The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CD59
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Ly6/PLAUR domain-containing protein 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 Q66IA6 (/IPI) Q86Y78 (/IPI) Q86Y78 (/IPI) Q86Y78 (/IPI) Q86Y78 (/IPI) Q86Y78 (/IPI) Q86Y78 (/IPI)
Acetylcholine receptor inhibitor activity GO:0030550
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased.
7 D3ZTT2 (/IDA) Q86Y78 (/IDA) Q86Y78 (/IDA) Q86Y78 (/IDA) Q86Y78 (/IDA) Q86Y78 (/IDA) Q86Y78 (/IDA)
Acetylcholine receptor regulator activity GO:0030548
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
1 Q8NI32 (/IDA)
Acetylcholine receptor regulator activity GO:0030548
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
1 Q8BPP5 (/IMP)
Acetylcholine receptor regulator activity GO:0030548
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
1 Q9D7F2 (/ISO)
Acetylcholine receptor inhibitor activity GO:0030550
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased.
1 Q8BPP5 (/ISO)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Spemann organizer formation GO:0060061
Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.
1 Q66IA6 (/IGI)
Spemann organizer formation GO:0060061
Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.
1 Q66IA6 (/IMP)
Regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation GO:0060827
Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern.
1 Q66IA6 (/IMP)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q66IA6 (/IGI)
Regulation of Wnt signaling pathway involved in dorsal/ventral axis specification GO:2000053
Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
1 Q66IA6 (/IGI)
Regulation of Wnt signaling pathway involved in dorsal/ventral axis specification GO:2000053
Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
1 Q66IA6 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q8NI32 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q66IA6 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8NI32 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 D3ZTT2 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q8BPP5 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 D3ZTT2 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q8BPP5 (/ISO)
Anchored component of plasma membrane GO:0046658
The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
1 Q66IA6 (/IDA)
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