The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"YVTN repeat-like/Quinoprotein amine dehydrogenase
".
FunFam 25: FIZZY-related 2 isoform 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
14 |
B1WCA1 (/IPI)
Q8L3Z8 (/IPI)
Q8L3Z8 (/IPI)
Q8VZS9 (/IPI)
Q9R1K5 (/IPI)
Q9R1K5 (/IPI)
Q9UM11 (/IPI)
Q9UM11 (/IPI)
Q9UM11 (/IPI)
Q9UM11 (/IPI)
(4 more) |
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
2 | O18402 (/IDA) Q9W4H9 (/IDA) |
There are 51 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
10 | O18402 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9W4H9 (/IDA) |
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
8 | Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) |
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
8 | Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) |
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
8 | Q9UM11 (/IGI) Q9UM11 (/IGI) Q9UM11 (/IGI) Q9UM11 (/IGI) Q9UM11 (/IGI) Q9UM11 (/IGI) Q9UM11 (/IGI) Q9UM11 (/IGI) |
Protein K11-linked ubiquitination GO:0070979
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
|
8 | Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) |
Signal transduction involved in G2 DNA damage checkpoint GO:0072425
A signal transduction process that contributes to a G2/M transition DNA damage checkpoint.
|
8 | Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) |
Regulation of mitotic cell cycle phase transition GO:1901990
Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.
|
8 | Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) |
Positive regulation of ubiquitin protein ligase activity GO:1904668
Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
|
8 | Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) |
Regulation of meiotic nuclear division GO:0040020
Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
|
7 | Q32L05 (/ISS) Q32L05 (/ISS) Q32L05 (/ISS) Q32L05 (/ISS) Q5H7B9 (/ISS) Q8UWJ6 (/ISS) Q8UWJ8 (/ISS) |
Regulation of exit from mitosis GO:0007096
Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
|
3 | Q5ACY4 (/IMP) Q5ACY4 (/IMP) Q5ACY4 (/IMP) |
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
2 | O18402 (/IMP) Q9W4H9 (/IMP) |
Regulation of mitotic nuclear division GO:0007088
Any process that modulates the frequency, rate or extent of mitosis.
|
2 | O18402 (/IMP) Q9W4H9 (/IMP) |
Eye-antennal disc morphogenesis GO:0007455
The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.
|
2 | O18402 (/IMP) Q9W4H9 (/IMP) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | Q9R1K5 (/IMP) Q9R1K5 (/IMP) |
Glial cell migration GO:0008347
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
|
2 | O18402 (/IMP) Q9W4H9 (/IMP) |
Multidimensional cell growth GO:0009825
The process in which a cell irreversibly increases in size in two or three
|
2 | Q8L3Z8 (/IMP) Q8L3Z8 (/IMP) |
Glial cell differentiation GO:0010001
The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.
|
2 | O18402 (/IDA) Q9W4H9 (/IDA) |
Trichome branching GO:0010091
Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.
|
2 | Q8L3Z8 (/IMP) Q8L3Z8 (/IMP) |
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | O18402 (/IMP) Q9W4H9 (/IMP) |
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
2 | Q9R1K5 (/ISO) Q9R1K5 (/ISO) |
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
2 | Q9R1K5 (/ISS) Q9R1K5 (/ISS) |
Positive regulation of exit from mitosis GO:0031536
Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
|
2 | O18402 (/IMP) Q9W4H9 (/IMP) |
Regulation of meiotic nuclear division GO:0040020
Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
|
2 | Q9R1K5 (/IDA) Q9R1K5 (/IDA) |
DNA endoreduplication GO:0042023
Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
|
2 | Q8L3Z8 (/IMP) Q8L3Z8 (/IMP) |
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | Q9R1K5 (/ISO) Q9R1K5 (/ISO) |
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | Q9R1K5 (/ISS) Q9R1K5 (/ISS) |
Lens fiber cell differentiation GO:0070306
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
|
2 | Q9R1K5 (/IMP) Q9R1K5 (/IMP) |
Signal transduction involved in G2 DNA damage checkpoint GO:0072425
A signal transduction process that contributes to a G2/M transition DNA damage checkpoint.
|
2 | Q9R1K5 (/ISO) Q9R1K5 (/ISO) |
Signal transduction involved in G2 DNA damage checkpoint GO:0072425
A signal transduction process that contributes to a G2/M transition DNA damage checkpoint.
|
2 | Q9R1K5 (/ISS) Q9R1K5 (/ISS) |
Negative regulation of cell aging GO:0090344
Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
|
2 | Q9R1K5 (/IMP) Q9R1K5 (/IMP) |
Positive regulation of ubiquitin protein ligase activity GO:1904668
Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
|
2 | Q9R1K5 (/ISO) Q9R1K5 (/ISO) |
Positive regulation of ubiquitin protein ligase activity GO:1904668
Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
|
2 | Q9R1K5 (/ISS) Q9R1K5 (/ISS) |
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
|
1 | Q9W1F6 (/IEP) |
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
|
1 | Q8VZS9 (/IMP) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | C9WAL8 (/RCA) |
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
|
1 | C9WAL8 (/RCA) |
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
1 | C9WAL8 (/RCA) |
Endosperm development GO:0009960
The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.
|
1 | C9WAL8 (/RCA) |
Trichome branching GO:0010091
Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.
|
1 | C9WAL8 (/ISA) |
Maintenance of shoot apical meristem identity GO:0010492
The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
|
1 | Q8VZS9 (/IMP) |
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
|
1 | C9WAL8 (/ISA) |
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q9W4H9 (/IDA) |
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
1 | Q9W1F6 (/IGI) |
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
1 | Q5H7B9 (/IMP) |
Positive regulation of DNA endoreduplication GO:0032877
Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.
|
1 | Q8VZS9 (/IMP) |
DNA endoreduplication GO:0042023
Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
|
1 | C9WAL8 (/ISA) |
Cell cycle G1/S phase transition GO:0044843
The cell cycle process by which a cell in G1 phase commits to S phase.
|
1 | Q09649 (/IMP) |
Meristem development GO:0048507
The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.
|
1 | C9WAL8 (/RCA) |
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
|
1 | Q09649 (/IGI) |
Response to other organism GO:0051707
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
|
1 | C9WAL8 (/RCA) |
Negative regulation of meiotic cell cycle process involved in oocyte maturation GO:1904145
Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
|
1 | Q5H7B9 (/IMP) |
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
8 | Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
8 | Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) Q9UM11 (/TAS) |
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
8 | Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) Q9UM11 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | O18402 (/IDA) Q09649 (/IDA) Q8VZS9 (/IDA) Q9W4H9 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q09649 (/IDA) Q8VZS9 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q9R1K5 (/ISO) Q9R1K5 (/ISO) |
Anaphase-promoting complex GO:0005680
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
|
2 | O18402 (/IDA) Q9W4H9 (/IDA) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
2 | O18402 (/IDA) Q9W4H9 (/IDA) |
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
|
2 | O18402 (/IDA) Q9W4H9 (/IDA) |
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
|
2 | O18402 (/IDA) Q9W4H9 (/IDA) |
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
2 | O18402 (/IDA) Q9W4H9 (/IDA) |
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
2 | Q9R1K5 (/ISO) Q9R1K5 (/ISO) |