The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Serralysin-like metalloprotease, C-terminal
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Leukotoxin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q7BHI8 (/IPI) Q7BHI8 (/IPI) Q7BHI8 (/IPI) Q7BHI8 (/IPI)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cytolysis by symbiont of host cells GO:0001900
Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
4 Q7BHI8 (/IMP) Q7BHI8 (/IMP) Q7BHI8 (/IMP) Q7BHI8 (/IMP)
Induction by symbiont of defense-related host calcium ion flux GO:0052391
The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
4 Q7BHI8 (/IMP) Q7BHI8 (/IMP) Q7BHI8 (/IMP) Q7BHI8 (/IMP)
Positive regulation of lymphocyte apoptotic process GO:0070230
Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.
4 Q7BHI8 (/IDA) Q7BHI8 (/IDA) Q7BHI8 (/IDA) Q7BHI8 (/IDA)
Toxin transport GO:1901998
The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 P16535 (/IMP) P16535 (/IMP) P16535 (/IMP) P16535 (/IMP)
Positive regulation of apoptotic DNA fragmentation GO:1902512
Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.
4 Q7BHI8 (/IDA) Q7BHI8 (/IDA) Q7BHI8 (/IDA) Q7BHI8 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 P16535 (/IMP) P16535 (/IMP) P16535 (/IMP) P16535 (/IMP)