The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cystine-knot cytokines
".
FunFam 5: Inhibin beta A chain
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 27 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
14 |
A4D1W7 (/IPI)
A4D1W7 (/IPI)
A4D1W7 (/IPI)
A4D1W7 (/IPI)
A4D1W7 (/IPI)
A4D1W7 (/IPI)
P07995 (/IPI)
P08476 (/IPI)
P08476 (/IPI)
P08476 (/IPI)
(4 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q04999 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
7 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P09529 (/TAS) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
6 | P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
6 | P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) |
|
Type II activin receptor binding GO:0070699
Interacting selectively and non-covalently with a type II activin receptor.
|
6 | P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) P08476 (/IPI) |
|
Inhibin binding GO:0034711
Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.
|
3 | Q04998 (/ISO) Q04998 (/ISO) Q04999 (/ISO) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
3 | Q04998 (/ISO) Q04998 (/ISO) Q04999 (/ISO) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | Q04998 (/IPI) Q04998 (/IPI) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Inhibin binding GO:0034711
Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.
|
2 | P17491 (/IPI) P18331 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P07995 (/ISS) Q9HBP0 (/ISS) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | P17491 (/IDA) P18331 (/IDA) |
|
Type II activin receptor binding GO:0070699
Interacting selectively and non-covalently with a type II activin receptor.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | P09529 (/TAS) |
|
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
|
1 | P55103 (/TAS) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
1 | Q9VQG9 (/IMP) |
|
Peptide hormone binding GO:0017046
Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
|
1 | P07995 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P09529 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q04999 (/ISO) |
|
Host cell surface receptor binding GO:0046789
Interacting selectively and non-covalently with a receptor on the host cell surface.
|
1 | P09529 (/TAS) |
|
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
|
1 | Q9VQG9 (/IDA) |
There are 159 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
27 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2GYF9 (/ISS)
D2H756 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P04088 (/ISS)
P07995 (/ISS)
P17491 (/ISS)
(17 more) |
|
Positive regulation of ovulation GO:0060279
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
|
24 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P03970 (/ISS)
P04088 (/ISS)
P07995 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
(14 more) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
Hemoglobin biosynthetic process GO:0042541
The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Progesterone secretion GO:0042701
The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Regulation of follicle-stimulating hormone secretion GO:0046880
Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
|
14 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q3SCJ9 (/ISS)
(4 more) |
|
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
|
14 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
Q04998 (/ISS)
(4 more) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
14 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q3SCJ9 (/ISS)
(4 more) |
|
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
|
13 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
Q04998 (/ISS)
(3 more) |
|
Eyelid development in camera-type eye GO:0061029
The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.
|
13 |
P03970 (/ISS)
P07995 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
P08476 (/ISS)
P18331 (/ISS)
P43032 (/ISS)
(3 more) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P09529 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q04999 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P09529 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P09529 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Negative regulation of insulin secretion GO:0046676
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P09529 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Positive regulation of follicle-stimulating hormone secretion GO:0046881
Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q04999 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Negative regulation of follicle-stimulating hormone secretion GO:0046882
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q04999 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Negative regulation of hepatocyte growth factor biosynthetic process GO:0048178
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q04999 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
|
8 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) Q04998 (/IDA) Q04998 (/IDA) |
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
8 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P09529 (/IDA) Q9VQG9 (/IDA) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
8 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) Q04998 (/IDA) Q04998 (/IDA) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
7 | P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P09529 (/NAS) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
7 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P09529 (/TAS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | P03970 (/ISS) P07995 (/ISS) P18331 (/ISS) P43032 (/ISS) P55102 (/ISS) Q6X2S4 (/ISS) Q6X2S4 (/ISS) |
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
6 | P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) |
|
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
|
6 | P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Cell surface receptor signaling pathway GO:0007166
A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
6 | P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
6 | P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862
Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Striatal medium spiny neuron differentiation GO:0021773
The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
6 | P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Positive regulation of cellular protein metabolic process GO:0032270
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Endodermal cell differentiation GO:0035987
The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Negative regulation of phosphorylation GO:0042326
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
|
6 | P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Hemoglobin biosynthetic process GO:0042541
The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Progesterone secretion GO:0042701
The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.
|
6 | P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) |
|
Negative regulation of interferon-gamma biosynthetic process GO:0045077
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Negative regulation of B cell differentiation GO:0045578
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Negative regulation of macrophage differentiation GO:0045650
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Regulation of follicle-stimulating hormone secretion GO:0046880
Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
6 | P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) |
|
Positive regulation of follicle-stimulating hormone secretion GO:0046881
Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
6 | P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) P08476 (/TAS) |
|
Negative regulation of follicle-stimulating hormone secretion GO:0046882
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
6 | P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) P08476 (/NAS) |
|
Negative regulation of hair follicle development GO:0051799
Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.
|
6 | A4D1W7 (/IDA) A4D1W7 (/IDA) A4D1W7 (/IDA) A4D1W7 (/IDA) A4D1W7 (/IDA) A4D1W7 (/IDA) |
|
Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
|
6 | P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) P08476 (/IGI) |
|
GABAergic neuron differentiation GO:0097154
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Extrinsic apoptotic signaling pathway GO:0097191
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | Q04998 (/ISO) Q04998 (/ISO) Q04999 (/ISO) |
|
Positive regulation of ovulation GO:0060279
Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
|
3 | Q04998 (/IMP) Q04998 (/IMP) Q04999 (/IMP) |
|
Cellular response to cholesterol GO:0071397
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
|
3 | Q04998 (/ISO) Q04998 (/ISO) Q04999 (/ISO) |
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Mesoderm formation GO:0001707
The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
|
2 | Q04998 (/IDA) Q04998 (/IDA) |
|
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862
Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Striatal medium spiny neuron differentiation GO:0021773
The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Fin regeneration GO:0031101
The regrowth of fin tissue following its loss or destruction.
|
2 | Q8QGE3 (/IMP) Q9W6T8 (/IMP) |
|
Positive regulation of cellular protein metabolic process GO:0032270
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Endodermal cell differentiation GO:0035987
The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Hemoglobin biosynthetic process GO:0042541
The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Progesterone secretion GO:0042701
The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q04998 (/IGI) Q04998 (/IGI) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Regulation of follicle-stimulating hormone secretion GO:0046880
Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Mesodermal cell differentiation GO:0048333
The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
|
2 | Q04998 (/IDA) Q04998 (/IDA) |
|
Negative regulation of hair follicle development GO:0051799
Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Eyelid development in camera-type eye GO:0061029
The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.
|
2 | Q04998 (/IGI) Q04998 (/IGI) |
|
Cellular response to follicle-stimulating hormone stimulus GO:0071372
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Cellular response to cholesterol GO:0071397
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
|
2 | P17491 (/IDA) P18331 (/IDA) |
|
GABAergic neuron differentiation GO:0097154
The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Extrinsic apoptotic signaling pathway GO:0097191
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Cardiac muscle myoblast proliferation GO:0110021
The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
|
2 | Q8QGE3 (/IMP) Q9W6T8 (/IMP) |
|
Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Embryonic axis specification GO:0000578
The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.
|
1 | Q91350 (/IMP) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
1 | Q04999 (/TAS) |
|
Positive regulation of neuroblast proliferation GO:0002052
Any process that activates or increases the rate of neuroblast proliferation.
|
1 | Q9VQG9 (/IGI) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | P17491 (/IEP) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q9VQG9 (/IMP) |
|
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
1 | P27092 (/NAS) |
|
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | Q9VQG9 (/IMP) |
|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
1 | P17491 (/IEP) |
|
Female gonad development GO:0008585
The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
|
1 | P17491 (/IEP) |
|
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
|
1 | Q04999 (/IEP) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
1 | P09529 (/IEP) |
|
Negative regulation of autophagy GO:0010507
Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q9VQG9 (/IMP) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | P17491 (/IEP) |
|
Response to insecticide GO:0017085
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
|
1 | P17491 (/IEP) |
|
Pituitary gland development GO:0021983
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
|
1 | P17491 (/IEP) |
|
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
1 | P09529 (/NAS) |
|
Cellular response to nutrient levels GO:0031669
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
1 | Q9VQG9 (/IMP) |
|
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | Q04999 (/IEP) |
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q9VQG9 (/IGI) |
|
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q9VQG9 (/IMP) |
|
Response to gonadotropin GO:0034698
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to leptin stimulus GO:0044320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.
|
1 | Q04999 (/IEP) |
|
Regulation of imaginal disc-derived wing size GO:0044719
Any process that modulates the size of an imaginal disc-derived wing.
|
1 | Q9VQG9 (/IMP) |
|
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
|
1 | Q04999 (/IEP) |
|
R8 cell fate specification GO:0045464
The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
1 | Q9VQG9 (/IMP) |
|
Positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743
Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
|
1 | Q91350 (/IDA) |
|
Negative regulation of insulin secretion GO:0046676
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
|
1 | Q04999 (/IMP) |
|
Positive regulation of follicle-stimulating hormone secretion GO:0046881
Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | P09529 (/IPI) |
|
Positive regulation of follicle-stimulating hormone secretion GO:0046881
Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | Q04999 (/ISO) |
|
Negative regulation of follicle-stimulating hormone secretion GO:0046882
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | P09529 (/IPI) |
|
Negative regulation of follicle-stimulating hormone secretion GO:0046882
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
|
1 | Q04999 (/ISO) |
|
Negative regulation of hepatocyte growth factor biosynthetic process GO:0048178
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
|
1 | P09529 (/IDA) |
|
Negative regulation of hepatocyte growth factor biosynthetic process GO:0048178
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
|
1 | Q04999 (/ISO) |
|
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
1 | Q04999 (/IGI) |
|
Regulation of synapse structure or activity GO:0050803
Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
|
1 | Q9VQG9 (/IMP) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
1 | Q9VQG9 (/IMP) |
|
Cellular response to interleukin-1 GO:0071347
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
|
1 | P17491 (/IEP) |
|
Cellular response to follicle-stimulating hormone stimulus GO:0071372
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
|
1 | P18331 (/IDA) |
|
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | P17491 (/IEP) |
|
Seminiferous tubule development GO:0072520
The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.
|
1 | P17491 (/IEP) |
|
Cellular response to thyroid hormone stimulus GO:0097067
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
|
1 | P17491 (/IEP) |
|
Nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry GO:1900164
A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.
|
1 | P27093 (/TAS) |
|
Cellular response to Thyroglobulin triiodothyronine GO:1904017
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.
|
1 | P17491 (/IEP) |
|
Reproductive senescence GO:1990636
A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones.
|
1 | P17491 (/IEP) |
|
Positive regulation of apoptotic signaling pathway GO:2001235
Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
|
1 | Q04999 (/IGI) |
There are 21 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
17 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(7 more) |
|
Activin A complex GO:0043509
A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
|
16 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P18331 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
(6 more) |
|
Inhibin A complex GO:0043512
Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.
|
15 |
D2GYF9 (/ISS)
E2QW13 (/ISS)
E2QW13 (/ISS)
P03970 (/ISS)
P07995 (/ISS)
P27092 (/ISS)
P43032 (/ISS)
P55102 (/ISS)
Q04998 (/ISS)
Q04998 (/ISS)
(5 more) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
11 |
P08476 (/TAS)
P08476 (/TAS)
P08476 (/TAS)
P08476 (/TAS)
P08476 (/TAS)
P08476 (/TAS)
P09529 (/TAS)
P55103 (/TAS)
Q04998 (/TAS)
Q04998 (/TAS)
(1 more) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
11 |
A5JNM7 (/ISS)
B6DT33 (/ISS)
D2H756 (/ISS)
P04088 (/ISS)
P17491 (/ISS)
P27093 (/ISS)
P42917 (/ISS)
Q04999 (/ISS)
Q589C7 (/ISS)
Q6X2S3 (/ISS)
(1 more) |
|
Inhibin A complex GO:0043512
Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.
|
7 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P18331 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Activin A complex GO:0043509
A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
|
6 | P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) P08476 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
4 | P09529 (/IDA) Q04998 (/IDA) Q04998 (/IDA) Q04999 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | Q04998 (/HDA) Q04998 (/HDA) Q04999 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | Q04998 (/ISO) Q04998 (/ISO) Q04999 (/ISO) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P17491 (/IDA) P18331 (/IDA) |
|
Activin A complex GO:0043509
A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Inhibin A complex GO:0043512
Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.
|
2 | Q04998 (/ISO) Q04998 (/ISO) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9VQG9 (/IC) |
|
Inhibin B complex GO:0043513
Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.
|
1 | P17491 (/IDA) |
|
Inhibin B complex GO:0043513
Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.
|
1 | Q04999 (/ISO) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q04999 (/ISO) |
|
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
|
1 | P58166 (/HDA) |
|
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
|
1 | Q04999 (/IDA) |
