The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ankyrin repeat-containing domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Poly [ADP-ribose] polymerase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NAD+ ADP-ribosyltransferase activity GO:0003950
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
5 O95271 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9VBP3 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 O95271 (/IPI) Q9H2K2 (/IPI) Q9H2K2 (/IPI) Q9H2K2 (/IPI) Q9VBP3 (/IPI)
NAD+ ADP-ribosyltransferase activity GO:0003950
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
4 O95271 (/TAS) Q9H2K2 (/TAS) Q9H2K2 (/TAS) Q9H2K2 (/TAS)
Protein ADP-ribosylase activity GO:1990404
The transfer, from NAD, of ADP-ribose to a protein amino acid residue.
4 O95271 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
3 Q9H2K2 (/IPI) Q9H2K2 (/IPI) Q9H2K2 (/IPI)
NAD+ ADP-ribosyltransferase activity GO:0003950
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
NAD+ ADP-ribosyltransferase activity GO:0003950
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
2 Q3UES3 (/ISS) Q6PFX9 (/ISS)
Protein ADP-ribosylase activity GO:1990404
The transfer, from NAD, of ADP-ribose to a protein amino acid residue.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Protein ADP-ribosylase activity GO:1990404
The transfer, from NAD, of ADP-ribose to a protein amino acid residue.
2 Q3UES3 (/ISS) Q6PFX9 (/ISS)
NAD+ ADP-ribosyltransferase activity GO:0003950
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
1 Q9VBP3 (/IGI)
NAD+ ADP-ribosyltransferase activity GO:0003950
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
1 Q9VBP3 (/IMP)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 O95271 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q6PFX9 (/ISO)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q3UES3 (/ISO)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
1 O95271 (/IPI)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
1 Q6PFX9 (/ISO)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 D3ZRP5 (/IPI)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q3UES3 (/ISO)
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
1 Q9VBP3 (/IPI)

There are 52 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein ADP-ribosylation GO:0006471
The transfer, from NAD, of ADP-ribose to protein amino acids.
5 O95271 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9VBP3 (/IDA)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
5 O95271 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP) Q9VBP3 (/IMP)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
4 O95271 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Protein localization to chromosome, telomeric region GO:0070198
Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.
4 O95271 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP)
Protein poly-ADP-ribosylation GO:0070212
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
4 O95271 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Protein auto-ADP-ribosylation GO:0070213
The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
4 O95271 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
4 O95271 (/TAS) Q9H2K2 (/TAS) Q9H2K2 (/TAS) Q9H2K2 (/TAS)
Positive regulation of telomere capping GO:1904355
Any process that activates or increases the frequency, rate or extent of telomere capping.
4 O95271 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Positive regulation of telomere capping GO:1904355
Any process that activates or increases the frequency, rate or extent of telomere capping.
4 O95271 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP)
Negative regulation of telomere maintenance via telomere lengthening GO:1904357
Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.
4 O95271 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP) Q9H2K2 (/IMP)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
3 Q9H2K2 (/IC) Q9H2K2 (/IC) Q9H2K2 (/IC)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
3 A0A0R4IYN3 (/IMP) A0A2R8QG67 (/IMP) A3KGU1 (/IMP)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
2 Q3UES3 (/ISS) Q6PFX9 (/ISS)
Protein ADP-ribosylation GO:0006471
The transfer, from NAD, of ADP-ribose to protein amino acids.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Protein localization to chromosome, telomeric region GO:0070198
Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Protein poly-ADP-ribosylation GO:0070212
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
2 O95271 (/IMP) Q9VBP3 (/IMP)
Protein poly-ADP-ribosylation GO:0070212
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Protein poly-ADP-ribosylation GO:0070212
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
2 Q3UES3 (/ISS) Q6PFX9 (/ISS)
Protein auto-ADP-ribosylation GO:0070213
The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Protein auto-ADP-ribosylation GO:0070213
The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
2 Q3UES3 (/ISS) Q6PFX9 (/ISS)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
2 Q3UES3 (/ISS) Q6PFX9 (/ISS)
Positive regulation of telomere capping GO:1904355
Any process that activates or increases the frequency, rate or extent of telomere capping.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Negative regulation of telomere maintenance via telomere lengthening GO:1904357
Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.
2 Q3UES3 (/ISO) Q6PFX9 (/ISO)
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
1 Q3UES3 (/ISS)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
1 O95271 (/TAS)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
1 O95271 (/IDA)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
1 Q6PFX9 (/ISO)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 O95271 (/IDA)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 Q6PFX9 (/ISO)
Cellular response to nutrient GO:0031670
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 D3Z8Q6 (/IEP)
Regulation of telomere maintenance via telomerase GO:0032210
Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
1 O95271 (/IC)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
1 O95271 (/IDA)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
1 O95271 (/IMP)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
1 Q6PFX9 (/ISO)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 Q3UES3 (/IMP)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
1 Q3UES3 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 O95271 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q6PFX9 (/ISO)
Spindle assembly GO:0051225
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
1 O95271 (/TAS)
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
1 O95271 (/IDA)
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
1 Q6PFX9 (/ISO)
Protein poly-ADP-ribosylation GO:0070212
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
1 Q9VBP3 (/IGI)
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q9VBP3 (/IDA)
Regulation of proteasome assembly GO:0090364
Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.
1 Q9VBP3 (/IDA)
Negative regulation of telomeric DNA binding GO:1904743
Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.
1 O95271 (/IDA)
Negative regulation of telomeric DNA binding GO:1904743
Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.
1 O95271 (/IMP)
Negative regulation of telomeric DNA binding GO:1904743
Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.
1 Q6PFX9 (/ISO)
Negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric GO:1904908
Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
1 O95271 (/IMP)
Negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric GO:1904908
Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
1 Q6PFX9 (/ISO)
Positive regulation of ubiquitin-dependent protein catabolic process GO:2000060
Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process.
1 Q9VBP3 (/IMP)

There are 32 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 O95271 (/TAS) Q9H2K2 (/TAS) Q9H2K2 (/TAS) Q9H2K2 (/TAS)
Pericentriolar material GO:0000242
A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.
3 Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
3 Q9H2K2 (/IC) Q9H2K2 (/IC) Q9H2K2 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
3 Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 Q9H2K2 (/IDA) Q9H2K2 (/IDA) Q9H2K2 (/IDA)
Pericentriolar material GO:0000242
A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.
1 Q3UES3 (/ISO)
Pericentriolar material GO:0000242
A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.
1 O95271 (/TAS)
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
1 O95271 (/IDA)
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
1 Q6PFX9 (/ISO)
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
1 O95271 (/IDA)
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
1 Q6PFX9 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q3UES3 (/ISO)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
1 Q3UES3 (/ISO)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
1 O95271 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O95271 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q6PFX9 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q3UES3 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 O95271 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q6PFX9 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q6PFX9 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q6PFX9 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 O95271 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 Q6PFX9 (/ISO)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 O95271 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 Q6PFX9 (/ISO)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 O95271 (/TAS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q3UES3 (/ISO)
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 O95271 (/IDA)
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 Q6PFX9 (/ISO)
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 Q6PFX9 (/ISS)
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