The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Neuraminidase 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Exo-alpha-sialidase activity GO:0004308
Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
15 A0JMM3 (/IDA) A0PJS4 (/IDA) A7MCG3 (/IDA) A7TUD4 (/IDA) A7TUD5 (/IDA) B8LF84 (/IDA) I3IS98 (/IDA) I3ITP7 (/IDA) Q1JPT6 (/IDA) Q4V9A4 (/IDA)
(5 more)
Exo-alpha-(2->3)-sialidase activity GO:0052794
Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.
8 Q64393 (/ISS) Q64627 (/ISS) Q99PW5 (/ISS) Q9JMH3 (/ISS) Q9JMH3 (/ISS) Q9JMH7 (/ISS) Q9JMH7 (/ISS) Q9UQ49 (/ISS)
Exo-alpha-sialidase activity GO:0004308
Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
4 Q9JMH3 (/ISO) Q9JMH3 (/ISO) Q9JMH7 (/ISO) Q9JMH7 (/ISO)
Exo-alpha-(2->8)-sialidase activity GO:0052796
Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.
4 Q99PW5 (/ISS) Q9JMH7 (/ISS) Q9JMH7 (/ISS) Q9UQ49 (/ISS)
Exo-alpha-sialidase activity GO:0004308
Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
2 Q9UQ49 (/TAS) Q9Y3R4 (/TAS)
Alpha-sialidase activity GO:0016997
Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.
2 Q9JMH7 (/ISO) Q9JMH7 (/ISO)
Exo-alpha-(2->3)-sialidase activity GO:0052794
Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.
2 O97859 (/IDA) Q9Y3R4 (/IDA)
Exo-alpha-(2->3)-sialidase activity GO:0052794
Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.
2 Q9JMH3 (/ISO) Q9JMH3 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9Y3R4 (/IPI)
Alpha-sialidase activity GO:0016997
Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.
1 Q9UQ49 (/IDA)
Exo-alpha-(2->8)-sialidase activity GO:0052796
Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.
1 O97859 (/IDA)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ganglioside metabolic process GO:0001573
The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
8 A0JMM3 (/IDA) A0PJS4 (/IDA) A7TUD5 (/IDA) B8LF84 (/IDA) I3IS98 (/IDA) I3ITP7 (/IDA) Q1JPT6 (/IDA) Q503Z4 (/IDA)
Ganglioside catabolic process GO:0006689
The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
7 Q64393 (/ISS) Q64627 (/ISS) Q99PW5 (/ISS) Q9JMH3 (/ISS) Q9JMH3 (/ISS) Q9JMH7 (/ISS) Q9JMH7 (/ISS)
Ganglioside catabolic process GO:0006689
The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
4 Q9JMH3 (/ISO) Q9JMH3 (/ISO) Q9JMH7 (/ISO) Q9JMH7 (/ISO)
Oligosaccharide catabolic process GO:0009313
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
4 Q9JMH3 (/ISO) Q9JMH3 (/ISO) Q9JMH7 (/ISO) Q9JMH7 (/ISO)
Oligosaccharide catabolic process GO:0009313
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
4 Q64393 (/ISS) Q64627 (/ISS) Q9JMH3 (/ISS) Q9JMH3 (/ISS)
Ganglioside catabolic process GO:0006689
The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
3 O97859 (/IDA) Q9UQ49 (/IDA) Q9Y3R4 (/IDA)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
2 Q9JMH7 (/ISO) Q9JMH7 (/ISO)
Glycosphingolipid metabolic process GO:0006687
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
2 Q9UQ49 (/TAS) Q9Y3R4 (/TAS)
Oligosaccharide catabolic process GO:0009313
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
2 Q9UQ49 (/IDA) Q9Y3R4 (/IDA)
Positive regulation of myotube differentiation GO:0010831
Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
2 Q9JMH3 (/ISO) Q9JMH3 (/ISO)
Positive regulation of myoblast differentiation GO:0045663
Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2 Q9JMH3 (/ISO) Q9JMH3 (/ISO)
Cellular oligosaccharide catabolic process GO:0051692
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.
2 Q9JMH3 (/ISO) Q9JMH3 (/ISO)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
1 Q9UQ49 (/IDA)
Positive regulation of myotube differentiation GO:0010831
Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
1 Q64627 (/IMP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 Q64627 (/IEP)
Positive regulation of myoblast differentiation GO:0045663
Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
1 Q64627 (/IDA)
Cellular oligosaccharide catabolic process GO:0051692
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.
1 Q9Y3R4 (/IDA)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 A7MCG3 (/IDA) A7TUD4 (/IDA) Q4V9A4 (/IDA) Q64627 (/IDA) Q6DEM9 (/IDA) Q9Y3R4 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
5 A0PJS4 (/IDA) A7TUD5 (/IDA) I3IS98 (/IDA) I3ITP7 (/IDA) Q503Z4 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q99PW5 (/ISS) Q9JMH7 (/ISS) Q9JMH7 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 A0JMM3 (/IDA) B8LF84 (/IDA) Q1JPT6 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9JMH3 (/ISO) Q9JMH3 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9JMH3 (/ISO) Q9JMH3 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 O97859 (/IDA) Q9UQ49 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9JMH7 (/ISO) Q9JMH7 (/ISO)
Catalytic complex GO:1902494
A protein complex which is capable of catalytic activity.
2 Q9JMH3 (/ISO) Q9JMH3 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q64627 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9Y3R4 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9Y3R4 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9UQ49 (/TAS)
Catalytic complex GO:1902494
A protein complex which is capable of catalytic activity.
1 Q9Y3R4 (/IDA)
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