The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CD59
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 26: Secreted Ly-6/uPAR domain-containing protein 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acetylcholine receptor regulator activity GO:0030548
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
5 P0DP59 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS)
Acetylcholine receptor binding GO:0033130
Interacting selectively and non-covalently with an acetylcholine receptor.
5 P0DP59 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS)
Acetylcholine receptor regulator activity GO:0030548
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
3 P0DP57 (/IDA) P0DP57 (/IDA) P0DP57 (/IDA)
Acetylcholine receptor binding GO:0033130
Interacting selectively and non-covalently with an acetylcholine receptor.
3 P0DP57 (/IDA) P0DP57 (/IDA) P0DP57 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acetylcholine receptor signaling pathway GO:0095500
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
5 P0DP59 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS)
Regulation of neurotransmitter receptor activity GO:0099601
Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
5 P0DP59 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS)
Acetylcholine receptor signaling pathway GO:0095500
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
3 P0DP57 (/IDA) P0DP57 (/IDA) P0DP57 (/IDA)
Regulation of neurotransmitter receptor activity GO:0099601
Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
3 P0DP57 (/IDA) P0DP57 (/IDA) P0DP57 (/IDA)
Keratinocyte proliferation GO:0043616
The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.
1 P0DP59 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
5 P0DP59 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS) P0DP61 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
3 P0DP57 (/IDA) P0DP57 (/IDA) P0DP57 (/IDA)
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