The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cystine-knot cytokines
".
FunFam 57: Interleukin 17E
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Interleukin-17E receptor binding GO:0030380
Interacting selectively and non-covalently with the interleukin-17E receptor.
|
2 | Q8VHC9 (/ISO) Q8VHH8 (/ISO) |
|
Interleukin-17E receptor binding GO:0030380
Interacting selectively and non-covalently with the interleukin-17E receptor.
|
1 | Q9H293 (/TAS) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
3 | D3ZLB1 (/IMP) Q8VHC9 (/IMP) Q8VHH8 (/IMP) |
|
Inflammatory response to antigenic stimulus GO:0002437
An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
|
2 | Q8VHC9 (/ISO) Q8VHH8 (/ISO) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
2 | Q8VHC9 (/ISO) Q8VHH8 (/ISO) |
|
Response to fungus GO:0009620
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Response to nematode GO:0009624
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Eosinophil differentiation GO:0030222
The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Interleukin-13 production GO:0032616
The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Interleukin-5 production GO:0032634
The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q8VHC9 (/IDA) Q8VHH8 (/IDA) |
|
Inflammatory response to antigenic stimulus GO:0002437
An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
|
1 | D3ZLB1 (/IMP) |
|
Interleukin-17-mediated signaling pathway GO:0097400
A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q9H293 (/TAS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q9H293 (/TAS) |
