The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"YVTN repeat-like/Quinoprotein amine dehydrogenase
".
FunFam 224: cell division cycle protein 20 homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | Q12834 (/IPI) Q12834 (/IPI) Q12834 (/IPI) Q12834 (/IPI) Q3E906 (/IPI) Q62623 (/IPI) Q9JJ66 (/IPI) Q9S7H3 (/IPI) Q9S7I8 (/IPI) Q9SZA4 (/IPI) |
|
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
4 | Q12834 (/IPI) Q12834 (/IPI) Q12834 (/IPI) Q12834 (/IPI) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
4 | Q12834 (/IPI) Q12834 (/IPI) Q12834 (/IPI) Q12834 (/IPI) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
3 | Q3E906 (/IPI) Q9S7I8 (/IPI) Q9SZA4 (/IPI) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
2 | Q24044 (/IDA) Q6NR32 (/IDA) |
|
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | Q9JJ66 (/ISO) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q9JJ66 (/ISO) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
1 | Q62623 (/IPI) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
1 | Q9JJ66 (/ISO) |
There are 33 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of synaptic plasticity GO:0031915
A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
7 | Q12834 (/ISS) Q12834 (/ISS) Q12834 (/ISS) Q12834 (/ISS) Q5H7C0 (/ISS) Q5H7C0 (/ISS) Q62623 (/ISS) |
|
Positive regulation of synapse maturation GO:0090129
Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
|
7 | Q12834 (/ISS) Q12834 (/ISS) Q12834 (/ISS) Q12834 (/ISS) Q5H7C0 (/ISS) Q5H7C0 (/ISS) Q62623 (/ISS) |
|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
6 | Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) Q24044 (/IDA) Q6NR32 (/IDA) |
|
Positive regulation of ubiquitin protein ligase activity GO:1904668
Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
|
6 | Q24044 (/ISS) Q5H7C0 (/ISS) Q5H7C0 (/ISS) Q62623 (/ISS) Q6NR32 (/ISS) Q9JJ66 (/ISS) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Mitotic spindle assembly checkpoint GO:0007094
A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
4 | Q24044 (/IMP) Q5H7C0 (/IMP) Q5H7C0 (/IMP) Q6NR32 (/IMP) |
|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Regulation of mitotic cell cycle phase transition GO:1901990
Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Positive regulation of ubiquitin protein ligase activity GO:1904668
Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
|
4 | Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) |
|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
2 | Q24044 (/HMP) Q6NR32 (/HMP) |
|
Regulation of exit from mitosis GO:0007096
Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
|
2 | Q24044 (/TAS) Q6NR32 (/TAS) |
|
Female meiosis I GO:0007144
The cell cycle process in which the first meiotic division occurs in the female germline.
|
2 | Q24044 (/IGI) Q6NR32 (/IGI) |
|
Female meiosis II GO:0007147
The cell cycle process in which the second meiotic division occurs in the female germline.
|
2 | Q24044 (/IMP) Q6NR32 (/IMP) |
|
Regulation of proteolysis GO:0030162
Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
|
2 | Q24044 (/TAS) Q6NR32 (/TAS) |
|
Protein catabolic process GO:0030163
The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | Q24044 (/IMP) Q6NR32 (/IMP) |
|
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
|
2 | Q24044 (/IMP) Q6NR32 (/IMP) |
|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
2 | Q24044 (/ISS) Q6NR32 (/ISS) |
|
Negative regulation of necrotic cell death GO:0060547
Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
|
2 | Q24044 (/IMP) Q6NR32 (/IMP) |
|
Neuronal stem cell population maintenance GO:0097150
Any process in by an organism or tissue maintains a population of neuronal stem cells.
|
2 | Q24044 (/IMP) Q6NR32 (/IMP) |
|
Positive regulation of meiotic cell cycle process involved in oocyte maturation GO:1904146
Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
|
2 | Q5H7C0 (/IMP) Q5H7C0 (/IMP) |
|
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
|
1 | Q9JJ66 (/IGI) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q62623 (/IMP) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q9JJ66 (/ISO) |
|
Anaphase-promoting complex-dependent catabolic process GO:0031145
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
|
1 | Q9JJ66 (/ISO) |
|
Positive regulation of synaptic plasticity GO:0031915
A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
|
1 | Q9JJ66 (/IDA) |
|
Regulation of meiotic nuclear division GO:0040020
Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
|
1 | Q9JJ66 (/IGI) |
|
Regulation of dendrite development GO:0050773
Any process that modulates the frequency, rate or extent of dendrite development.
|
1 | Q62623 (/IMP) |
|
Regulation of dendrite development GO:0050773
Any process that modulates the frequency, rate or extent of dendrite development.
|
1 | Q9JJ66 (/ISO) |
|
Positive regulation of synapse maturation GO:0090129
Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
|
1 | Q9JJ66 (/IDA) |
|
Mitotic spindle assembly GO:0090307
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.
|
1 | Q9JJ66 (/IMP) |
|
Positive regulation of ubiquitin protein ligase activity GO:1904668
Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
|
1 | Q9JJ66 (/ISO) |
There are 25 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) Q3E906 (/IDA) Q9S7I8 (/IDA) Q9SZA4 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) Q12834 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) Q12834 (/TAS) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
3 | Q24044 (/IDA) Q62623 (/IDA) Q6NR32 (/IDA) |
|
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
2 | Q24044 (/IDA) Q6NR32 (/IDA) |
|
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
2 | Q24044 (/TAS) Q6NR32 (/TAS) |
|
Anaphase-promoting complex GO:0005680
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
|
2 | Q24044 (/IDA) Q6NR32 (/IDA) |
|
Anaphase-promoting complex GO:0005680
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
|
2 | Q24044 (/ISS) Q6NR32 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q24044 (/TAS) Q6NR32 (/TAS) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
2 | Q24044 (/TAS) Q6NR32 (/TAS) |
|
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
|
2 | Q24044 (/IDA) Q6NR32 (/IDA) |
|
Mitotic checkpoint complex GO:0033597
A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.
|
2 | Q9S7I8 (/IPI) Q9SZA4 (/IPI) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9JJ66 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9JJ66 (/ISO) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | Q9JJ66 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9JJ66 (/ISO) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q62623 (/IDA) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q9JJ66 (/ISO) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | Q54MZ3 (/HDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q62623 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q9JJ66 (/ISO) |
|
Cul4-RING E3 ubiquitin ligase complex GO:0080008
A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
|
1 | Q3E906 (/ISS) |