CATH Superfamily 2.30.29.30
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".
FunFam 110: Docking protein 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
32 |
Q2MHE5 (/IPI)
Q2MHE5 (/IPI)
Q6PKX4 (/IPI)
Q6PKX4 (/IPI)
Q6PKX4 (/IPI)
Q6PKX4 (/IPI)
Q6PKX4 (/IPI)
Q6PKX4 (/IPI)
Q6PKX4 (/IPI)
Q6PKX4 (/IPI)
(22 more) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
32 |
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
(22 more) |
|
Regulation of neurotrophin TRK receptor signaling pathway GO:0051386
Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
|
4 | Q9P104 (/IMP) Q9P104 (/IMP) Q9P104 (/IMP) Q9P104 (/IMP) |
|
Transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169
A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | Q91ZM9 (/IPI) Q99KE3 (/IPI) |
|
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
|
2 | Q91ZM9 (/IDA) Q99KE3 (/IDA) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | Q99KE3 (/IDA) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
1 | Q91ZM9 (/IDA) |
|
Regulation of neurotrophin TRK receptor signaling pathway GO:0051386
Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
|
1 | Q91ZM9 (/ISO) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
32 |
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
Q6PKX4 (/TAS)
(22 more) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | A4IFJ7 (/IDA) |