The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cystine-knot cytokines
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 41: Platelet-derived growth factor beta polypeptide b

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
4 A0A088AWM4 (/IMP) A0A2R8PYF1 (/IMP) F1QS30 (/IMP) Q1LUW1 (/IMP)
Regulation of DNA replication GO:0006275
Any process that modulates the frequency, rate or extent of DNA replication.
4 A0A088AWM4 (/IDA) A0A2R8PYF1 (/IDA) F1QS30 (/IDA) Q1LUW1 (/IDA)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
4 A0A088AWM4 (/IEP) A0A2R8PYF1 (/IEP) F1QS30 (/IEP) Q1LUW1 (/IEP)
Blood vessel morphogenesis GO:0048514
The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
4 A0A088AWM4 (/IMP) A0A2R8PYF1 (/IMP) F1QS30 (/IMP) Q1LUW1 (/IMP)
Epicardial cell to mesenchymal cell transition GO:0003347
A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium.
1 E7FBB3 (/IDA)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
1 E7FBB3 (/IMP)
Platelet-derived growth factor receptor-beta signaling pathway GO:0035791
A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 E7FBB3 (/IMP)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
1 E7FBB3 (/IMP)
Positive regulation of epithelial cell proliferation GO:0050679
Any process that activates or increases the rate or extent of epithelial cell proliferation.
1 E7FBB3 (/IMP)
Positive regulation of stress fiber assembly GO:0051496
Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
1 E7FBB3 (/IDA)
Angiogenesis involved in coronary vascular morphogenesis GO:0060978
Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.
1 E7FBB3 (/IMP)
Negative regulation of adherens junction organization GO:1903392
Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization.
1 E7FBB3 (/IDA)
Regulation of Rho-dependent protein serine/threonine kinase activity GO:2000298
Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
1 E7FBB3 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
CATH-Gene3D is a Global Biodata Core Resource Learn more...