The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cystine-knot cytokines
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 75: Follicle stimulating hormone beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
1 Q6QMG0 (/IDA)
Follicle-stimulating hormone receptor binding GO:0031762
Interacting selectively and non-covalently with a follicle-stimulating hormone receptor.
1 D2CJR2 (/ISS)
Lutropin-choriogonadotropic hormone receptor binding GO:0031775
Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor.
1 D2CJR2 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 D2CJR2 (/ISS)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
1 Q6QMG0 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q6QMG0 (/IGI)
Sex determination GO:0007530
Any process that establishes and transmits the specification of sexual status of an individual organism.
1 Q6QMG0 (/IGI)
Sex determination GO:0007530
Any process that establishes and transmits the specification of sexual status of an individual organism.
1 Q6QMG0 (/IMP)
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
1 Q6QMG0 (/IGI)
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
1 Q6QMG0 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 D2CJR2 (/ISS)
Positive regulation of androgen secretion GO:2000836
Any process that activates or increases the frequency, rate or extent of androgen secretion.
1 D2CJR2 (/ISS)
Positive regulation of estradiol secretion GO:2000866
Any process that activates or increases the frequency, rate or extent of estradiol secretion.
1 D2CJR2 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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