The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Kelch-type beta propeller
".
FunFam 2: Kelch-like family member 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | O95198 (/IPI) O95198 (/IPI) O95198 (/IPI) Q9UH77 (/IPI) Q9UH77 (/IPI) Q9UH77 (/IPI) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
4 | O95198 (/IDA) O95198 (/IDA) O95198 (/IDA) Q04652 (/IDA) |
Structural molecule activity GO:0005198
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
|
3 | Q9UH77 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
3 | O95198 (/IPI) O95198 (/IPI) O95198 (/IPI) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
2 | F1LZF0 (/ISS) Q8JZP3 (/ISS) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | Q8JZP3 (/ISO) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q8JZP3 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q8JZP3 (/ISO) |
There are 31 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
9 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1LZF0 (/ISS) F1MBP6 (/ISS) O95198 (/ISS) O95198 (/ISS) O95198 (/ISS) Q5REP9 (/ISS) |
Post-translational protein modification GO:0043687
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
|
6 | O95198 (/TAS) O95198 (/TAS) O95198 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) |
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
5 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1MBP6 (/ISS) Q5REP9 (/ISS) |
Ion homeostasis GO:0050801
Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
|
5 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1MBP6 (/ISS) Q5REP9 (/ISS) |
Renal sodium ion absorption GO:0070294
A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
|
5 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1MBP6 (/ISS) Q5REP9 (/ISS) |
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
|
5 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1MBP6 (/ISS) Q5REP9 (/ISS) |
Distal tubule morphogenesis GO:0072156
The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.
|
5 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1MBP6 (/ISS) Q5REP9 (/ISS) |
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
4 | Q8JZP3 (/IDA) Q9UH77 (/IDA) Q9UH77 (/IDA) Q9UH77 (/IDA) |
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
3 | Q9UH77 (/IDA) Q9UH77 (/IDA) Q9UH77 (/IDA) |
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
3 | Q9UH77 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) |
Ion homeostasis GO:0050801
Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
|
3 | Q9UH77 (/IMP) Q9UH77 (/IMP) Q9UH77 (/IMP) |
Selective autophagy GO:0061912
The macroautophagy process in which specific structures are targeted by the autophagy process.
|
3 | Q9UH77 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) |
Renal sodium ion absorption GO:0070294
A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
|
3 | Q9UH77 (/IMP) Q9UH77 (/IMP) Q9UH77 (/IMP) |
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
|
3 | Q9UH77 (/IDA) Q9UH77 (/IDA) Q9UH77 (/IDA) |
Distal tubule morphogenesis GO:0072156
The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.
|
3 | Q9UH77 (/IMP) Q9UH77 (/IMP) Q9UH77 (/IMP) |
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
1 | E0CZ16 (/ISO) |
Ovarian follicle cell migration GO:0007297
The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.
|
1 | Q04652 (/HMP) |
Ovarian nurse cell to oocyte transport GO:0007300
Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.
|
1 | Q04652 (/IMP) |
Female germline ring canal formation GO:0007301
Assembly of the intercellular bridges that connect the germ-line cells of a female cyst.
|
1 | Q04652 (/IDA) |
Female germline ring canal formation GO:0007301
Assembly of the intercellular bridges that connect the germ-line cells of a female cyst.
|
1 | Q04652 (/IMP) |
Cellularization GO:0007349
The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.
|
1 | Q04652 (/IMP) |
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | E0CZ16 (/ISO) |
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q04652 (/IMP) |
Oocyte karyosome formation GO:0030717
The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
|
1 | Q04652 (/IMP) |
Ovarian fusome organization GO:0030723
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.
|
1 | Q04652 (/IMP) |
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
|
1 | Q04652 (/HMP) |
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
|
1 | Q04652 (/IMP) |
Ion homeostasis GO:0050801
Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
|
1 | E0CZ16 (/ISO) |
Renal sodium ion absorption GO:0070294
A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
|
1 | E0CZ16 (/ISO) |
Protein K48-linked ubiquitination GO:0070936
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
|
1 | E0CZ16 (/ISO) |
Distal tubule morphogenesis GO:0072156
The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.
|
1 | E0CZ16 (/ISO) |
There are 18 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cul3-RING ubiquitin ligase complex GO:0031463
A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
|
9 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1LZF0 (/ISS) F1MBP6 (/ISS) O95198 (/ISS) O95198 (/ISS) O95198 (/ISS) Q5REP9 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | O95198 (/TAS) O95198 (/TAS) O95198 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | E0CZ16 (/ISS) E7F6F9 (/ISS) F1LZ52 (/ISS) F1MBP6 (/ISS) Q5REP9 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | F1LZF0 (/ISS) O95198 (/ISS) O95198 (/ISS) O95198 (/ISS) |
Cul3-RING ubiquitin ligase complex GO:0031463
A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
|
4 | Q8JZP3 (/IDA) Q9UH77 (/IDA) Q9UH77 (/IDA) Q9UH77 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q9UH77 (/IDA) Q9UH77 (/IDA) Q9UH77 (/IDA) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
3 | O95198 (/IDA) O95198 (/IDA) O95198 (/IDA) |
Cul3-RING ubiquitin ligase complex GO:0031463
A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
|
3 | Q9UH77 (/TAS) Q9UH77 (/TAS) Q9UH77 (/TAS) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
2 | F1LZF0 (/ISS) Q8JZP3 (/ISS) |
Stress fiber GO:0001725
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
|
1 | Q8JZP3 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8JZP3 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | E0CZ16 (/ISO) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
1 | Q8JZP3 (/ISO) |
Cul3-RING ubiquitin ligase complex GO:0031463
A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
|
1 | E0CZ16 (/ISO) |
Female germline ring canal inner rim GO:0035183
A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.
|
1 | Q04652 (/TAS) |
Female germline ring canal GO:0035324
An intercellular bridge that connects the germline cells of a female cyst.
|
1 | Q04652 (/IDA) |
Germline ring canal GO:0045172
Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.
|
1 | Q04652 (/IDA) |
Germline ring canal GO:0045172
Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.
|
1 | Q04652 (/TAS) |