The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"TolB, C-terminal domain
".
FunFam 26: hedgehog-interacting protein-like isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q7TN16 (/IPI) Q96QV1 (/IPI) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q96QV1 (/IDA) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q7TN16 (/ISO) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | Q7TN16 (/ISS) |
Hedgehog family protein binding GO:0097108
Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development.
|
1 | Q96QV1 (/IPI) |
Hedgehog family protein binding GO:0097108
Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development.
|
1 | Q7TN16 (/ISO) |
Showing 1 to 6 of 6 entries
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of signal transduction GO:0009968
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
|
6 | A0A0B5JK82 (/IDA) A0A2R8PZ08 (/IDA) A0A2R8Q4T0 (/IDA) A1A5I0 (/IDA) A7X2Z0 (/IDA) Q96QV1 (/IDA) |
Negative regulation of smoothened signaling pathway GO:0045879
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
|
6 | A0A0B5JK82 (/IMP) A0A2R8PZ08 (/IMP) A0A2R8Q4T0 (/IMP) A1A5I0 (/IMP) A7X2Z0 (/IMP) Q7TN16 (/IMP) |
Negative regulation of signal transduction GO:0009968
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
|
5 | A0A0B5JK82 (/IMP) A0A2R8PZ08 (/IMP) A0A2R8Q4T0 (/IMP) A1A5I0 (/IMP) A7X2Z0 (/IMP) |
Fin development GO:0033333
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
|
5 | A0A0B5JK82 (/IMP) A0A2R8PZ08 (/IMP) A0A2R8Q4T0 (/IMP) A1A5I0 (/IMP) A7X2Z0 (/IMP) |
Negative regulation of muscle organ development GO:0048635
Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
|
5 | A0A0B5JK82 (/IDA) A0A2R8PZ08 (/IDA) A0A2R8Q4T0 (/IDA) A1A5I0 (/IDA) A7X2Z0 (/IDA) |
Negative regulation of muscle organ development GO:0048635
Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
|
5 | A0A0B5JK82 (/IGI) A0A2R8PZ08 (/IGI) A0A2R8Q4T0 (/IGI) A1A5I0 (/IGI) A7X2Z0 (/IGI) |
Negative regulation of muscle organ development GO:0048635
Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
|
5 | A0A0B5JK82 (/IMP) A0A2R8PZ08 (/IMP) A0A2R8Q4T0 (/IMP) A1A5I0 (/IMP) A7X2Z0 (/IMP) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | Q7TN16 (/IDA) |
Neuroblast proliferation GO:0007405
The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
|
1 | Q7TN16 (/IGI) |
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
1 | Q7TN16 (/IMP) |
Showing 1 to 10 of 22 entries
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | A0A0B5JK82 (/ISS) A0A2R8PZ08 (/ISS) A0A2R8Q4T0 (/ISS) A1A5I0 (/ISS) A7X2Z0 (/ISS) |
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
5 | A0A0B5JK82 (/IDA) A0A2R8PZ08 (/IDA) A0A2R8Q4T0 (/IDA) A1A5I0 (/IDA) A7X2Z0 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | D3ZGL3 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q7TN16 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | D3ZGL3 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q7TN16 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | D3ZGL3 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q7TN16 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q7TN16 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q96QV1 (/ISS) |
Showing 1 to 10 of 12 entries