PH domain-containing protein 2Pleckstrin y domain-containing family H member 2Coactivator associated arginine methyltransferase 1TeNSin homologCCM2 like scaffold proteinCell 12A endoglucanaseAdaptin ear-binding coat-associated protein 2carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-likeBlown fuse, isoform BUncharacterized proteinunconventional myosin-XVPhosphatidylinositol 3-kinase 2Serine threonine protein phosphatase 2a 59 kDa regulatory subunit bPleckstrin y domain-containing family H member 2Mitogen-activated protein kinaseAGC/RSK/RSKP90 protein kinaseAGC/RSK/RSKP90 protein kinaseOxysterol-binding protein-related protein 2TBC1 domain family member 4 isoform X1JNK Interacting Protein (Scaffold protein)General transcription factor IIH subunitOxysterol-binding protein-related protein 2AFACT complex subunit POB3mRNA-decapping enzyme subunit 1Ran-binding proteinNumb-related protein 1Stress-activated map kinase-interacting protein 1Ran-binding protein 1, putativeInositol-3,4-bisphosphate 4-phosphatasePleckstrin homology domain containing O2Stress-activated map kinase interacting 1Mitogen-activated protein kinaseAGC/AKT protein kinaseProbable pleckstrin homology domain-containing family N member 1Acidic elicitin A1Rho GTPase-activating proteinPhospholipaseSwitch-associated protein 70Pleckstrin y domain-containing family H member 2mRNA-decapping enzyme 1BEG:23E12.2, isoform AUnc-112-related proteinUncharacterized protein, isoform AFACT complex subunit SSRP1FACT complex subunit SSRP1OPY1p proteinAGC protein kinaseMitogen-activated protein kinasePhosphatidylinositol 3-kinase 2Switch-associated protein 70AGC/RSK/RSKP90 protein kinaseDynein beta chainBRag/Iqsec/Schizo related Arf GEF family memberFACT complex subunit POB3AT4g11790/T5C23_220Dos, isoform AAdaptin earbinding coat-associated protein 2 (Necap-2) isoformArf-GAP with ANK repeat and PH domain-containing protein cnt-2Muscle M-line assembly protein unc-89-like ProteinCnkGTPase-activating protein pac-1Protostome-specific GEF, isoform EEXOCyst componentRan GTPase-activating protein, putativeRho GTPase-activating proteinSignal transducing adaptor family member 2FACT complex subunit POB3Nuclear protein export protein Yrb2Spermitin, isoform BFERM domain containing 4ASterol 3-beta-glucosyltransferasePleckstrin homology domain-containing family G member 6TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1Tyrosine-protein kinaseSyntrophin alpha 1Inorganic pyrophosphatase, putativePleckstrin-like domain-containing proteinUncharacterized protein, isoform Asesquipedalian-1-likeCRE-MIG-10 proteinInner membrane complex sub-compartment protein 3Unplaced genomic scaffold supercont2.1, whole genome shotgun sequenceBinding proteinPhosphoinositide 3-phosphatasetarget of rapamycin complex 2 subunit MAPKAP1 isoform X3TIAM (Mammalian Tumor Invasion And Metastasis factor) homologGD13075Nuclear Pore complex ProteinVacuolar protein-sorting-associated protein 36Inactive tyrosine-protein kinase kin-32TBC (Tre-2/Bub2/Cdc16) domain familyProtein CBR-STN-1Uncharacterized protein, isoform BSerine/threonine-protein kinase dkf-1FERM domain (Protein4.1-ezrin-radixin-moesin) familyTBC (Tre-2/Bub2/Cdc16) domain familyCDC-42 Guanine nucleotide Exchange FactorSterol 3-beta-glucosyltransferaseFERM domain (Protein4.1-ezrin-radixin-moesin) familyProtein kinase D4Phosphatidylinositol3,4-bisphosphate 4-phosphataseActin-binding protein anillin-like ProteinRelated to OSH3-Member of oxysterol-binding protein familyUncharacterized protein, isoform BPH domain-containing endocytic-trafficking adaptor 1Related to Stress-activated map kinase interacting protein 1pleckstrin homology domain-containing family A member 3Uncharacterized protein, isoform BUncharacterized proteinUncharacterized proteinRho1 guanine nucleotide exchange factor TUS1Uncharacterized protein, isoform AVacuolar sorting proteinWGS project CABT00000000 data, contig 2.21Vacuolar protein sorting-associated protein 36Kinesin, putativeExocyst complex componentMyosin 28B1, isoform BVacuolar sorting proteinProtein CBG09025Serine/threonine-protein kinaseDynaminFERM domain (Protein4.1-ezrin-radixin-moesin) familySHC-transforming protein 4disabled homolog 1 isoform X5Protein CBG20227Ran-specific GTPase-activating protein 1Uncharacterized proteinAdaptin ear-binding coat-associated protein 2 family proteinYLR072Wp proteinPutative rac serine-threonine kinaseDownstream of kinaseProtein CBG02248Pleckstrin homology (PH) and lipid-binding START domains-containing proteinAGAP011491-PACRE-TAG-318 proteinVacuolar protein sorting-associated protein 36Syntrophin, alpha 1Unconventional myosin heavy chain 6Serine/threonine protein kinase ppk21, putativeHeavy chain, Unconventional MyosinSterol 3-beta-glucosyltransferaseRTT106p Histone chaperoneMyosin 28B1, isoform BProtein kinase domain containing proteinUncharacterized proteinMotor AXon guidancePhosphoinositide phospholipase CTBC (Tre-2/Bub2/Cdc16) domain familyGuanine nucleotide exchange factor UNC-73AUncharacterized proteinOxysterol-binding protein-like 7PH domain containing proteinPleckstrin homology (PH) domain-containing proteinPhosphatidylinositol-3-phosphatase myotubularin-2dynamin-3-like isoform X2NECAP endocytosis-associated 1WGS project CABT00000000 data, contig 2.5Nucleoporin nup61Protein CBG23324target of rapamycin complex 2 subunit MAPKAP1 isoform X3Protein CBG14242Bud site selection protein 4Nuclear pore complex protein Nup50Adaptin ear-binding coat-associated protein, putativeGD20635PH-protein kinase domain containing proteinSerine/threonine protein kinasePH-protein kinase domain containing proteinSerine/threonine protein kinaseBPH1p ProteinDownstream of kinaseTBC (Tre-2/Bub2/Cdc16) domain familyArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3SH2B adaptor protein 3Atypical/BCR protein kinaseExocyst complex componentRegulator of G-protein signaling locoProtein kinase domain containing proteinPhosphatidylinositol transfer protein 2FACT complex subunit SSRP1TBC (Tre-2/Bub2/Cdc16) domain familyPutative GDP-GTP exchange factorSerine/threonine protein kinase, putativeNon-specific serine/threonine protein kinaseMiro family protein1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gammaCoroninQuattroPhosphoinositide phospholipase CFERM domain (Protein4.1-ezrin-radixin-moesin) familyUncharacterized proteinRho GTPase Activating proteinSHC-transforming protein homolog 1Rhotekin 2Uncharacterized proteinPH domain containing proteinGD19751Uncharacterized proteinPredicted proteinFACT complex subunit SSRP1Oxysterol-binding proteinPhosphoinositide phospholipase CTyrosine-protein kinaseUncharacterized proteinHistone chaperone Rttp106-like, putativeHypothetical_protein_-_conservedProtein kinase domain containing proteinSrc kinase associated phosphoprotein 1Serine/threonine protein kinase 3/4, putativeProtein expandedUncharacterized proteinp21-activated kinase, putativetensinNucleosome binding factor SPN, SPT16 subunitProtein kinase domain containing proteinGTP exchange factor for ARFs 1WASP (Actin cytoskeleton modulator) homologHomer scaffold protein 1SH2B adaptor protein 3Kinesin protein unc-104KinesinUncharacterized proteinAnillin-like protein 1RIKEN cDNA 1700003H04 geneTectonin beta-propeller repeat-containing protein 1Src kinase associated phosphoprotein 1Tectonin beta-propeller repeat-containing protein 1Pleckstrin domain-containing family J member 1Vacuolar protein sorting-associated protein 13CSerine/threonine protein kinasepleckstrin homology domain-containing family A member 2 isoform X2GM16509Serine/threonine-protein kinase, putativeSerine/threonine-protein kinase dkf-2Probable serine/threonine-protein kinase DDB_G0272282Vacuolar protein-sorting-associated protein 36EPS8-like 3Sorting nexin-17 homologTranscription initiation factor TFIIH subunit 1PH domain leucine-rich repeat-containing protein phosphatase 1Amyloid beta (A4) precursor protein-binding, family B, member 2bVacuolar protein sorting protein 36 Vps36/EAP30/Vps36 family, putativeUncharacterized proteinCoactivator-associated arginine methyltransferase 1,-likeSerine/threonine-protein kinase pakCPH and Rap-GAP domain-containing protein DDB_G0271806Virus Induced Reporter OffNuclear Pore complex ProteinPredicted proteinRan-binding protein 3Si:ch73-111k22.3Uncharacterized proteinUNC-34Basic proline-rich protein, putativeIntegrin beta-1-binding protein 1RAN binding protein 1Uncharacterized proteinTarget of rapamycin complex 2 subunit MAPKAP1AGAP012332-PAUncharacterized proteinMyotubularin-related protein 9Uncharacterized proteinUncharacterized proteinPleckstrin homology domain containing A2Collagen type IV alpha-3-binding proteinMyosin XVBPredicted proteinUncharacterized proteinDip13 beta, putativeUncharacterized proteinPutative Rho guanine nucleotide exchange factor FGD-1mRNA DeCAPping enzymeUncharacterized proteinSerine/threonine-protein kinase CLA4ESCRT-II complex subunit VPS36Histone-arginine methyltransferase CARM1PH-protein kinase domain containing proteinPhosphoinositide phospholipase CSerine/threonine-protein kinase NrkA1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gammaRho guanine nucleotide exchange factor 25Vacuolar protein sorting protein (Vps36), putativeBinding proteinKinesin, putativeFERM domain containing proteinAmyloid beta precursor protein binding family B member 1Predicted proteinPredicted proteinNuclear pore complex protein NUP50AGTPase-activating protein testicular GAP1E3 SUMO-protein ligase RanBP2-likeArfGAP with GTPase domain, ankyrin repeat and PH domain 2FACT complex subunit POB3Ran-binding protein (RanBP), putativeNuclear pore complex protein Nup50FE65-like proteinUncharacterized proteinUncharacterized proteinBud site selection protein BUD4sprouty-related, EVH1 domain-containing protein 2-likeProtein CBG15745Uncharacterized proteinSprouty-related, EVH1 domain containing 1CCM2-like scaffold proteinRANBP3 isoform 10Uncharacterized proteinDynamin 2bUncharacterized proteinUncharacterized proteinYALI0F15719pChromosome undetermined SCAF14530, whole genome shotgun sequenceYALI0F15719pUncharacterized proteinMannosyltransferaseRho guanine nucleotide exchange factor (GEF) 10RHo Guanine nucleotide exchange FactorRho guanine nucleotide exchange factor 10-like ProteinSyntrophin alpha 1Ran-binding protein (RanBP), putativeWW domain-containing protein tag-325Uncharacterized proteinADP ribosylation factor, putativeSorting nexin-31Src kinase-associated phosphoprotein 1Non-specific serine/threonine protein kinaseCARMIL (Capping, ARp2/3, Myosin I Linker protein) homologBEACH domain-containing protein C1Phosphoinositide phospholipase COxysterol-binding protein related proteinUncharacterized proteinTBC (Tre-2/Bub2/Cdc16) domain familyRho guanine nucleotide exchange factor 25Guanine nucleotide exchange factor Cdc24 homologue, putativeTyrosine-protein kinaseWiskott-Aldrich syndrome, likeGD21193ADR388CpAGAP003924-PAPutative phosphatidylinositol-3-phosphate binding proteinProtein CBG15618Eps8 like 1bPutative peptidyl-prolyl cis-trans isomeraseRho GTPase-activating protein (RhoGAP), putativeKinase, AGC MASTVacuolar protein sorting protein, putativeGuanine nucleotide exchange factor UNC-73BIQ motif and Sec7 domain 2Uncharacterized proteinRho GTPase activating protein 15Predicted proteinAnkyrin repeat-containing protein kinase APleckstrin homology like domain family B member 1Phosphoinositide phospholipase CPredicted proteinOxysterol-binding protein-like 9Uncharacterized proteinSH2B adapter protein 2FACT complex subunit POB3Uncharacterized proteinUncharacterized proteinTBC1 domain family member 9Uncharacterized proteinDCC-interacting protein 13-alpha-likeKinesin-3 motor proteinUncharacterized proteinamyloid beta A4 precursor protein-binding family B member 1-interacting protein-like isoform X3FI17948p1Uncharacterized proteinUncharacterized proteinAssociated with RAN (Nuclear import/export) functionSi:dkey-40c11.1Predicted proteinPleckstrin homology-like domain, family B, member 2aUncharacterized proteinUncharacterized proteinNuclear pore complex protein Nup50Predicted proteinRanBP1 domain containing proteinRanBP1 domain containing proteinUncharacterized proteinUncharacterized proteinSHC (Src homology 2 domain-containing)-transforming protein 2TFIIH/NER complex subunitUncharacterized proteinSMEK (Dictyostelium Suppressor of MEK null) homologInsulin receptor substrate 1-AMMS19 nucleotide excision repair protein-like proteinPutative Sprouty-related, EVH1 domain-containing proteinUncharacterized proteinUncharacterized proteinNucleoporinProtein loc100159627 isoform 1Predicted proteinRan-specific GTPase-activating proteinFamily with sequence similarity 43 member BGM23249pUncharacterized proteinYALI0B07623pPH domain protein (AFU_orthologue AFUA_3G13830)Uncharacterized proteinBud site selection protein 4 homologextensin isoform X1Chromosome 7, whole genome shotgun sequenceLOC100124981 proteinUncharacterized proteinNuclear pore complex protein Nup50Uncharacterized proteinUncharacterized proteinPleckstrin homology domain containing proteinUncharacterized proteinYALI0D12540puncharacterized protein LOC100181754Insulin receptor SubsTrate homologswitch-associated protein 70-like isoform X1Uncharacterized proteinUncharacterized proteinRab_C103 proteinPutative surface protein bspA-likePutative actin binding protein anillinPleckstrin homology domain-containing family B member 2Uncharacterized proteinactin filament-associated protein 1 isoform X1YALI0B12452pUncharacterized proteinuncharacterized protein LOC778851 isoform X2Uncharacterized proteinUncharacterized proteinPredicted proteinDynamin 2Non-specific serine/threonine protein kinaseNon-specific serine/threonine protein kinaseUncharacterized proteinDocking protein 2Uncharacterized proteinFERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)insulin receptor substrate 1-likeInsulin receptor substrate 1pleckstrin-2 isoform X2FACT complex subunit SSRP1FACT complex subunit SSRP1Uncharacterized proteinPhosphoinositide phospholipase CPhosphoinositide phospholipase CRho guanine nucleotide exchange factor 10Protein VASP homolog1-phosphatidylinositol 4,5-bisphosphate phosphodiesteraseUncharacterized proteinRho GTPase-activating protein gacEEUncharacterized proteinDecapping mRNA 1AUncharacterized protein3-phosphoinositide-dependent protein kinase 1Predicted proteinUncharacterized proteinCDC42 binding protein kinase betaRAB GTPase-activating protein, putative1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gammaPredicted proteinCyclic GMP-binding protein DPredicted proteinPredicted proteinGuanine exchange factor for Rac 30Predicted proteinWiscott-Aldrich syndrome proteinUncharacterized proteinUDP-sugar-dependent glycosyltransferase 52Rho GTPase-activating protein gacJJUncharacterized proteinUncharacterized proteinUDP-sugar-dependent glycosyltransferase 52Uncharacterized proteinUDP-sugar-dependent glycosyltransferase 52Uncharacterized proteinG-protein subunit alpha 3Uncharacterized proteinPhospholipase D BSca1 complex protein phrGeneral transcription factor IIH subunit 1rho GTPase-activating protein 26BEACH domain-containing protein lvsAPhosphoinositide phospholipase CUncharacterized proteinAAR091WpUncharacterized proteinPutative wiskott-aldrich syndrome-like aUncharacterized proteinUncharacterized proteinExocyst complex component 8Uncharacterized proteinPutative sorting nexin-29Uncharacterized proteinDrosophila SOS homologExocyst complex component EXO84Sterol 3-beta-glucosyltransferaseSorting nexin-17Uncharacterized proteinAFR725CpUncharacterized proteinTBC1 domain family member 2B-likeUncharacterized proteinUncharacterized proteinUncharacterized proteinBeta-1-syntrophinPleckstrin homology domain-containing family A member 8Myotubularin-related protein 6Oxysterol-binding protein-domain-containing proteinJnk interacting protein, putativeTyrosine-protein phosphatase 1Tyrosine-protein kinaseDynamin-2AClass VII unconventional myosinOxysterol-binding proteinCyclin-B1-3AER092WpcDNA FLJ54163, highly similar to Centaurin-alpha 1Vacuolar protein sorting protein (Vps36), putativeUncharacterized proteinTyrosine-protein kinaseYALI0C14828pRho GTPase-activating protein 20Uncharacterized proteinUncharacterized proteinVacuolar protein-sorting-associated protein 36Predicted proteinSubunit of ESCRT-II complexUncharacterized proteinDynamin-related GTPaseEpidermal growth factor receptor kinase substrate 8Uncharacterized proteinUncharacterized proteinEAP30/Vps36 family-domain-containing proteinUncharacterized proteinPhosphoinositide phospholipase CRab-GTPase-TBC domain-domain-containing proteinUncharacterized proteinUncharacterized proteinDynamin-1Phosphoinositide phospholipase CEAP30/Vps36 family, putativeExocyst complex component EXO84PeptidaseMotor AXon guidanceBand 4.1-like protein 5Uncharacterized proteinFERM domain-containing 3band 4.1-like protein 4 isoform X1IQ motif and Sec7 domain 3aIQ motif and SEC7 domain-containing protein 2 isoform X3Predicted proteinUncharacterized proteinUncharacterized proteinRho GTPase-activating protein 20-like ProteinArf guanine nucleotide exchange factor sec74Uncharacterized proteinPredicted proteinPredicted proteinVillidinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinFERM domain-containing 3FERM, ARH/RhoGEF and pleckstrin domain protein 2Predicted proteincAMP-dependent protein kinase catalytic subunit, putativeHomer, putativeRho guanine nucleotide exchange factor 17, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinArfGAP with GTPase domain, ankyrin repeat and PH domain 2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized PH domain-containing protein C19A8.02Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUNC-112-Interacting Guanine nucleotide exchange factorUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinIQ motif and Sec7 domain 2Switching B cell complex subunit SWAP70Uncharacterized proteinAnillin, actin-binding proteinUncharacterized proteinEzrinRho GTPase-activating protein 20bDAB adaptor protein 2Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein (Fragment)Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinRan-specific GTPase-activating proteinUncharacterized proteinZgc:110468 proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinNeCAP (NECAP) endocytosis associated protein homologUncharacterized proteinUncharacterized proteinPredicted proteinIL2-inducible T cell kinaseUncharacterized proteinUncharacterized proteinSi:dkey-172j4.3Phospholipase C gamma 1Nos1ap proteinUncharacterized proteinUncharacterized proteinOs08g0404400 proteinUncharacterized proteinSwitch-associated protein 70-like ProteinUncharacterized proteinRanBP1 domain containing proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein C1610.01Multisubstrate adapter protein soc-1Uncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinTarget of rapamycin complex 2 subunit MAPKAP1-like ProteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinTBC1 domain family member 1Uncharacterized proteinUncharacterized proteinAGAP008316-PAUncharacterized proteinPleckstrin homology domain-containing family J member 1-like ProteinUncharacterized proteinNuclear pore complex component NPAP60L/NUP50, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinMeiotic expression up-regulated protein 6Uncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinUncharacterized protein (Fragment)Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinRas association (RalGDS/AF-6) and pleckstrin homology domains 1Uncharacterized proteinUncharacterized proteinUncharacterized proteinDEF6 guanine nucleotide exchange factor cUncharacterized proteinProtein CBR-UNC-34Rhotekin 2bPredicted proteinDivision mal foutue 1 proteinUncharacterized proteinSi:ch211-122h15.4Expressed proteinUncharacterized proteinAGAP010456-PAUncharacterized proteinPH domain containing proteinuncharacterized protein LOC100187308 isoform X1Uncharacterized proteinMeiotically up-regulated gene 183 proteinProtein CBR-DYC-1Uncharacterized proteinArfGAP with dual PH domains 1-likeUncharacterized proteinUncharacterized proteinAGC family protein kinasecAMP-dependent protein kinase catalytic subunit, putativeBeige protein homolog 1Neurobeachin/beige protein, putativeBEACH domain-containing protein lvsDUncharacterized proteinYL1 nuclear protein Cterminal domain-containing proteinUncharacterized PH domain-containing protein PB16A4.02cUncharacterized proteinUncharacterized proteinUncharacterized PH domain-containing protein PB16A4.02cRan-binding protein 1 homolog aUncharacterized proteinYL1 nuclear protein Cterminal domain-containing proteinUncharacterized proteinUncharacterized proteinRan-binding protein 1 homolog aDocking protein 2Uncharacterized proteinDocking protein 2Arf-GAP with dual PH domain-containing protein 1Mitogen-activated protein kinase associated protein 1MannosyltransferaseUncharacterized proteinRAN binding protein 1Uncharacterized proteinUncharacterized proteinUncharacterized proteinCollagen, type IV, alpha 3 (Goodpasture antigen)-binding protein bGoodpasture antigen-binding protein, putativePredicted proteinUncharacterized proteinAmyloid beta precursor protein binding family A member 3Uncharacterized proteinUncharacterized proteinUncharacterized proteinPhosphoinositide phospholipase CPhosphoinositide phospholipase CUncharacterized proteinUncharacterized proteinRho guanine nucleotide exchange factor (GEF) 26Uncharacterized proteinUncharacterized proteinPhosphoinositide phospholipase CUncharacterized proteinAGC family protein kinaseUncharacterized proteinUncharacterized proteinUncharacterized proteinSi:ch211-248g20.5Uncharacterized proteinNucleoside diphosphate kinasePH and Rap-GAP domain-containing protein DDB_G0271806Chromosome 15, whole genome shotgun sequencePredicted proteinUncharacterized proteinProtein CARMILPredicted proteinGuanine exchange factor for Rac 30Phosphoinositide phospholipase CGTPase-activating protein BEM2Uncharacterized proteinPredicted proteinProbable serine/threonine-protein kinase roco5Predicted proteinUncharacterized proteinRas GTPase-activating protein gap-1Predicted proteinPredicted proteinUncharacterized proteinGuanine exchange factor for Rac 30Tyrosine-protein kinaseTyrosine-protein kinaseBEACH domain-containing protein lvsBVacuolar protein-sorting-associated protein 36Uncharacterized proteinNeurobeachin/beige protein, putativeUncharacterized proteinChromosome 19, whole genome shotgun sequenceAGC family protein kinaseUncharacterized proteinUncharacterized proteinPhosphoinositide phospholipase CPutative histone-arginine methyltransferase CARMER-like ProteinUncharacterized proteinpleckstrin homology domain-containing family A member 8 isoform X1Predicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinRoco6, ROCO family proteinUncharacterized proteinPredicted proteinPredicted proteinPH domain-containing protein DDB_G0287875Uncharacterized proteinRho-associated protein kinase let-502Predicted proteinPredicted proteinUncharacterized proteinUncharacterized proteinPH domain containing proteinFERM domain-containing protein AUncharacterized proteinUncharacterized proteinPredicted proteinEPS8 like 1Sterol 3-beta-glucosyltransferaseHistonearginine N-methyltransferaseDip13 beta, putativeUncharacterized proteinKRIT 1 (Krev interaction trapped/cerebral cavernous malformation 1) homologWiskott-Aldrich syndromeOxysterol-binding proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinESCRT-II subunit proteinUncharacterized proteinPleckstrin 2Uncharacterized proteinGTC2Diacylglycerol kinaseUncharacterized proteinDiacylglycerol kinasePredicted proteinPredicted proteinUncharacterized proteinFERM, RhoGEF and pleckstrin domain-containing protein, putativeUncharacterized proteinPhosphoinositide phospholipase CDiacylglycerol kinasePredicted proteinSHANK associated RH domain interactorChromosome 7, whole genome shotgun sequencePH and Rap-GAP domain-containing protein DDB_G0271806Diacylglycerol kinaseUncharacterized proteinUncharacterized proteinSH2B adapter protein 2Histonearginine N-methyltransferaseZinc finger protein, putativeBeta 1 syntrophin, putativeUncharacterized proteinGM06875pUncharacterized proteinArfGAP with SH3 domain, ankyrin repeat and PH domain 3Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinBcDNA.GH04637Uncharacterized proteinUncharacterized proteinG protein-coupled receptor kinaseProtein tyrosine kinase 2 beta, aUncharacterized proteinUncharacterized proteinProtein tyrosine kinase 2 beta, aProtein vav-1Uncharacterized proteinRac guanyl-nucleotide exchange factorPredicted proteinPredicted proteinPredicted proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinSerine/threonine-protein kinase ksg1Uncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinMyosin-M heavy chainVps51/Vps67 protein, putativeUncharacterized proteinPhosphoinositide phospholipase CKinesin-like proteinUncharacterized proteinUncharacterized proteinPredicted proteinExocyst complex component exo84Predicted proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPhosphoinositide phospholipase CPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein R02F2.2-like ProteinUncharacterized proteinUncharacterized proteinPredicted proteinPredicted proteinBEACH domain-containing protein lvsEMitogen-activated protein kinaseAGAP002982-PAUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinFERM domain-containing protein BUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinLD45876pRho GTPase activating protein, putativePredicted proteinUncharacterized proteinUncharacterized protein
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FunFam 174: epidermal growth factor receptor kinase substrate ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 2 Q08509 (/IPI) Q12929 (/IPI)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
 1 Q08509 (/IDA)
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
 1 Q08509 (/IDA)
Showing 1 to 5 of 5 entries

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Exit from mitosis GO:0010458
The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Rac protein signal transduction GO:0016601
A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Regulation of actin filament length GO:0030832
Any process that controls the length of actin filaments in a cell.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Dendritic cell migration GO:0036336
The movement of a dendritic cell within or between different tissues and organs of the body.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Barbed-end actin filament capping GO:0051016
The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Actin crosslink formation GO:0051764
The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Actin polymerization-dependent cell motility GO:0070358
A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
 1 Q08509 (/IMP)
Showing 1 to 10 of 28 entries

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Stereocilium GO:0032420
An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Ruffle membrane GO:0032587
The portion of the plasma membrane surrounding a ruffle.
 4 F1M3L7 (/ISS) Q12929 (/ISS) Q5R4H4 (/ISS) Q5R4H4 (/ISS)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
 2 F1M3L7 (/IDA) Q08509 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
 2 F1M3L7 (/IDA) Q08509 (/IDA)
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
 1 Q08509 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
 1 Q08509 (/IDA)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
 1 Q08509 (/ISO)
NMDA selective glutamate receptor complex GO:0017146
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.
 1 Q08509 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
 1 Q12929 (/HDA)
Showing 1 to 10 of 18 entries
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