The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 59: exportin-7 isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 Q9EPK7 (/IPI) Q9UIA9 (/IPI) Q9UIA9 (/IPI) Q9UIA9 (/IPI) Q9UIA9 (/IPI) Q9UIA9 (/IPI) Q9UIA9 (/IPI) Q9UIA9 (/IPI) Q9UIA9 (/IPI)
Nuclear export signal receptor activity GO:0005049
Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.
8 Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
2 Q9H2T7 (/NAS) Q9H2T7 (/NAS)
Ran GTPase binding GO:0008536
Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
2 Q99NF8 (/TAS) Q9EPK7 (/TAS)
Nuclear export signal receptor activity GO:0005049
Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.
1 Q9EPK7 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
8 Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
2 Q9H2T7 (/NAS) Q9H2T7 (/NAS)
Nucleocytoplasmic transport GO:0006913
The directed movement of molecules between the nucleus and the cytoplasm.
2 Q99NF8 (/TAS) Q9EPK7 (/TAS)
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
1 Q9EPK7 (/ISO)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
8 Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA) Q9UIA9 (/IDA)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2 Q9H2T7 (/NAS) Q9H2T7 (/NAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9EPK7 (/ISO)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
1 Q9EPK7 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9EPK7 (/ISO)
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