The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cystine-knot cytokines
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23: Platelet-derived growth factor subunit B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 27 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
6 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
2 P31240 (/ISO) P31240 (/ISO)
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
2 P01127 (/IDA) P01127 (/IDA)
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
2 P01127 (/IPI) P01127 (/IPI)
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
2 P31240 (/ISO) P31240 (/ISO)
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
2 P01127 (/NAS) P01127 (/NAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P01127 (/IPI) P01127 (/IPI)
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2 P01127 (/IDA) P01127 (/IDA)
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
2 P31240 (/ISO) P31240 (/ISO)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
2 P01127 (/IDA) P01127 (/IDA)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
2 P31240 (/ISO) P31240 (/ISO)
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
2 P01127 (/IDA) P01127 (/IDA)
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
2 P31240 (/ISO) P31240 (/ISO)
Chemoattractant activity GO:0042056
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.
2 P01127 (/IDA) P01127 (/IDA)
Chemoattractant activity GO:0042056
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.
2 P31240 (/ISO) P31240 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P01127 (/IPI) P01127 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P31240 (/ISO) P31240 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 P01127 (/IDA) P01127 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 P31240 (/ISO) P31240 (/ISO)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 P01127 (/IPI) P01127 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 P31240 (/ISO) P31240 (/ISO)
Platelet-derived growth factor binding GO:0048407
Interacting selectively and non-covalently with platelet-derived growth factor.
2 P01127 (/IPI) P01127 (/IPI)
Platelet-derived growth factor binding GO:0048407
Interacting selectively and non-covalently with platelet-derived growth factor.
2 P31240 (/ISO) P31240 (/ISO)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q05028 (/IMP)

There are 213 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to mycophenolic acid GO:0071506
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
8 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
7 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Monocyte chemotaxis GO:0002548
The movement of a monocyte in response to an external stimulus.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of glomerular filtration GO:0003104
Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
7 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
7 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Negative regulation of phosphatidylinositol biosynthetic process GO:0010512
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Negative regulation of platelet activation GO:0010544
Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of protein autophosphorylation GO:0031954
Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Activation of protein kinase B activity GO:0032148
Any process that initiates the activity of the inactive enzyme protein kinase B.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway GO:0035793
Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Paracrine signaling GO:0038001
The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.
7 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045737
Any process that activates or increases the frequency, rate or extent of CDK activity.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of mitotic nuclear division GO:0045840
Any process that activates or increases the frequency, rate or extent of mitosis.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of fibroblast proliferation GO:0048146
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of glomerular mesangial cell proliferation GO:0072126
Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Metanephric glomerular mesangial cell development GO:0072255
The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.
7 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of hyaluronan biosynthetic process GO:1900127
Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of reactive oxygen species metabolic process GO:2000379
Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of DNA biosynthetic process GO:2000573
Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of MAP kinase activity GO:0043406
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
6 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
6 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Platelet-derived growth factor receptor signaling pathway GO:0048008
The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.
6 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
5 P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
4 P12919 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
4 P12919 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of vascular smooth muscle cell proliferation GO:1904707
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
4 P12919 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of metanephric mesenchymal cell migration GO:2000591
Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.
4 P12919 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
3 P31240 (/IMP) P31240 (/IMP) Q05028 (/IMP)
Positive regulation of MAP kinase activity GO:0043406
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
3 P01127 (/IDA) P01127 (/IDA) Q05028 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
3 P01127 (/IDA) P01127 (/IDA) Q05028 (/IDA)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
3 P31240 (/IMP) P31240 (/IMP) Q05028 (/IMP)
Positive regulation of metanephric mesenchymal cell migration GO:2000591
Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.
3 P01127 (/IDA) P01127 (/IDA) Q05028 (/IDA)
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
2 P01127 (/TAS) P01127 (/TAS)
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
2 P31240 (/IEP) P31240 (/IEP)
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
2 P31240 (/IMP) P31240 (/IMP)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
2 P31240 (/IGI) P31240 (/IGI)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
2 P31240 (/ISO) P31240 (/ISO)
Monocyte chemotaxis GO:0002548
The movement of a monocyte in response to an external stimulus.
2 P01127 (/IDA) P01127 (/IDA)
Monocyte chemotaxis GO:0002548
The movement of a monocyte in response to an external stimulus.
2 P31240 (/ISO) P31240 (/ISO)
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2 P01127 (/TAS) P01127 (/TAS)
Positive regulation of glomerular filtration GO:0003104
Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
2 P31240 (/IMP) P31240 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P01127 (/IDA) P01127 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
2 P31240 (/ISO) P31240 (/ISO)
Substrate-dependent cell migration GO:0006929
The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.
2 P31240 (/IDA) P31240 (/IDA)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
2 P31240 (/IMP) P31240 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
2 P31240 (/IMP) P31240 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 P31240 (/ISO) P31240 (/ISO)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
2 P01127 (/IDA) P01127 (/IDA)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
2 P31240 (/ISO) P31240 (/ISO)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
2 P01127 (/NAS) P01127 (/NAS)
Negative regulation of phosphatidylinositol biosynthetic process GO:0010512
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
2 P01127 (/IDA) P01127 (/IDA)
Negative regulation of phosphatidylinositol biosynthetic process GO:0010512
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of platelet activation GO:0010544
Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
2 P01127 (/IDA) P01127 (/IDA)
Negative regulation of platelet activation GO:0010544
Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P01127 (/IDA) P01127 (/IDA)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
2 P31240 (/IGI) P31240 (/IGI)
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
2 P31240 (/ISO) P31240 (/ISO)
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
2 P31240 (/IMP) P31240 (/IMP)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
2 P01127 (/IDA) P01127 (/IDA)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
2 P31240 (/ISO) P31240 (/ISO)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
2 P01127 (/IDA) P01127 (/IDA)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
2 P31240 (/ISO) P31240 (/ISO)
Glial cell development GO:0021782
The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
2 P31240 (/IMP) P31240 (/IMP)
Cell projection assembly GO:0030031
Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
2 P31240 (/IDA) P31240 (/IDA)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2 P31240 (/IDA) P31240 (/IDA)
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2 P31240 (/IGI) P31240 (/IGI)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
2 P01127 (/TAS) P01127 (/TAS)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
2 P31240 (/IGI) P31240 (/IGI)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
2 P31240 (/IGI) P31240 (/IGI)
Positive regulation of protein autophosphorylation GO:0031954
Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of protein autophosphorylation GO:0031954
Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
2 P01127 (/IDA) P01127 (/IDA)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
2 P31240 (/ISO) P31240 (/ISO)
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
2 P01127 (/IDA) P01127 (/IDA)
Activation of protein kinase activity GO:0032147
Any process that initiates the activity of an inactive protein kinase.
2 P31240 (/ISO) P31240 (/ISO)
Activation of protein kinase B activity GO:0032148
Any process that initiates the activity of the inactive enzyme protein kinase B.
2 P01127 (/IDA) P01127 (/IDA)
Activation of protein kinase B activity GO:0032148
Any process that initiates the activity of the inactive enzyme protein kinase B.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
2 P31240 (/ISO) P31240 (/ISO)
Interleukin-18-mediated signaling pathway GO:0035655
A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P01127 (/IDA) P01127 (/IDA)
Interleukin-18-mediated signaling pathway GO:0035655
A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway GO:0035793
Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway GO:0035793
Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.
2 P31240 (/ISO) P31240 (/ISO)
Paracrine signaling GO:0038001
The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.
2 P31240 (/IMP) P31240 (/IMP)
Positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033
A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.
2 P31240 (/TAS) P31240 (/TAS)
Eye photoreceptor cell development GO:0042462
Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.
2 P31240 (/IMP) P31240 (/IMP)
Positive regulation of MAP kinase activity GO:0043406
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
2 P01127 (/IMP) P01127 (/IMP)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045737
Any process that activates or increases the frequency, rate or extent of CDK activity.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045737
Any process that activates or increases the frequency, rate or extent of CDK activity.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743
Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
2 P31240 (/IDA) P31240 (/IDA)
Positive regulation of mitotic nuclear division GO:0045840
Any process that activates or increases the frequency, rate or extent of mitosis.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of mitotic nuclear division GO:0045840
Any process that activates or increases the frequency, rate or extent of mitosis.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 P01127 (/IDA) P01127 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
2 P31240 (/TAS) P31240 (/TAS)
Positive regulation of mitotic cell cycle, embryonic GO:0045977
Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle.
2 P31240 (/IGI) P31240 (/IGI)
Platelet-derived growth factor receptor signaling pathway GO:0048008
The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.
2 P01127 (/IDA) P01127 (/IDA)
Platelet-derived growth factor receptor signaling pathway GO:0048008
The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of fibroblast proliferation GO:0048146
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of fibroblast proliferation GO:0048146
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
2 P31240 (/ISO) P31240 (/ISO)
Blood vessel morphogenesis GO:0048514
The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
2 P31240 (/IDA) P31240 (/IDA)
Blood vessel morphogenesis GO:0048514
The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
2 P31240 (/IGI) P31240 (/IGI)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
2 P31240 (/ISO) P31240 (/ISO)
Regulation of peptidyl-tyrosine phosphorylation GO:0050730
Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
2 P31240 (/IDA) P31240 (/IDA)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of chemotaxis GO:0050921
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
2 P01127 (/TAS) P01127 (/TAS)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
2 P31240 (/IMP) P31240 (/IMP)
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
2 P01127 (/IDA) P01127 (/IDA)
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
2 P31240 (/ISO) P31240 (/ISO)
Branching involved in salivary gland morphogenesis GO:0060445
The process in which the branching structure of the salivary gland is generated and organized.
2 P31240 (/IMP) P31240 (/IMP)
Epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664
The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.
2 P31240 (/IMP) P31240 (/IMP)
Cardiac vascular smooth muscle cell differentiation GO:0060947
The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
2 P31240 (/TAS) P31240 (/TAS)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
2 P31240 (/ISO) P31240 (/ISO)
Retina vasculature development in camera-type eye GO:0061298
The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.
2 P31240 (/IMP) P31240 (/IMP)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
2 P31240 (/ISO) P31240 (/ISO)
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
2 P01127 (/IMP) P01127 (/IMP)
Protein kinase C signaling GO:0070528
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
2 P31240 (/ISO) P31240 (/ISO)
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
2 P01127 (/IDA) P01127 (/IDA)
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
2 P31240 (/ISO) P31240 (/ISO)
Cellular response to mycophenolic acid GO:0071506
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of glomerular mesangial cell proliferation GO:0072126
Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of glomerular mesangial cell proliferation GO:0072126
Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.
2 P31240 (/ISO) P31240 (/ISO)
Metanephric glomerular mesangial cell development GO:0072255
The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.
2 P31240 (/IMP) P31240 (/IMP)
Metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262
The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.
2 P31240 (/IMP) P31240 (/IMP)
Metanephric glomerular endothelium development GO:0072264
The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.
2 P31240 (/IEP) P31240 (/IEP)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
2 P01127 (/IMP) P01127 (/IMP)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of calcium ion import GO:0090280
Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of blood vessel diameter GO:0097756
Any process that decreases the diameter of blood vessels.
2 P31240 (/TAS) P31240 (/TAS)
Positive regulation of hyaluronan biosynthetic process GO:1900127
Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of hyaluronan biosynthetic process GO:1900127
Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of pri-miRNA transcription by RNA polymerase II GO:1902894
Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
2 P01127 (/IDA) P01127 (/IDA)
Negative regulation of pri-miRNA transcription by RNA polymerase II GO:1902894
Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895
Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895
Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of vascular smooth muscle cell proliferation GO:1904707
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of vascular smooth muscle cell proliferation GO:1904707
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of vascular associated smooth muscle cell migration GO:1904754
Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of vascular associated smooth muscle cell migration GO:1904754
Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of hepatic stellate cell proliferation GO:1904899
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.
2 P31240 (/ISO) P31240 (/ISO)
Negative regulation of vascular smooth muscle cell differentiation GO:1905064
Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.
2 P01127 (/IDA) P01127 (/IDA)
Negative regulation of vascular smooth muscle cell differentiation GO:1905064
Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of vascular smooth muscle cell dedifferentiation GO:1905176
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of vascular smooth muscle cell dedifferentiation GO:1905176
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of reactive oxygen species metabolic process GO:2000379
Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of reactive oxygen species metabolic process GO:2000379
Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of hepatic stellate cell activation GO:2000491
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of DNA biosynthetic process GO:2000573
Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
2 P01127 (/IDA) P01127 (/IDA)
Positive regulation of DNA biosynthetic process GO:2000573
Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
2 P31240 (/ISO) P31240 (/ISO)
Positive regulation of metanephric mesenchymal cell migration GO:2000591
Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.
2 P31240 (/ISO) P31240 (/ISO)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 Q05028 (/IEP)
DNA replication GO:0006260
The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
1 Q05028 (/IEP)
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
1 Q05028 (/IEP)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 Q05028 (/IEP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 Q05028 (/IEP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 B1H0W5 (/IMP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 P12919 (/ISS)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 Q05028 (/IEP)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 Q05028 (/IEP)
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
1 Q05028 (/IMP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 Q05028 (/IEP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
1 Q05028 (/IEP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q05028 (/IEP)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 Q05028 (/IEP)
Response to human chorionic gonadotropin GO:0044752
Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
1 Q05028 (/IEP)
Platelet-derived growth factor receptor signaling pathway GO:0048008
The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.
1 Q05028 (/IMP)
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
1 Q05028 (/IEP)
Cellular response to mechanical stimulus GO:0071260
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
1 Q05028 (/IEP)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 B1H0W5 (/IEP)
Cellular response to mycophenolic acid GO:0071506
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
1 Q05028 (/IDA)
Cellular response to angiotensin GO:1904385
\Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.\
1 Q05028 (/IEP)
Positive regulation of hepatic stellate cell proliferation GO:1904899
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.
1 Q05028 (/IMP)
Positive regulation of hepatic stellate cell activation GO:2000491
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.
1 Q05028 (/IMP)

There are 22 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
8 P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
7 P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
2 P01127 (/TAS) P01127 (/TAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P01127 (/NAS) P01127 (/NAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P01127 (/TAS) P01127 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P31240 (/ISO) P31240 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P31240 (/ISO) P31240 (/ISO)
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
2 P01127 (/TAS) P01127 (/TAS)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
2 P01127 (/TAS) P01127 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P01127 (/IDA) P01127 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P31240 (/ISO) P31240 (/ISO)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
2 P31240 (/ISO) P31240 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
2 P31240 (/ISO) P31240 (/ISO)
Platelet alpha granule lumen GO:0031093
The volume enclosed by the membrane of the platelet alpha granule.
2 P01127 (/TAS) P01127 (/TAS)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 P31240 (/ISO) P31240 (/ISO)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
2 P01127 (/HDA) P01127 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q05028 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q05028 (/IDA)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q05028 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q05028 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q05028 (/IDA)
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