The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 72: dnaJ homolog subfamily C member 13 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O75165 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
5 D4AFX7 (/ISO) G3X922 (/ISO) Q3UQJ7 (/ISO) Q3UX52 (/ISO) Q8CHD7 (/ISO)
Regulation of early endosome to recycling endosome transport GO:1902954
Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport.
5 D4AFX7 (/ISO) G3X922 (/ISO) Q3UQJ7 (/ISO) Q3UX52 (/ISO) Q8CHD7 (/ISO)
Regulation of early endosome to late endosome transport GO:2000641
Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.
5 D4AFX7 (/ISO) G3X922 (/ISO) Q3UQJ7 (/ISO) Q3UX52 (/ISO) Q8CHD7 (/ISO)
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
1 O75165 (/HDA)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
1 O75165 (/IMP)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
1 O75165 (/TAS)
Regulation of early endosome to recycling endosome transport GO:1902954
Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport.
1 O75165 (/IMP)
Regulation of early endosome to late endosome transport GO:2000641
Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.
1 O75165 (/IMP)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 D4AFX7 (/ISO) G3X922 (/ISO) Q3UQJ7 (/ISO) Q3UX52 (/ISO) Q8CHD7 (/ISO)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
5 D4AFX7 (/ISO) G3X922 (/ISO) Q3UQJ7 (/ISO) Q3UX52 (/ISO) Q8CHD7 (/ISO)
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
5 D4AFX7 (/ISO) G3X922 (/ISO) Q3UQJ7 (/ISO) Q3UX52 (/ISO) Q8CHD7 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
5 D4AFX7 (/ISO) G3X922 (/ISO) Q3UQJ7 (/ISO) Q3UX52 (/ISO) Q8CHD7 (/ISO)
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
2 B3KN02 (/HDA) O75165 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O75165 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O75165 (/TAS)
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
1 O75165 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 O75165 (/HDA)
Secretory granule membrane GO:0030667
The lipid bilayer surrounding a secretory granule.
1 O75165 (/TAS)
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
1 O75165 (/IDA)
Azurophil granule membrane GO:0035577
The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
1 O75165 (/TAS)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 O75165 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 O75165 (/HDA)
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