The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 62: Serine/threonine-protein phosphatase 2A regulatory...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q38845 (/IPI) Q38845 (/IPI) Q38950 (/IPI) Q38950 (/IPI) Q38951 (/IPI)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
7 P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP)
Mitotic spindle assembly checkpoint GO:0007094
A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
7 P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP) P31383 (/IMP)
Regulation of phosphorylation GO:0042325
Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
3 Q38950 (/ISS) Q38950 (/ISS) Q38951 (/ISS)
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
2 Q38845 (/IMP) Q38845 (/IMP)
Abscisic acid-activated signaling pathway GO:0009738
A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
2 Q38845 (/TAS) Q38845 (/TAS)
Positive regulation of abscisic acid-activated signaling pathway GO:0009789
Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.
2 Q38845 (/IMP) Q38845 (/IMP)
Auxin polar transport GO:0009926
The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.
2 Q38845 (/IDA) Q38845 (/IDA)
Regulation of stomatal movement GO:0010119
Any process that modulates the frequency, rate or extent of stomatal movement.
2 Q38845 (/IMP) Q38845 (/IMP)
Regulation of protein dephosphorylation GO:0035304
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.
2 Q38845 (/IMP) Q38845 (/IMP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q38950 (/IEP) Q38950 (/IEP)
Cellular bud neck septin ring organization GO:0032186
Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.
1 Q5ADN1 (/IDA)
Cellular bud neck septin ring organization GO:0032186
Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.
1 Q5ADN1 (/IMP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) Q38845 (/IDA) Q38845 (/IDA) Q38951 (/IDA)
Protein phosphatase type 2A complex GO:0000159
A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
8 P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) Q5ADN1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
7 P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA)
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
7 P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
7 P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
7 P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA) P31383 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 Q38845 (/IDA) Q38845 (/IDA) Q38950 (/IDA) Q38950 (/IDA) Q38951 (/IDA)
Protein phosphatase type 2A complex GO:0000159
A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
3 Q38845 (/TAS) Q38845 (/TAS) Q38951 (/TAS)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
3 Q38845 (/IDA) Q38845 (/IDA) Q38951 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q38950 (/IDA) Q38950 (/IDA) Q38951 (/IDA)
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