The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 148: pleckstrin homology domain-containing family M mem...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8IWE5 (/IPI)
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
1 Q8IWE5 (/IDA)
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
1 Q80TQ5 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
1 Q8IWE5 (/IMP)
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
1 Q80TQ5 (/ISO)
Lysosome localization GO:0032418
Any process in which a lysosome is transported to, and/or maintained in, a specific location.
1 Q8IWE5 (/IMP)
Lysosome localization GO:0032418
Any process in which a lysosome is transported to, and/or maintained in, a specific location.
1 Q80TQ5 (/ISO)
Lysosome localization GO:0032418
Any process in which a lysosome is transported to, and/or maintained in, a specific location.
1 Q80TQ5 (/ISS)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
1 Q8IWE5 (/IMP)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
1 Q80TQ5 (/ISO)
Positive regulation of membrane tubulation GO:1903527
Any process that activates or increases the frequency, rate or extent of membrane tubulation.
1 Q8IWE5 (/IDA)
Positive regulation of membrane tubulation GO:1903527
Any process that activates or increases the frequency, rate or extent of membrane tubulation.
1 Q80TQ5 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
1 Q8IWE5 (/IDA)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
1 Q80TQ5 (/ISO)