The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Tetratricopeptide repeat domain
".
FunFam 198: E3 ubiquitin-protein ligase CHIP isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 48 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
14 |
D4A4T0 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(4 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
13 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(3 more) |
|
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
13 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(3 more) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
13 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(3 more) |
|
Ubiquitin-ubiquitin ligase activity GO:0034450
Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
|
13 |
Q5ZHY5 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(3 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
13 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(3 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
13 |
Q5ZHY5 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(3 more) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
13 |
D4A4T0 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(3 more) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
13 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(3 more) |
|
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
12 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(2 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
12 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(2 more) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
12 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(2 more) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
12 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(2 more) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
12 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(2 more) |
|
TPR domain binding GO:0030911
Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
12 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(2 more) |
|
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
12 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(2 more) |
|
Tau protein binding GO:0048156
Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
|
12 |
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
Q9UNE7 (/NAS)
(2 more) |
|
Misfolded protein binding GO:0051787
Interacting selectively and non-covalently with a misfolded protein.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
12 |
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
(2 more) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
12 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(2 more) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
12 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(2 more) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
2 | Q5ZHY5 (/ISS) Q9WUD1 (/ISS) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
TPR domain binding GO:0030911
Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
1 | Q9WUD1 (/ISO) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | Q9WUD1 (/ISO) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q9WUD1 (/ISO) |
|
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
|
1 | Q9WUD1 (/ISO) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
1 | Q9WUD1 (/ISO) |
|
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
|
1 | Q9WUD1 (/TAS) |
|
TPR domain binding GO:0030911
Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.
|
1 | Q9WUD1 (/ISO) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
1 | Q9WUD1 (/ISO) |
|
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
|
1 | Q9WUD1 (/TAS) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q9WUD1 (/ISO) |
|
Ubiquitin-ubiquitin ligase activity GO:0034450
Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
|
1 | Q9WUD1 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9WUD1 (/ISO) |
|
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
|
1 | Q9WUD1 (/ISO) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
1 | Q9WUD1 (/ISO) |
|
Misfolded protein binding GO:0051787
Interacting selectively and non-covalently with a misfolded protein.
|
1 | Q9WUD1 (/ISO) |
|
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
|
1 | Q9WUD1 (/ISO) |
|
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
|
1 | Q9WUD1 (/ISO) |
There are 69 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
14 |
Q5ZHY5 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(4 more) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
13 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(3 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
13 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(3 more) |
|
Positive regulation of protein ubiquitination GO:0031398
Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
13 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(3 more) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
13 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(3 more) |
|
Protein maturation GO:0051604
Any process leading to the attainment of the full functional capacity of a protein.
|
13 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(3 more) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
12 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(2 more) |
|
Response to ischemia GO:0002931
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
|
12 |
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(2 more) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
12 |
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
Q9UNE7 (/IGI)
(2 more) |
|
Protein quality control for misfolded or incompletely synthesized proteins GO:0006515
The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
12 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(2 more) |
|
Ubiquitin-dependent ERAD pathway GO:0030433
The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
|
12 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(2 more) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
12 |
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
Q9UNE7 (/IMP)
(2 more) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
12 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(2 more) |
|
Ubiquitin-dependent SMAD protein catabolic process GO:0030579
The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Regulation of glucocorticoid metabolic process GO:0031943
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
12 |
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(2 more) |
|
ERBB2 signaling pathway GO:0038128
A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.
|
12 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(2 more) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
12 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(2 more) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Protein K63-linked ubiquitination GO:0070534
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Cellular response to misfolded protein GO:0071218
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
12 |
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(2 more) |
|
Positive regulation of chaperone-mediated protein complex assembly GO:0090035
Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
3 | Q5ZHY5 (/ISS) Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
3 | Q5ZHY5 (/ISS) Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
Ubiquitin-dependent SMAD protein catabolic process GO:0030579
The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
Positive regulation of protein ubiquitination GO:0031398
Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
Regulation of glucocorticoid metabolic process GO:0031943
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
2 | Q7ZTZ6 (/ISS) Q9WUD1 (/ISS) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
1 | Q9WUD1 (/ISO) |
|
Response to ischemia GO:0002931
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
|
1 | D4A4T0 (/IDA) |
|
Response to ischemia GO:0002931
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
|
1 | Q9WUD1 (/ISO) |
|
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
|
1 | Q9WUD1 (/TAS) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
1 | Q9WUD1 (/ISO) |
|
Protein quality control for misfolded or incompletely synthesized proteins GO:0006515
The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
|
1 | Q9WUD1 (/IMP) |
|
Protein quality control for misfolded or incompletely synthesized proteins GO:0006515
The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
|
1 | Q9WUD1 (/ISO) |
|
Protein quality control for misfolded or incompletely synthesized proteins GO:0006515
The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
|
1 | Q5ZHY5 (/ISS) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | Q9WUD1 (/ISO) |
|
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
|
1 | Q9WUD1 (/TAS) |
|
Ubiquitin-dependent ERAD pathway GO:0030433
The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
|
1 | Q9WUD1 (/ISO) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
1 | Q9WUD1 (/ISO) |
|
Ubiquitin-dependent SMAD protein catabolic process GO:0030579
The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.
|
1 | Q9WUD1 (/ISO) |
|
Endoplasmic reticulum unfolded protein response GO:0030968
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.
|
1 | Q9WUD1 (/IDA) |
|
Positive regulation of protein ubiquitination GO:0031398
Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
1 | Q9WUD1 (/ISO) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | Q9WUD1 (/ISO) |
|
Regulation of glucocorticoid metabolic process GO:0031943
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
|
1 | Q9WUD1 (/ISO) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
1 | Q9WUD1 (/IDA) |
|
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | Q9WUD1 (/ISO) |
|
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | D4A4T0 (/IDA) |
|
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | Q9WUD1 (/ISO) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | Q9WUD1 (/ISO) |
|
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
|
1 | Q9WUD1 (/IDA) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
1 | Q9WUD1 (/ISO) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
1 | Q9WUD1 (/ISS) |
|
Chaperone-mediated autophagy GO:0061684
The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.
|
1 | D4A4T0 (/IMP) |
|
Chaperone-mediated autophagy GO:0061684
The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.
|
1 | Q9WUD1 (/ISO) |
|
Protein K63-linked ubiquitination GO:0070534
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
1 | Q9WUD1 (/ISO) |
|
Protein K63-linked ubiquitination GO:0070534
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
|
1 | Q9WUD1 (/ISS) |
|
Cellular response to misfolded protein GO:0071218
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
|
1 | Q9WUD1 (/IMP) |
|
Cellular response to misfolded protein GO:0071218
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
|
1 | Q9WUD1 (/ISO) |
|
Cellular response to misfolded protein GO:0071218
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
|
1 | Q5ZHY5 (/ISS) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
1 | D4A4T0 (/IDA) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
1 | Q9WUD1 (/ISO) |
|
Positive regulation of chaperone-mediated protein complex assembly GO:0090035
Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
|
1 | Q9WUD1 (/ISO) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
14 |
D4A4T0 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(4 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
14 |
Q7ZTZ6 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(4 more) |
|
Ubiquitin conjugating enzyme complex GO:0031371
Any complex that possesses ubiquitin conjugating enzyme activity.
|
13 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(3 more) |
|
Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
12 |
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
Q9UNE7 (/ISS)
(2 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
12 |
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
Q9UNE7 (/TAS)
(2 more) |
|
Nuclear inclusion body GO:0042405
An intranuclear focus at which aggregated proteins have been sequestered.
|
12 |
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
Q9UNE7 (/IDA)
(2 more) |
|
Chaperone complex GO:0101031
A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
|
12 |
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
Q9UNE7 (/IPI)
(2 more) |
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Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
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1 | Q9WUD1 (/ISO) |
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Ubiquitin ligase complex GO:0000151
A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
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1 | Q9WUD1 (/ISS) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | D4A4T0 (/IDA) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | Q9WUD1 (/ISO) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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1 | Q9WUD1 (/ISO) |
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Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
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1 | Q9WUD1 (/ISO) |
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Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
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1 | Q9WUD1 (/ISO) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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1 | Q9WUD1 (/ISO) |
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Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
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1 | Q9WUD1 (/IDA) |
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Nuclear inclusion body GO:0042405
An intranuclear focus at which aggregated proteins have been sequestered.
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1 | Q9WUD1 (/ISO) |
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Chaperone complex GO:0101031
A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
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1 | Q9WUD1 (/ISO) |
